NIH-funded research NIH-funded research

HABS-HD Project 1: Understanding Alzheimer’s Biomarkers in Diverse Communities

Official title: HABS-HD - Project 1

Funded at University of North Texas Hlth Sci Ctr · NIH-11412505 · Data updated 2026-11-12

A large study is looking at Alzheimer’s biomarkers in adults 21 and older across diverse communities to help improve future treatments.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of North Texas Hlth Sci Ctr
NIH-funded
Lab location1 site (Fort Worth, United States)
Project startSeptember 30, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$404,259
NIH project number5U19AG078109-05
Project IDNIH-11412505 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 years and older, especially from African American and Hispanic communities, who may participate in biomarker studies or contribute data.

Less likely to help

Individuals without access to the study sites or who do not meet the biomarker or demographic criteria may not benefit.

What this research studies

This project focuses on how early Alzheimer’s biomarkers appear and behave in African American and Hispanic adults, not just non-Hispanic whites. Researchers will study biomarker patterns across adulthood to see how they relate to the AT(N) framework used in trials. The goal is to make biomarker-based therapies more relevant and effective for communities that have been underrepresented in dementia research. The work will involve community-based data collection and analysis to map biomarker trajectories over time.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and inclusive biomarker-based approaches for diagnosing and treating Alzheimer’s in diverse populations.

How similar studies have gone: Previous biomarker studies have shown promise in NHW populations but underrepresented groups need more validation; this study aims to extend those findings.

Where this research is happening

  • University of North Texas Hlth Sci Ctr
    Fort Worth, United States
    Active

Researchers

  • Principal investigator: O'bryant, Sid E — University of North Texas Hlth Sci Ctr
  • Study coordinator: O'bryant, Sid E

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.