Sponsor or institution
Clinical trials and research at University of North Carolina Charlotte
As of November 12, 2026, Find a Trial lists 2 clinical trials run by University of North Carolina Charlotte that are recruiting, in United States. There are also 59 NIH-funded research projects at this institution, with $22.0 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 2Clinical trials
- 59NIH research projects
- 1Country
All recruiting trials (2)
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Exploring the effects of Daoist standing meditation on well-being
This study is testing whether practicing Daoist standing meditation can improve well-being and reduce stress compared to doing a simple wall squat.
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Developing a model for measuring physical activity in young people
This study is trying to create a better way to measure how active young people are so that parents and doctors can help them live healthier lives.
NIH-funded research (newest 40 of 59)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Understanding how fetal male germ cells fix DNA breaks
Researchers are studying how DNA damage in fetal male germ cells is repaired to keep future sperm healthy.
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Automated single-cell heart cell measurements to test drugs
A new automated system will quickly measure electrical signals and beating force in heart cells derived from a patient’s own stem cells to help predict drug safety.
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Innate Immune Trigger to Boost Bone Infection Defense
Researchers are testing a way to wake up the body's own innate immune system to fight stubborn bone infections caused by Staphylococcus aureus, aiming to help people with osteomyelitis fight bacteria more effectively.
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Targeting Perp in pancreatic cancer and its muscle wasting
This NIH grant explores a gene called Perp as a potential target to slow pancreatic cancer growth and reduce cachexia in patients.
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Substance P and worsening bone infection from staph bacteria
Aims to understand if a nerve-related molecule called substance P makes bone infection from Staphylococcus aureus worse.
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Deciphering Pemphigus Risk Through Immune Gene Maps
A study to map the genetic and immune signals that raise the risk of pemphigus, a rare autoimmune skin disease, in adults.
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Mucin-1 targeted nanoparticles delivering chemotherapy for pancreatic cancer
A new targeted nanoparticle system is being developed to deliver chemotherapy directly to pancreatic cancer cells in order to improve treatment outcomes.
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Non-invasive fetal HLA and KIR genotyping from mom’s blood
A non-invasive test using the mother’s blood to identify fetal HLA and KIR genes early in pregnancy to help predict risk of preeclampsia, especially in African American pregnancies.
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Blocking Perp to slow pancreatic cancer and cancer-related muscle wasting
This project will test whether lowering a protein called Perp can shrink pancreatic tumors and help people with pancreatic cancer who are losing weight and muscle.
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Gut signals that protect cells and slow aging
This project looks at whether signals released by the gut can strengthen cells and help prevent age-related problems like dementia.
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Understanding how Hsp70 phosphorylation controls proteostasis
This NIH grant explores how a specific modification of the Hsp70 protein helps cells manage protein folding and stress, with a focus on yeast as a model.
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Smartphone-linked bedside test for heat- and pesticide-related health risks in farmworkers
A handheld smartphone-connected test to quickly detect pesticide exposure and early signs of kidney trouble for farmworkers.
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Clear cadence-based activity targets for children and teens
This project builds an easy-to-use, age-aware way to turn step rates and wearable data into meaningful activity levels for kids and young adults ages 6–20.
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How the APE1 protein controls a DNA damage checkpoint in cancer
This work looks at whether the APE1 protein turns on a DNA-damage checkpoint in cancer cells that affects tumor cell survival.
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Understanding How Hsp70 Helpers Keep Proteins Healthy in Cancer
This grant looks at how a key protein helper called Hsp70 works and changes in cancer cells to keep proteins correctly folded.
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Using AI across clinics to read eye scans for diabetic eye disease
This project trains AI on eye scans held at different hospitals to help doctors detect, predict, and track diabetic retinopathy in people with diabetes.
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MUC1-targeted nanoparticles that deliver two chemotherapy drugs to pancreatic cancer
A targeted nanoparticle is designed to carry gemcitabine and cisplatin into MUC1-positive pancreatic tumors to try to improve treatment for people with pancreatic ductal adenocarcinoma.
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Nerve peptide that may worsen Staph bone infections
This work is finding out whether a nerve chemical called substance P makes Staphylococcus aureus bone infections more inflammatory and damaging for people with osteomyelitis.
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Exploring how Hsp70 phosphorylation affects protein folding and cell stress responses
This study looks at how a special protein called Hsp70 helps cells stay healthy and function well when they're under stress, like heat, by checking how certain changes to Hsp70 affect its job in keeping other proteins in shape; it's mainly done in yeast but could help us understand how our own cells handle stress bette
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Software tools to visualize genomic data
This study is all about making it easier for biologists to understand and work with large sets of genetic information by creating user-friendly software that helps them see patterns and insights in the data.
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Understanding how APE1 protein helps in DNA damage response in cancer cells
This study is looking at how a protein called APE1 helps cancer cells fix their damaged DNA, which could lead to new ways to treat cancer.
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Mapping variations in natural killer cell receptors in diverse human populations
This study is looking at the differences in certain immune cells that help fight infections and cancer by examining DNA from over 2,100 people of different backgrounds, including African Americans and Native Americans, to better understand how these differences might affect health and disease.
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Understanding how individual factors affect treatment in dogs with leishmaniasis.
This study is looking at how well different treatments work for dogs with a disease called canine visceral leishmaniasis, and it wants to find out how things like the dog's health and other infections might affect their recovery, so we can help more dogs get better.
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Investigating how gut stress signals can promote healthy aging and protein balance
This study is looking at how our gut can send helpful signals to the rest of our body as we get older, especially to keep us healthy and prevent issues like dementia and metabolic problems, and it aims to find new ways to support healthy aging.
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Investigating how physical activity affects health in young people.
This study is looking at how physical activity affects the health of kids and young adults aged 6 to 20, and it wants to create an easy way to measure how much exercise they get each day, so we can help them be more active and healthy.
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Creating mobile health technology to help farmworkers facing heat and pesticide risks
This study is working on a mobile health tool to help migrant and seasonal farmworkers quickly check for health issues like kidney problems and pesticide poisoning, making it easier for them to get the care they need in tough working conditions.
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Exploring new fluorescent sensors to understand cell membrane dynamics
This study is working on creating special dyes that can help scientists see how electric signals change in cells, which could lead to a better understanding of how our bodies work, especially in thick tissues.
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Using light-activated silver nanoparticles to fight antibiotic-resistant bacteria
This study is exploring a new way to fight stubborn infections caused by antibiotic-resistant bacteria using special light-activated particles, which could help patients who struggle with these tough infections when regular antibiotics don't work.
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New technology to communicate with and modulate the human immune system
This study is exploring a new type of treatment called SMART NANPs that works with your immune system to help fight specific diseases, aiming to make therapies more effective and with fewer side effects, so you can have more personalized care.
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Investigating how bone cells respond to Staphylococcus aureus infections
This study is looking at how certain bone cells react to infections from a common bacteria that can cause bone problems, and it aims to find out how a specific part of the immune system helps manage inflammation and bone changes during these infections, which could lead to better understanding and treatment for people
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Understanding how bystanders can help with problematic alcohol use among college students
This study is looking at how college students can help each other when they see someone drinking too much, and it aims to create tools that help us understand why some people step in to help while others don’t, so we can find better ways to encourage everyone to take action.
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Understanding how work affects diabetes management in workers
This study is looking at how different work environments affect blue-collar and service workers with diabetes, aiming to find out what makes it harder for them to take care of their health while on the job, so we can create better support for them.
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Targeted nanoparticles for treating pancreatic cancer
This study is working on tiny particles that can deliver chemotherapy directly to pancreatic cancer cells, making the treatment more effective and helping patients get better results.
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Developing algorithms to analyze gene expression data in Alzheimer's disease
This study is looking at how to better understand gene activity in brain tissue from people with Alzheimer's disease, using smart computer techniques to pinpoint important genes that could help us find new treatments just for you.
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Using advanced AI to predict vision loss in patients with age-related macular degeneration
This study is working on using smart computer models to help predict when geographic atrophy, a serious eye condition related to aging, might start or get worse, so that patients at higher risk can get the care they need more often while keeping their personal information safe.
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Using light-activated silver nanoparticles to fight antibiotic-resistant bacteria
This study is exploring a new way to fight tough infections caused by antibiotic-resistant bacteria using special light-activated particles, which could lead to better treatment options for patients who struggle with these hard-to-treat germs.
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Mapping variations in natural killer cell receptors in diverse human populations
This study is looking at the differences in immune system cells called natural killer (NK) cells, which help fight infections and cancer, by examining DNA from over 2,150 people from different backgrounds, including African Americans and Native Americans, to better understand how these differences can affect health.
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Protecting nerves from damage caused by chemotherapy
This study is looking at how a drug called Fluocinolone acetonide might help prevent painful nerve damage from chemotherapy, especially for those receiving a common treatment called Paclitaxel, so patients can feel better while getting their cancer care.
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Exploring luminescent proteins and their interactions with gold compounds
This study is exploring how special glowing proteins work with tiny gold particles to develop new materials that could help with medical imaging and treatments, aiming to find patterns in the proteins that make them glow.
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How substance P affects bone damage from staph infections
This study is looking at how a substance called substance P might make inflammation and bone damage worse in people with staph infections, especially in cases of osteomyelitis, to help us understand how it affects bone health.
Quick answers
How many clinical trials run by University of North Carolina Charlotte are recruiting right now?
2, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.