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Clinical trials and research at Sunnybrook Health Sciences Centre

• 93Clinical trials
• 1New in 30 days
• 20Countries

Newest trials

All recruiting trials (93)

• How TikTok Trigger Warnings affect at-risk youth

  This study tests whether TikTok trigger warnings change how young people at risk of suicide feel and behave when they see suicide-related content.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07913854

• Can hepatic artery infusion chemotherapy enable liver surgery for colorectal cancer that has spread to the liver?

  This study tests whether hepatic artery infusion chemotherapy plus standard chemotherapy can make some inoperable colorectal liver metastases operable in patients.

  Recruiting Phase 2 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07764497

• Erector Spinae Plane vs Serratus Anterior Plane Catheter Infusions for Acute Pain in Traumatic Rib Fractures

  This trial tests whether ESP catheter infusions or SAP catheter infusions provide better pain control for adults with traumatic rib fractures.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07756047

• Safety and feasibility of a next-generation dome helmet for neuromodulation in OCD

  This study tests whether a new focused ultrasound helmet can safely help people with treatment-refractory OCD see if their symptoms improve.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07704632

• Focusing ultrasound to the central thalamus to help people with disorders of consciousness

  This study tests whether two sessions of low-intensity focused ultrasound can safely help people with severe brain injuries see if they become more awake or responsive.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07694258

• Next-Generation Dome Helmet for Focused Ultrasound Neuromodulation in Treatment-Resistant Substance Use Disorder

  This study tests whether focused ultrasound delivered through a Dome Helmet can be safely used to target brain regions and help adults with hard-to-treat substance use disorders see if their use declines.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07684976

• Radiation boost for painful spinal metastases

  This study will try adding an extra focused radiation boost to standard spine SBRT for adults with painful spinal metastases to see if it improves long-term tumor control and reduces pain.

  Recruiting Phase 2 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07478289

• Low-dose levetiracetam for people at increased risk of Alzheimer's disease

  This study will try short courses of low-dose levetiracetam to see if it reduces abnormal hippocampal brain activity in people who have memory complaints and a first-degree family history of Alzheimer's disease.

  Recruiting at 2 sites Phase 2 Sunnybrook Health Sciences Centre · Toronto, Ontario and 1 other locations · NCT07477431

• Daily temozolomide for older adults with newly diagnosed glioblastoma and unmethylated MGMT promoter

  This trial will test whether a modified daily temozolomide schedule helps people aged 65 and older with newly diagnosed glioblastoma whose tumors have an unmethylated MGMT promoter.

  Recruiting Phase 2 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07476794

• Spinal fluid and blood liquid biopsy for people with metastatic solid tumors with or without brain involvement

  This will test whether a one-time spinal fluid (CSF) and blood sample can find tumor DNA in people with metastatic solid tumors, including those with brain metastases or leptomeningeal disease.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07476781

• MR‑Linac guided adaptive 'dose‑painting' radiation with reduced margins for Grade 4 glioma

  This trial will test whether daily MRI‑guided adaptive 'dose‑painting' radiation with smaller treatment margins helps people with glioblastoma (Grade 4 astrocytoma) get better local tumor control and fewer side effects than standard radiation.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07459101

• Test of adding a very low-dose edoxaban to standard antiplatelet therapy to prevent another stroke in adults 75 and older

  This trial tests whether adding a tiny amount of edoxaban to aspirin or clopidogrel can better prevent a second stroke in people aged 75+ who recently had an ischemic stroke.

  Recruiting Phase 3 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07454707

• Goal-Directed Heart, Kidney, and Metabolic Care to Help Adults with Diabetic Kidney Disease

  This trial tests a structured, early CKM care plan alongside usual care to see if it is feasible and safe for adults with type 2 diabetes and diabetic kidney disease who are at high cardiovascular risk.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07434791

• Ketogenic Diet with Accelerated Brain Stimulation for Treatment‑Resistant Depression

  This study tests whether adding a ketogenic diet to a personalized accelerated brain stimulation treatment helps reduce depression symptoms in adults with treatment‑resistant depression.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07376018

• VR vs. mannequin ECT training: is VR as good for learning ECT skills?

  This trial tests whether virtual reality ECT training can match traditional mannequin-based training for medical students learning how to perform electroconvulsive therapy.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07350278

• Intercostal Neuralgia After Chest Tube Insertion in Traumatic Rib Fractures

  This observational study tests how often intercostal neuralgia develops after chest tube placement for rib fractures and what factors predict it.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07308587

• Virtual reality to reduce anxiety before MR-guided focused ultrasound for essential tremor

  This study tests whether watching a short virtual reality video can lower pre-treatment anxiety in adults having MRgFUS for medication-refractory essential tremor.

  Recruiting Sunnybrook Health Sciences Centre · North York, Ontario · NCT07287605

• Brain stimulation plus methylphenidate for apathy in Alzheimer's

  This trial will test whether combining short sessions of noninvasive brain stimulation (intermittent theta burst) with methylphenidate can reduce apathy in people with Alzheimer's disease or mixed Alzheimer's/vascular dementia.

  Recruiting Phase 2 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07279740

• Comparing a one-time intramuscular steroid shot versus a short oral steroid course for RA flares

  This tests whether a single intramuscular steroid injection or a short course of oral steroid pills gives better symptom relief for people with rheumatoid arthritis who are experiencing a flare.

  Recruiting at 5 sites Phase 4 Sunnybrook Health Sciences Centre · Toronto, Ontario and 4 other locations · NCT07245732

• Long-term outcomes after MRI-guided focused ultrasound thalamotomy for medication-resistant essential tremor

  This project will see if MRI-guided focused ultrasound thalamotomy provides lasting tremor relief and good long-term safety for people whose essential tremor has not responded to medications.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07212244

• Early Eptinezumab for Acute Post-Traumatic Headache

  This study tests whether a single infusion of eptinezumab can help people with acute post-traumatic headaches, particularly those with a migraine-like pattern, after a mild brain injury.

  Recruiting Phase 3 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07191145

• Focused ultrasound to open the blood-brain barrier in adults with high-grade glioma on chemotherapy

  This trial tests whether focused ultrasound using the Next Generation Dome Helmet can safely open the blood-brain barrier in adults with glioblastoma who are receiving maintenance temozolomide chemotherapy.

  Recruiting Phase 1 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07179328

• Combining Gamma Knife and Linac radiosurgery for large brain tumors and metastases

  This will test whether using both Gamma Knife and Linac stereotactic radiosurgery in adults with large brain tumors or brain metastases can improve tumor control and reduce side effects.

  Recruiting Phase 2 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07162246

• Twice-daily rTMS for Depressed Youth in Hospital

  This project will test whether giving twice-daily repetitive transcranial magnetic stimulation (rTMS) to hospitalized adolescents with moderate-to-severe depression is feasible while they attend on-unit schooling and receive therapeutic support.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07140575

• MRI-guided focused ultrasound capsulotomy for severe, treatment-resistant anorexia nervosa with OCD or depression

  This trial will test whether MRI-guided focused ultrasound capsulotomy can be safely used to help adults with long-standing, treatment-resistant anorexia nervosa who also have obsessive-compulsive disorder or major depression.

  Recruiting Phase 1 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07113665

• MR-guided focused ultrasound bilateral capsulotomy for refractory bipolar depression

  This will try MR-guided focused ultrasound capsulotomy to see if it helps adults with treatment-resistant bipolar depression.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07108257

• Focused ultrasound neuromodulation for treatment-resistant depression

  This trial will test whether MRI-guided focused ultrasound using the Next Generation Dome Helmet can safely reduce depressive symptoms in adults whose depression has not improved with standard treatments.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07094789

• Can newly trained clinicians use bedside lung ultrasound to detect a collapsed lung after heart surgery?

  This study will test whether medical trainees can use a bedside lung ultrasound to find a collapsed lung in adults after heart surgery.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07018856

• Quality of life after surgery for neuroendocrine tumors

  This study looks at how surgery for neuroendocrine tumors affects the quality of life for patients to help improve their care after the operation.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06981455

• Comparing Betamethasone and Moisturizer for Skin Care in Breast Cancer Patients

  This study is testing whether a skin cream called betamethasone can help prevent skin problems from radiation therapy in large-breasted breast cancer patients compared to using just a moisturizer.

  Recruiting Phase 3 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06915857

• Cannabis oil for restless legs syndrome

  This trial will test whether cannabis oil helps adults with moderate-to-severe restless legs syndrome feel less leg discomfort and sleep better.

  Recruiting at 2 sites Sunnybrook Health Sciences Centre · Toronto, Ontario and 1 other locations · NCT06863740

• Deep Brain Stimulation for cognitive issues after brain injury

  This study is testing whether Deep Brain Stimulation can help improve memory and thinking skills in people who have cognitive issues after a traumatic brain injury that haven't gotten better with other treatments.

  Recruiting Phase 1 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06818864

• Ketamine and virtual reality to treat treatment-resistant depression

  This study tests whether IV ketamine combined with immersive virtual reality can help adults with treatment-resistant depression see faster or better improvements.

  Recruiting Phase 3 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06781697

• Exploring brain activity changes in depression treatment with rTMS

  This study is testing how a treatment called rTMS changes brain activity in people with major depression to see if it can help improve their mood and reduce the chance of relapse.

  Recruiting Phase 1 Sunnybrook Health Sciences Centre · North York, Ontario and 1 other locations · NCT06719427

• Comparing two ultrasound techniques for heart surgery

  This study is testing which ultrasound method, done on the chest or during surgery, gives better measurements of heart size in adults having heart surgery.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06715371

• Genotype-guided P2Y12 inhibitor selection versus standard clopidogrel for symptomatic intracranial atherosclerosis

  This test will see if using a point-of-care CYP2C19 genetic test to guide whether people who recently had a TIA or ischemic stroke from intracranial atherosclerosis should take ticagrelor plus aspirin instead of standard clopidogrel plus aspirin to lower the chance of another stroke.

  Recruiting Sunnybrook Health Sciences Centre · Calgary, Alberta and 1 other locations · NCT06714526

• Deep Brain Stimulation for Patients with Severe PTSD

  This study is testing if a surgery that uses deep brain stimulation can help people with severe PTSD who haven't found relief from other treatments.

  Recruiting Phase 1 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06705296

• MRI-guided ultrasound treatment for advanced breast cancer

  This study is testing if using MRI-guided ultrasound with tiny bubbles can make radiation therapy work better for people with advanced breast cancer who can't have surgery.

  Recruiting Phase 1 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06633601

• Hyperbaric Oxygen Therapy for Pain from Endometriosis

  This study is testing if Hyperbaric Oxygen Therapy can help women with endometriosis who have been in pain for a long time feel better while they wait for surgery.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06579040

• Evaluating treatment strategies for Gram-negative bloodstream infections

  This study is testing different treatment options for hospitalized patients with Gram-negative bloodstream infections to see which ones work best and improve their recovery.

  Recruiting at 41 sites Sunnybrook Health Sciences Centre · Kogarah, New South Wales and 40 other locations · NCT06537609

• Cognitive Behavioural Therapy for youth with mood and anxiety disorders

  This study is testing a new type of Cognitive Behavioural Therapy called CBT-MyOWL for young people aged 14-19 with mood and anxiety disorders to see if it helps them stick with treatment and feel better compared to standard therapy.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06532500

• Perioperative duloxetine to reduce opioid use after knee replacement

  This trial will test whether taking 60 mg duloxetine starting two weeks before and continuing after knee replacement helps people with knee osteoarthritis use fewer opioid pain medicines in the first week after surgery.

  Recruiting at 2 sites Phase 4 Sunnybrook Health Sciences Centre · Toronto, Ontario and 1 other locations · NCT06423716

• Examining the link between sleep and cognitive performance in older adults

  This study is testing how different aspects of sleep affect memory and thinking skills in older adults using a wearable device to track their sleep.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06423118

• Comparing breathing support methods for preterm infants

  This study is testing which breathing support method, CPAP or NIPPV, works better for very low birth weight preterm infants by comparing how their diaphragm functions while using each method.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06295484

• OURA ring wearable monitoring for adults with myelodysplastic syndromes

  This pilot will test whether adults with MDS can wear an OURA ring regularly and upload biometric data so clinicians can link those measurements with quality of life and transfusion status.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06270771

• Screening for brain metastases in patients with advanced breast cancer

  This study is testing how common hidden brain metastases are in patients with advanced breast cancer and looking at their experiences during the screening process.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06247449

• MRI-guided ultrasound treatment for breast cancer

  This study is testing a new treatment for breast cancer that uses MRI-guided ultrasound to boost the effects of radiation therapy and see how well it works for patients.

  Recruiting Phase 2 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06185972

• De-escalated radiation therapy for localized prostate cancer

  This study is testing a lower dose of targeted radiation therapy for men with localized prostate cancer to see if it can effectively treat the cancer while causing fewer side effects.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06177093

• Testing psilocybin's effects on brain activity in depression

  This study is testing if psilocybin can change brain activity linked to mood in people with major depression to see if it helps them feel better.

  Recruiting Phase 2 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06072898

• Hyperbaric oxygen plus PENTOCLO for jaw bone damage after radiation

  This trial will test if adding a year-long PENTOCLO medicine regimen to hyperbaric oxygen helps people with osteoradionecrosis of the mandible heal better than hyperbaric oxygen alone.

  Recruiting Phase 3 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06055257

• Using MRI to guide brain stimulation for memory improvement

  This study is testing a new way to boost memory by using MRI scans to guide brain stimulation for people with mild cognitive impairment and healthy individuals.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06050603

• Tucatinib combined with radiation for HER2-positive breast cancer with leptomeningeal disease

  This study is testing if combining radiation with a new treatment for HER2-positive breast cancer can help patients with brain involvement live longer and feel better.

  Recruiting at 2 sites Phase 2 Sunnybrook Health Sciences Centre · Ottawa, Ontario and 1 other locations · NCT06016387

• Cannabidiol for managing agitation in Alzheimer's disease

  This study is testing whether pure CBD capsules can help reduce agitation in people with Alzheimer's disease.

  Recruiting at 5 sites Phase 2 Sunnybrook Health Sciences Centre · Calgary, Alberta and 4 other locations · NCT06014424

• Using MRI to evaluate low-grade brain tumors

  This study is testing a special type of MRI to see if it can help doctors better understand and predict how low-grade brain tumors in younger patients might change over time.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario and 1 other locations · NCT05996653

• Accelerated repetitive transcranial magnetic stimulation for ALS

  This study is testing a new type of brain stimulation to see if it can help people with ALS feel better and improve their muscle strength over 24 weeks.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05983211

• Testing a new dosing method of niraparib for ovarian cancer treatment

  This study is testing a new way to give niraparib to see if it helps people with newly diagnosed advanced ovarian cancer stay healthy longer after their initial chemotherapy.

  Recruiting Phase 2 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05961124

• Using immersive 360-degree video to help medical students navigate hospitals

  This study tests if using immersive 360-degree virtual reality videos can help medical students feel less anxious and find their way around hospitals better than regular videos.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05894005

• Using inhaled sedatives to improve outcomes in critically ill children

  This study is testing if using inhaled sedatives can help critically ill children on ventilators feel less confused and improve their recovery compared to regular IV sedation.

  Recruiting at 3 sites Phase 3 Sunnybrook Health Sciences Centre · Hamilton, Ontario and 2 other locations · NCT05867472

• Freezing Nerves to Relieve Pain from Rib Fractures

  This study is testing if freezing the nerves can help people with rib fractures feel less pain compared to a fake treatment.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05865327

• Using brain imaging and TMS to treat severe depression

  This study is testing a new way to treat severe depression using brain scans and a special type of magnetic stimulation to see if it helps people who haven't found relief from other treatments.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05813093

• Using mixed reality for medical training and assessment

  This study is testing a new mixed reality training program using holographic patients to see if it helps medical professionals make better decisions in emergency situations compared to traditional training methods.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05729802

• MRI-guided ultrasound treatment for skin cancer

  This study is testing a new treatment that uses ultrasound and microbubbles to see if it can make radiation therapy work better for people with skin cancer.

  Recruiting Phase 1 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05620290

• Comparing two versus five MRI-guided treatments for prostate cancer

  This study is testing if giving radiation treatment for prostate cancer in just two sessions instead of five can work just as well for men with localized prostate cancer.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05600400

• Using a hydrogel spacer to reduce side effects of salvage radiation for prostate cancer

  This study is testing whether a special gel placed between the prostate and rectum can help reduce side effects from radiation treatment in men with recurring prostate cancer.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05597852

• Using brain stimulation to treat apathy in Alzheimer's disease

  This study is testing whether a brain stimulation treatment can help reduce feelings of apathy in people with Alzheimer's disease, including those who are taking a medication for it.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05561205

• Comparing heart surgery options for patients with severe coronary artery disease

  This study is testing which heart surgery option, either bypass surgery or a less invasive procedure, works better for people with severe coronary artery disease and weakened heart function.

  Recruiting at 40 sites Sunnybrook Health Sciences Centre · Los Angeles, California and 45 other locations · NCT05427370

• Comparing two methods for fixing broken collarbones

  This study is testing whether using two small plates instead of one for fixing broken collarbones helps patients heal better and reduces the chances of needing more surgery later.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05231343

• Reducing hearing loss from cisplatin chemotherapy using sodium thiosulfate and mannitol

  This study is testing if adding sodium thiosulfate and mannitol to cisplatin chemotherapy can help adults avoid hearing loss caused by the treatment.

  Recruiting Phase 2 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05129748

• A program to reduce postoperative delirium in older surgical patients

  This study is testing a program to see if special education and care can help prevent confusion after surgery in older patients aged 60 and above.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05114876

• Exercise and brain stimulation for improving memory in patients with vascular cognitive impairment

  This study is testing whether combining exercise with brain stimulation can help improve memory in people with vascular cognitive impairment who have finished cardiac rehab.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05079464

• Quality of life and outcomes after SBRT for primary kidney cancer

  This trial will test whether stereotactic body radiotherapy (SBRT) helps people with primary kidney cancer who cannot or will not have surgery and how it affects their quality of life.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT05023265

• Comparing two radiation therapies for prostate cancer treatment

  This study is testing whether a newer type of radiation therapy called SBRT is better than traditional radiation treatments for men with prostate cancer.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT04861415

• Using targeted radiation therapy for prostate cancer that resists standard treatment

  This study is testing a new type of targeted radiation therapy for men with prostate cancer that isn't responding to standard treatment, to see if it can help control their cancer while they continue their current medication.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT04838899

• Combining two advanced radiation therapies for prostate cancer treatment

  This study is testing if combining two types of radiation therapy can help men with low-risk prostate cancer get better results with fewer treatments and less side effects.

  Recruiting Phase 2/3 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT04654338

• Using patient avatars to guide treatment for metastatic breast cancer

  This study is testing whether using patient avatars made from biopsy samples can help find the best treatments for people with metastatic breast cancer.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT04608357

• Using nabilone to treat agitation in Alzheimer's patients

  This study is testing if nabilone can help reduce agitation in people with Alzheimer's disease to improve their overall well-being.

  Recruiting at 5 sites Phase 3 Sunnybrook Health Sciences Centre · Calgary, Alberta and 7 other locations · NCT04516057

• Observational study on mood and cognition in people with Type 2 Diabetes and prediabetes

  This study looks at how mood and thinking skills are affected in people with Type 2 diabetes or prediabetes to see what factors might play a role over 18 months.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT04455867

• Using photoacoustic imaging to assess breast cancer and treatment response

  This study is testing a new imaging technique to see if it can help tell the difference between harmless and cancerous breast lumps and track how tumors change during chemotherapy.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT04428528

• Evaluating Photoacoustic Imaging for Head and Neck Cancer

  This study is testing a new imaging technique to see how head and neck cancer patients' lymph nodes change during their treatment with radiation, with or without chemotherapy.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT04428515

• Improving cognitive outcomes in patients with sleep apnea using home testing

  This study is trying to see if home testing for sleep apnea can help diagnose the condition better in people with cognitive issues like Alzheimer's, making it easier for them to get the treatment they need.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT04335994

• Effects of Dexmedetomidine on cognitive recovery after cardiac surgery

  This study is testing if a medication called Dexmedetomidine can help people recover their thinking skills better after having heart surgery.

  Recruiting at 3 sites Phase 4 Sunnybrook Health Sciences Centre · Vancouver, British Columbia and 7 other locations · NCT04289142

• Evaluating a new ECG system for MRI scans

  This study tests a new ECG system designed for MRI scans to see if it can better monitor heart problems in patients with atrial fibrillation.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT04247685

• Using ultrasound and spectroscopy to monitor breast cancer treatment response

  This study is testing if ultrasound and spectroscopy can help doctors see how well breast cancer treatments are working for patients sooner, so they can make changes if needed.

  Recruiting Sunnybrook Health Sciences Centre · Houston, Texas and 2 other locations · NCT04134780

• Investigating the impact of clonal hematopoiesis on chemotherapy complications in lymphoma patients

  This study is trying to see if having a certain blood condition called CHIP makes older lymphoma patients more likely to have problems like low blood counts and infections while they are getting chemotherapy.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT04053439

• Using ultrasound imaging and spectroscopy to analyze breast masses

  This study is testing if special ultrasound techniques can help doctors better understand and identify breast lumps in patients suspected of having breast cancer.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT04050423

• Using ultrasound to improve chemotherapy for breast cancer

  This study is testing whether using ultrasound to monitor chemotherapy can help women with breast cancer get better treatment adjustments and outcomes compared to standard methods.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT04050228

• Using ultrasound spectroscopy to predict radiation treatment response in cancer patients

  This study is testing if special ultrasound techniques can help predict how well radiation treatment works for patients with prostate, rectal, and head and neck cancers.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT03908684

• Comparing two surgical techniques for massive rotator cuff tears

  This study is testing whether a new surgical technique called superior capsular reconstruction works better than a partial rotator cuff repair for people with large, irreparable rotator cuff tears who haven't found relief from other treatments.

  Recruiting at 2 sites Sunnybrook Health Sciences Centre · Toronto, Ontario and 1 other locations · NCT03617562

• Preventing blood clots in patients with severe traumatic brain injury

  This study is testing whether using a combination of special leg devices and blood thinners can better prevent blood clots in people with severe brain injuries without causing more bleeding in the brain.

  Recruiting at 12 sites Phase 3 Sunnybrook Health Sciences Centre · Calgary, Alberta and 11 other locations · NCT03559114

• Using advanced MRI to study brain metastases in cancer patients

  This study is testing a special MRI technique to see how brain tumors in cancer patients use energy and how that might affect their treatment outcomes.

  Recruiting Phase 1 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT03324360

• Screening for anal cancer in women with vulvar lesions

  This study is testing if screening for anal cancer with Pap smears can help women over 40 who have vulvar lesions catch any problems early and improve their health.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT03061435

• Imaging the heart's metabolism using a special carbon-13 compound

  This study is testing a new imaging method using a special carbon-13 compound to see how well the hearts of people with high blood pressure and thickened heart muscle are working.

  Recruiting Phase 1 Sunnybrook Health Sciences Centre · Toronto, Ontario and 1 other locations · NCT02648009

• Using ultrasound imaging to predict breast cancer treatment response

  This study tests if different types of ultrasound imaging can help predict how well breast cancer patients respond to their chemotherapy and radiotherapy treatments.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT00437879

Quick answers

How many clinical trials run by Sunnybrook Health Sciences Centre are recruiting right now?

93, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 20 countries. The most sites are in Canada (93 trials), United States (2 trials), Austria (1 trial), Brazil (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 12, Phase 1: 9, Phase 3: 8, Phase 4: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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