Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Erector Spinae Plane vs Serratus Anterior Plane Catheter Infusions for Acute Pain in Traumatic Rib Fractures

Official title: Erector Spinae Plane vs Serratus Anterior Plane Catheter Infusions for Acute Pain Management in Patients With Traumatic Rib Fractures: a Single Centre, Randomized Controlled Trial

Run by Sunnybrook Health Sciences Centre · NCT07756047 · Data updated 2026-11-12

This trial tests whether ESP catheter infusions or SAP catheter infusions provide better pain control for adults with traumatic rib fractures.

More Rib Fracture Multiple trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment66 (estimated)
SponsorSunnybrook Health Sciences Centre
Academic / other
Locations1 site (Toronto, Ontario)
StatusRecruiting
StartedSeptember 9, 2026
Main results expectedDecember 31, 2027
Study endsJune 30, 2028
Registry record updatedOctober 23, 2026
Trial IDNCT07756047 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults over 18 with unilateral or bilateral traumatic rib fractures (at least 3 fractures per side) admitted within 72 hours and with significant chest pain at eligibility.

Probably not a fit

Patients with severe brain injury, planned surgery within 72 hours, coagulopathy, active infection at catheter sites, or contraindications to nerve blocks may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with rib fractures receive continuous catheter-based regional anesthesia to manage pain while reducing opioid use. The study compares erector spinae plane (ESP) catheters to serratus anterior plane (SAP) catheters for ongoing analgesia. Participants are adults with multiple rib fractures admitted to hospital, and pain relief, opioid-sparing effects, and safety are monitored. The approach aims to improve breathing and reduce pulmonary complications by better pain control. The trial does not have a defined phase or randomized designation in the provided details.

Why it matters

Potential benefit: If successful, patients may experience better pain control with less opioid use and fewer respiratory complications.

How similar studies have gone: Regional anesthesia for rib fractures has shown promise in reducing opioid needs, but direct comparison between ESP and SAP catheters is less well established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \>18;
* Traumatic rib fractures (unilateral or bilateral);
* Minimum of 3 rib fractures per side;
* Admitted to hospital for \<72 hours
* NRS pain score \> 4 at rest or with movement for chest pain at the time of eligibility assessment

Exclusion Criteria:

* Severe traumatic brain injury (Glasgow Coma Scale \< 9);
* Surgery performed/planned within 72 hours of catheter infusion start;
* Uncontrolled coagulopathy;
* Skin infection or anatomical abnormality (i.e. open fracture) at insertion sites;
* Allergy to local anesthetic;
* Chronic high dose opioid use preadmission (Morphine Equivalent Dose \> 30mg per day);
* Pregnancy;
* Acute respiratory failure requiring intubation at enrolment;
* Inability to comply with Intravenous Patient-Controlled Analgesia use;
* Contraindications to nerve blocks
* High likelihood of loss to follow-up

Where it's running

  • Sunnybrook Health Sciences Centre
    Toronto, Ontario, Canada
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.