Erector Spinae Plane vs Serratus Anterior Plane Catheter Infusions for Acute Pain in Traumatic Rib Fractures
Official title: Erector Spinae Plane vs Serratus Anterior Plane Catheter Infusions for Acute Pain Management in Patients With Traumatic Rib Fractures: a Single Centre, Randomized Controlled Trial
Run by Sunnybrook Health Sciences Centre · NCT07756047 · Data updated 2026-11-12
This trial tests whether ESP catheter infusions or SAP catheter infusions provide better pain control for adults with traumatic rib fractures.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 66 (estimated) |
| Sponsor | Sunnybrook Health Sciences Centre Academic / other |
| Locations | 1 site (Toronto, Ontario) |
| Status | Recruiting |
| Started | September 9, 2026 |
| Main results expected | December 31, 2027 |
| Study ends | June 30, 2028 |
| Registry record updated | October 23, 2026 |
| Trial ID | NCT07756047 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 with unilateral or bilateral traumatic rib fractures (at least 3 fractures per side) admitted within 72 hours and with significant chest pain at eligibility.
✕Probably not a fit
Patients with severe brain injury, planned surgery within 72 hours, coagulopathy, active infection at catheter sites, or contraindications to nerve blocks may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults with rib fractures receive continuous catheter-based regional anesthesia to manage pain while reducing opioid use. The study compares erector spinae plane (ESP) catheters to serratus anterior plane (SAP) catheters for ongoing analgesia. Participants are adults with multiple rib fractures admitted to hospital, and pain relief, opioid-sparing effects, and safety are monitored. The approach aims to improve breathing and reduce pulmonary complications by better pain control. The trial does not have a defined phase or randomized designation in the provided details.
Why it matters
Potential benefit: If successful, patients may experience better pain control with less opioid use and fewer respiratory complications.
How similar studies have gone: Regional anesthesia for rib fractures has shown promise in reducing opioid needs, but direct comparison between ESP and SAP catheters is less well established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>18; * Traumatic rib fractures (unilateral or bilateral); * Minimum of 3 rib fractures per side; * Admitted to hospital for \<72 hours * NRS pain score \> 4 at rest or with movement for chest pain at the time of eligibility assessment Exclusion Criteria: * Severe traumatic brain injury (Glasgow Coma Scale \< 9); * Surgery performed/planned within 72 hours of catheter infusion start; * Uncontrolled coagulopathy; * Skin infection or anatomical abnormality (i.e. open fracture) at insertion sites; * Allergy to local anesthetic; * Chronic high dose opioid use preadmission (Morphine Equivalent Dose \> 30mg per day); * Pregnancy; * Acute respiratory failure requiring intubation at enrolment; * Inability to comply with Intravenous Patient-Controlled Analgesia use; * Contraindications to nerve blocks * High likelihood of loss to follow-up
Where it's running
-
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada Recruiting
Study contacts
- Study coordinator: Howard Meng, MD
- Email: howard.meng@sunnybrook.ca
- Phone: 416-480-4864
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.