Cognitive Behavioural Therapy for youth with mood and anxiety disorders
Official title: I-CARE: A Pilot Study of Cognitive Behavioural Therapy(CBT) for Mood and Anxiety Disorders
Run by Sunnybrook Health Sciences Centre · NCT06532500 · Data updated 2026-11-12
This study is testing a new type of Cognitive Behavioural Therapy called CBT-MyOWL for young people aged 14-19 with mood and anxiety disorders to see if it helps them stick with treatment and feel better compared to standard therapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 14 Years to 19 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Sunnybrook Health Sciences Centre Academic / other |
| Locations | 1 site (Toronto, Ontario) |
| Status | Recruiting |
| Started | October 24, 2024 |
| Main results expected | September 1, 2027 |
| Study ends | September 1, 2027 |
| Registry record updated | May 13, 2025 |
| Trial ID | NCT06532500 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are youth aged 14-19 with a primary diagnosis of mood or anxiety disorders who can engage with the therapy.
✕Probably not a fit
Patients currently undergoing CBT or those with active psychosis or mania may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the feasibility and acceptability of a novel Cognitive Behavioural Therapy approach called CBT-MyOWL for youth aged 14-19 with mood and anxiety disorders. The study compares CBT-MyOWL to standard CBT to determine which method leads to better patient retention and outcomes. Key objectives include assessing the completion rates of the therapy and improvements in mental health indicators such as depression, anxiety, and self-harm. The trial aims to provide insights into the effectiveness of literature-based interventions in enhancing therapeutic engagement.
Why it matters
Potential benefit: If successful, this study could improve treatment retention and mental health outcomes for youth with mood and anxiety disorders.
How similar studies have gone: Other studies have shown positive outcomes with CBT approaches, but the specific CBT-MyOWL intervention is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 14-19 * Primary diagnosis of a mood disorder or an anxiety disorder * Ability to understand written and spoken English and to read a novel * Treating physician considers CBT as indicated for the patient Exclusion Criteria: * Patients already participating in active CBT therapy or recently completed CBT treatment (within the past 3 months) * Active psychosis or mania
Where it's running
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Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada Recruiting
Study contacts
- Principal investigator: Mark Sinyor, MD — Sunnybrook Health Sciences Centre
- Study coordinator: Prudence Chan, HBSc
- Email: poming.chan@sri.utoronto.ca
- Phone: 416-480-4070
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.