Cognitive Behavioural Therapy for youth with mood and anxiety disorders

I-CARE: A Pilot Study of Cognitive Behavioural Therapy(CBT) for Mood and Anxiety Disorders

Not applicable Interventional Sunnybrook Health Sciences Centre · NCT06532500

This study is testing a new type of Cognitive Behavioural Therapy called CBT-MyOWL for young people aged 14-19 with mood and anxiety disorders to see if it helps them stick with treatment and feel better compared to standard therapy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages14 Years to 19 Years
SexAll
SponsorSunnybrook Health Sciences Centre Academic / other
Locations1 site (Toronto, Ontario)
Trial IDNCT06532500 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the feasibility and acceptability of a novel Cognitive Behavioural Therapy approach called CBT-MyOWL for youth aged 14-19 with mood and anxiety disorders. The study compares CBT-MyOWL to standard CBT to determine which method leads to better patient retention and outcomes. Key objectives include assessing the completion rates of the therapy and improvements in mental health indicators such as depression, anxiety, and self-harm. The trial aims to provide insights into the effectiveness of literature-based interventions in enhancing therapeutic engagement.

Who should consider this trial

Good fit: Ideal candidates are youth aged 14-19 with a primary diagnosis of mood or anxiety disorders who can engage with the therapy.

Not a fit: Patients currently undergoing CBT or those with active psychosis or mania may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve treatment retention and mental health outcomes for youth with mood and anxiety disorders.

How similar studies have performed: Other studies have shown positive outcomes with CBT approaches, but the specific CBT-MyOWL intervention is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged 14-19
* Primary diagnosis of a mood disorder or an anxiety disorder
* Ability to understand written and spoken English and to read a novel
* Treating physician considers CBT as indicated for the patient

Exclusion Criteria:

* Patients already participating in active CBT therapy or recently completed CBT treatment (within the past 3 months)
* Active psychosis or mania

Where this trial is running

Toronto, Ontario

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Mood DisordersAnxiety Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.