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Clinical trials and research at Sixth Affiliated Hospital, Sun Yat-sen University
As of November 12, 2026, Find a Trial lists 65 clinical trials run by Sixth Affiliated Hospital, Sun Yat-sen University that are recruiting, in China. By phase: Phase 2 (17), Phase 3 (7), Phase 4 (3), Phase 2/3 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 65Clinical trials
- 1Country
Newest trials
All recruiting trials (65)
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Endoscopic stricturotomy vs balloon dilation for small bowel Crohn’s stricture
This trial tests whether endoscopic stricturotomy can be safely and effectively used to treat small bowel fibrotic strictures in Crohn’s disease, compared with endoscopic balloon dilation.
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Prediction of postoperative recurrence in Crohn's disease after surgery
A multicenter study will test a multimodal model to predict which Crohn's patients are likely to have disease recur after intestinal resection.
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Lymphatic-sparing short-course radiotherapy with chemo-immunotherapy before surgery for locally advanced ESCC
This study tests whether a short course of targeted radiotherapy combined with camrelizumab and nab-paclitaxel/carboplatin can shrink locally advanced esophageal squamous cell carcinoma enough for surgical removal.
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Tributyrin as a dietary supplement to help prevent radiation-induced rectal injury during rectal cancer chemoradiation
This study tests whether adding tributyrin to standard chemoradiotherapy helps prevent acute radiation-induced rectal injury in people with locally advanced rectal cancer.
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Biomarker Discovery and Validation Platform for Inflammatory Bowel Disease
Researchers are testing biomarker models to see if they can measure and predict inflammation and treatment response in people with Crohn's disease, ulcerative colitis, or related IBD.
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Nodal-Region Sparing Short-Course RT with PD-1 Antibody and Bevacizumab for Rectal Cancer
This study tests whether a nodal-region sparing short-course radiotherapy followed by chemotherapy plus a PD-1 antibody and bevacizumab is better than the standard short-course radiotherapy with chemotherapy for patients with pMMR/MSS locally advanced rectal cancer.
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Short-course radiotherapy followed by PD-1 inhibitor and FOLFOX vs standard chemoradiotherapy for high‑risk locally advanced lower rectal cancer
This trial tests whether giving a short course of radiotherapy followed by a PD-1 inhibitor and FOLFOX can be better than the usual long-course chemoradiotherapy for adults with high‑risk, locally advanced, pMMR/MSS lower rectal cancer.
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Superior hypogastric plexus block to improve recovery after laparoscopic colorectal cancer surgery
This will test whether adding a superior hypogastric plexus block helps adults having laparoscopic colorectal cancer surgery recover faster and have less pain.
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Short-course radiotherapy plus intensified chemotherapy and targeted therapy with immunotherapy for high-risk rectal cancer
This trial tests whether adding targeted therapy and a PD-1 inhibitor to a short course of radiotherapy and standard chemotherapy helps high-risk pMMR/MSS rectal cancer patients, compared with the same radiotherapy and chemotherapy alone.
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IL-23 inhibitors for adults with active Crohn's disease in routine care
This project will see if IL-23 blockers like guselkumab or risankizumab help adults with active Crohn's disease and are safe when used in everyday clinical practice.
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TNFi plus low-dose upadacitinib versus TNFi dose intensification for Crohn's disease with suboptimal response
This trial tests whether adding low-dose upadacitinib to a standard TNF blocker helps adults with moderate-to-severe Crohn's disease who haven't responded well to standard-dose infliximab or adalimumab, compared with increasing the TNFi dose.
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Exclusive enteral nutrition for adults with active, complicated Crohn's disease
This test checks whether exclusive enteral nutrition (a complete liquid diet) can induce remission and improve symptoms in adults with active or complicated Crohn's disease.
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Upadacitinib with or without vedolizumab for induction in moderate-to-severe ulcerative colitis
This study tests whether adding vedolizumab to upadacitinib helps adults with moderate-to-severe ulcerative colitis achieve better short-term (8-week) control than upadacitinib alone.
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Using MRI and blood markers to tell pseudoprogression from real tumor growth after rectal cancer immunotherapy.
This project will test whether combining serial multiparametric rectal MRIs with blood markers and clinical signs can tell pseudoprogression from true progression in people with stage II–IV rectal cancer starting immunotherapy.
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How types of radiation-caused rectal injury relate to recovery and outcomes
This project will try to see if different clinical types of radiation-caused rectal injury predict recovery and long-term outcomes in adults aged 18–80.
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Measuring how common and how treatment-resistant difficult-to-treat Crohn's disease is in China.
This project will measure how common difficult-to-treat Crohn's disease is in adults in China and see how their treatment responses and prognosis compare to other Crohn's patients.
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Titrated ciprofol anesthesia to prevent low blood pressure in older adults having laparoscopic abdominal surgery
This will test whether carefully titrated ciprofol-based anesthesia helps prevent low blood pressure during laparoscopic abdominal surgery in people aged 65 and older.
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Robot-assisted versus endoscopic breast-conserving surgery for breast cancer
This test compares robot-assisted and endoscopic breast-conserving surgery in women with a single breast tumor who want to keep their breast, to see which approach gives better surgical and cosmetic results.
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Stereotactic body radiation therapy for unresectable locally recurrent rectal cancer
This will try high-precision stereotactic body radiation therapy (SBRT) to control unresectable locally recurrent rectal cancer in adults who cannot have curative surgery.
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Node-sparing low-dose radiotherapy combined with chemotherapy and PD-1 blocker for high-risk pMMR/MSS locally advanced colon cancer.
This trial tests whether adding node-sparing low-dose radiotherapy to standard chemotherapy and a PD-1 blocker can improve tumor response in adults with high-risk, locally advanced pMMR/MSS colon cancer before surgery.
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Metformin before surgery and risk of nausea and vomiting after anesthesia.
This project will see if people who take metformin before general anesthesia have different rates or severity of postoperative nausea and vomiting compared with people not on metformin.
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Node-sparing hypofractionated radiotherapy with chemotherapy and PD-1 blockade for high-risk MSS/pMMR locally advanced colon cancer
This trial will test whether node-sparing, short-course radiotherapy combined with chemotherapy and a PD-1 blocker can improve pre-surgery tumor response in adults with high-risk, microsatellite-stable (pMMR/MSS) locally advanced colon cancer.
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IL-23 monoclonal antibody treatment for Crohn's disease and ulcerative colitis
This trial will test if an IL-23 monoclonal antibody helps adults aged 18–65 with moderate to severe Crohn's disease or ulcerative colitis.
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Neoadjuvant mFOLFOX with Citrus Flavonoid Tablets for YWHAB-High Locally Advanced Rectal Cancer
In people with locally advanced rectal cancer who have high YWHAB expression, this study tests whether adding citrus flavonoid tablets to a standard mFOLFOX neoadjuvant regimen helps shrink tumors before surgery.
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Gut and tumor bacteria patterns in metastatic versus non-metastatic colorectal cancer
This project will test whether bacteria in the gut and tumor differ between people whose colorectal cancer has spread and those whose cancer has not to see if bacterial signatures can help predict spread.
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Repeat liposomal bupivacaine for pain after anal fistula surgery.
We will see if giving a second dose of liposomal bupivacaine 72 hours after anal fistula surgery reduces postoperative pain in adults.
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Heart monitoring for cancer patients receiving chemotherapy and targeted drugs
This project will test whether regular heart checks (blood biomarkers, ECG, and echocardiogram) can predict serious heart problems in adults getting chemotherapy or targeted cancer drugs.
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Short-course radiotherapy plus chemotherapy with optional PD-1 antibody and bevacizumab before surgery for pMMR/MSS locally advanced rectal cancer
This trial tests whether adding a PD‑1 antibody and bevacizumab to short-course radiotherapy followed by chemotherapy before surgery helps people with pMMR/MSS locally advanced rectal cancer.
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Megestrol acetate to prevent weight loss during preoperative chemotherapy for locally advanced colorectal cancer
This trial tests whether taking megestrol acetate during mFOLFOX6 neoadjuvant chemotherapy can prevent weight loss and improve appetite in adults with locally advanced colorectal cancer.
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Pharmacist-led Medication Therapy Management to improve anticoagulant safety after colorectal cancer surgery
This will try a pharmacist-led Medication Therapy Management (MTM) program to reduce blood clots and bleeding in people who had colorectal cancer surgery and are taking anticoagulants.
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Node-sparing radiotherapy with chemotherapy and PD-1 inhibitor for rectal cancer
This study is testing a new treatment for mid-low rectal cancer that combines special radiation, chemotherapy, and an immune booster to see if it helps patients respond better while protecting their lymph nodes.
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Combining node-sparing radiotherapy with chemotherapy and immunotherapy for metastatic colorectal cancer
This study is testing a new treatment that combines a special type of radiation with chemotherapy and immunotherapy to see if it can help people with metastatic colorectal cancer live longer and feel better.
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Combining long-course radiotherapy, chemotherapy, and PD-1 inhibitor for high-risk rectal cancer
This study is testing a new treatment plan that combines radiation, chemotherapy, and a PD-1 inhibitor to see if it helps people with high-risk rectal cancer do better than with standard treatments.
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Combining Ustekinumab with Semi-Enteral Nutrition for Crohn's Disease Before Surgery
This study is testing if combining a medication called Ustekinumab with a special diet can help adults with Crohn's Disease feel better and get healthier before surgery.
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Treatment of active anal fistulas in Crohn's disease with Upadacitinib
This study is testing if Upadacitinib can help people with Crohn's disease who have active anal fistulas feel better and heal faster.
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Combining radiation therapy and PD-1 antibody for liver metastases from colorectal cancer
This study is testing if combining a special type of radiation therapy with a new immune treatment can help people with liver cancer from colorectal cancer feel better and live longer.
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Combination therapy for advanced colorectal cancer
This study is testing a new combination treatment for people with advanced colorectal cancer to see if it can help them respond better to therapy and live longer compared to a standard treatment.
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Evaluating Upadacitinib for Inflammatory Bowel Disease
This study is testing how well the oral medication Upadacitinib works for people in China with Inflammatory Bowel Disease who haven't responded to other treatments.
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Using fecal microbiota transplantation to treat radiation-induced proctopathy
This study is testing if fecal microbiota transplantation can help people with severe rectal bleeding caused by radiation treatment feel better.
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Using dietary supplements to treat rectal injury from radiation
This study is testing whether a dietary supplement called tributyrin can help people with chronic rectal injury from radiation feel better and improve their quality of life.
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Combining radiation therapy and PD-1 antibody for advanced rectal cancer
This study is testing if combining a special type of radiation therapy with a new immune treatment can help people with advanced rectal cancer live longer and possibly become eligible for surgery.
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Using imaging to predict cancer response in rectal cancer patients
This study is testing a special type of MRI to see if it can help predict how well rectal cancer patients respond to treatment before they have surgery.
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Exploring the anatomy of the breast fascia system
This study looks at the structure of breast tissue in patients who have had certain types of breast surgery to see how it develops and how it might relate to breast health.
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Comparing dual-target therapy with intensified Ustekinumab for Crohn's disease
This study is testing if a new combination treatment of Ustekinumab and Upadacitinib can help people with Crohn's disease feel better compared to a higher dose of Ustekinumab alone.
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Perioperative oxaliplatin plus S-1 with H. pylori eradication for locally advanced gastric and gastroesophageal junction adenocarcinoma
This trial tests whether adding a 14-day H. pylori eradication regimen to perioperative oxaliplatin plus S-1 chemotherapy helps people with H. pylori–positive resectable locally advanced gastric or gastroesophageal junction cancer.
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Predicting how well gastric cancer patients respond to chemotherapy using AI
This study tests if using AI to combine imaging and tissue data can help predict how well advanced gastric cancer patients will respond to chemotherapy.
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Using Midazolam to Improve Postoperative Pain Relief for Colorectal Cancer Patients with Anxiety or Sleep Issues
This study is testing if giving midazolam before surgery can help colorectal cancer patients with anxiety or sleep issues feel less pain and recover faster afterward.
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Combining PD-1 antibody with chemoradiotherapy for rectal squamous cell carcinoma
This study is testing if adding a PD-1 antibody to standard chemotherapy and radiation can help people with non-metastatic rectal squamous cell carcinoma live longer and have better treatment results.
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Predicting treatment response in advanced rectal cancer using multi-omics data
This study is testing a new way to predict how well treatment will work for people with advanced rectal cancer by using different types of data from their scans and blood tests.
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Comparing surgical methods to reduce recurrence in Crohn's disease after surgery
This study is testing whether a specific surgical method can help people with Crohn's disease avoid having their symptoms come back after surgery.
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Understanding delirium risk after major abdominal surgery in older adults
This study looks at what might increase the risk of confusion after major abdominal surgery in older adults to help improve their care and recovery.
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Combining Vedolizumab and Upadacitinib for Ulcerative Colitis Treatment
This study is testing if combining two medications, Vedolizumab and Upadacitinib, can help people with moderate to severe ulcerative colitis feel better faster and stay well longer.
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Neoadjuvant therapy for synchronous multiple primary colorectal cancer
This study is testing a new combination of immunotherapy and chemotherapy to see if it helps people with multiple primary colorectal cancer feel better and have better outcomes.
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Comparing two surgical techniques for anal function after low rectal cancer surgery
This study is testing which of two surgical methods helps people with ultra-low rectal cancer have better bowel control and quality of life after surgery.
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Comparing chemotherapy and observation for liver metastasis in colorectal cancer
This study is testing if some patients with liver metastasis from colorectal cancer can safely skip chemotherapy after surgery and just be monitored instead.
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Combining targeted therapy with chemotherapy for advanced colorectal cancer
This study is testing if adding a targeted therapy to standard chemotherapy can help people with advanced colorectal cancer live longer without their cancer coming back after surgery.
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Maintenance therapy for colorectal cancer patients after liver surgery
This study is testing if adding maintenance therapy to standard chemotherapy can help colorectal cancer patients with liver metastases live longer without their cancer getting worse after surgery.
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Using AI and MRI to predict treatment response in advanced rectal cancer
This study is testing if a new AI tool using MRI scans can help doctors predict how well treatment will work for people with advanced rectal cancer.
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Combination of chemotherapy and immunotherapy for advanced esophagogastric junction cancer
This study is testing if combining a new immune therapy with chemotherapy can help people with advanced esophagogastric junction cancer have smaller tumors that are easier to remove and improve their chances of living longer.
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Combination therapy for gastric cancer with inoperable bowel obstruction
This study is testing a combination of three cancer drugs to see if it can help people with gastric cancer and a blocked bowel feel better and improve their condition.
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Watchful waiting for patients with specific rectal cancer after immunotherapy
This study tests if carefully monitoring patients with certain types of rectal cancer who responded well to immunotherapy can be a safe alternative to immediate surgery.
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Comparing Tubeless NOSES and Traditional Surgery for Rectosigmoid Cancers
This study is testing if a new type of surgery called Tubeless NOSES is as safe and effective as traditional surgery for people with rectosigmoid cancers.
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Evaluating the need for adjuvant chemotherapy in advanced colorectal cancer after preoperative treatment
This study is testing if patients with advanced colorectal cancer who have already had treatment before surgery really need more chemotherapy afterward to stay cancer-free.
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Comparing two surgical approaches for low rectal cancer treatment
This study is testing whether a combination of two surgical methods for low rectal cancer works better than just one after patients have received chemotherapy and radiation.
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Surgery for rectal cancer after chemotherapy and radiation
This study is testing a new type of surgery for rectal cancer patients who have had chemotherapy and radiation to see if it helps them have better bowel function and fewer complications after the operation.
Quick answers
How many clinical trials run by Sixth Affiliated Hospital, Sun Yat-sen University are recruiting right now?
65, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in China. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 17, Phase 3: 7, Phase 4: 3, Phase 2/3: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.