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Clinical trials and research at Sheba Medical Center

• 29Clinical trials
• 1Country

Newest trials

All recruiting trials (29)

• Tele-diabetes remote monitoring for kids with type 1 diabetes

  This study tests a tele-diabetes remote system that uses WhatsApp alerts to help children and teens manage their type 1 diabetes at home.

  Recruiting Sheba Medical Center · Ramat Gan · NCT07828106

• Ex Vivo Drug Response Testing in Lung Adenocarcinoma with Malignant Pleural Effusions

  This study tests whether the way cancer cells from pleural effusions respond to drugs outside the body can predict how patients will respond to treatment.

  Recruiting Sheba Medical Center · Ramat Gan, Israel · NCT07636252

• SHARP: Personalized Health and Behavior Plan to Lower Biological Age in Older Adults

  A 12-month randomized trial tests whether a personalized health and behavior program can lower biological age and improve function in healthy adults over 50.

  Recruiting Sheba Medical Center · Ramat Gan, Tel Aviv · NCT07596576

• Using a portable VR headset to measure pupil reactions for diagnosing and monitoring head injury

  This research tests whether a VR headset that flashes brief, gentle colored lights can detect and track traumatic brain injury by measuring how the pupil responds in people with TBI, similar non-TBI trauma patients, and healthy adults.

  Recruiting Sheba Medical Center · Tel HaShomer, Tel Aviv (Gosh Dan) · NCT07474987

• Group versus individual MDMA-assisted therapy for PTSD related to the October 7, 2023 events

  The study will see if group-based MDMA-assisted therapy works as well and is as safe as individual MDMA-assisted therapy for adults diagnosed with PTSD after October 7, 2023.

  Recruiting at 2 sites Phase 2 Sheba Medical Center · Beersheba and 1 other locations · NCT07469098

• How arm position changes blood pressure readings during pregnancy

  We will see if different arm positions (supported at heart level, on the lap, or unsupported at the side) change blood pressure readings in pregnant women attending a high-risk clinic.

  Recruiting Sheba Medical Center · Ramat Gan · NCT07405723

• Carbetocin to prevent heavy bleeding after twin birth

  This trial tests whether a single dose of carbetocin given after the second twin is born reduces heavy bleeding compared with standard oxytocin in people delivering twins.

  Recruiting Phase 4 Sheba Medical Center · Ramat Gan · NCT07401524

• Using brief electric fields during spine surgery to let CNS tumor markers into the blood

  Try whether a short, targeted application of electric pulses during intradural spinal tumor surgery makes brain-derived proteins detectable in a blood sample for adults having this operation.

  Recruiting Sheba Medical Center · Ramat Gan · NCT07224451

• Adding azithromycin to ampicillin for late PPROM

  This test sees if adding a single dose of azithromycin to the usual ampicillin/amoxicillin treatment helps newborns when membranes break early between 34.0 and 36.6 weeks.

  Recruiting Phase 4 Sheba Medical Center · Ramat Gan, Israel · NCT07183462

• How OPMD progresses in people in Israel

  This project will track adults with OPMD or suggestive symptoms in Israel over time to see how swallowing, eyelid droop, muscle strength, breathing, thinking, and oral health change.

  Recruiting Sheba Medical Center · Ramat Gan · NCT07146256

• Anti-CD22 CAR‑T cell therapy for CD22‑positive B‑cell cancers

  This trial will try a one-time CAR‑T cell therapy that targets CD22 in children and adults whose relapsed or refractory B‑cell cancers still express CD22 after prior treatments, including CD19‑directed therapy.

  Recruiting Phase 1/2 Sheba Medical Center · Ramat Gan, G · NCT07135466

• Stage II-III NSCLC patients who start neoadjuvant chemo-immunotherapy but do not undergo planned surgery

  This project will see what happens to people with stage II-III non-small cell lung cancer who begin neoadjuvant chemo-immunotherapy but end up not having the planned surgery.

  Recruiting Sheba Medical Center · Ramat Gan · NCT07131163

• Oral health and saliva thickness in oculopharyngeal muscular dystrophy (OPMD)

  This study will see if adults with OPMD have different oral health, thicker saliva, or unique saliva biochemical signs compared with their household members without OPMD.

  Recruiting Sheba Medical Center · Ramat Gan · NCT07118280

• High-antibody plasma treatment for hospitalized West Nile fever patients.

  This trial will test whether giving plasma rich in West Nile antibodies helps adults hospitalized with severe West Nile fever recover faster and avoid serious complications.

  Recruiting Phase 2 Sheba Medical Center · Ramat Gan · NCT07094724

• Comparing Paromomycin and Metronidazole for Treating Dientamoeba Fragilis in Adults

  This study tests whether the medication paromomycin works better than metronidazole for treating adults with gastrointestinal issues caused by Dientamoeba fragilis.

  Recruiting Sheba Medical Center · Ramat Gan, Israel · NCT06907498

• Using Allocetra to treat osteoarthritis in the jaw joint

  This study is testing a new treatment called Allocetra to see if it can help people with jaw joint osteoarthritis who haven't found relief from other treatments.

  Recruiting Phase 1 Sheba Medical Center · Ramat Gan · NCT06748651

• Lifestyle program plus weekly semaglutide for older adults with type 2 diabetes and obesity

  In adults aged 65 and older with type 2 diabetes and obesity, this study tests whether adding an online exercise program and personalized nutrition to weekly semaglutide helps slow muscle and physical function decline more than semaglutide with general health advice.

  Recruiting Sheba Medical Center · Jerusalem, Israel and 1 other locations · NCT06497595

• Evaluating resistance mechanisms to neoadjuvant osimertinib in lung cancer

  This study is testing if a drug called osimertinib can help people with certain types of lung cancer before their surgery and to see how the cancer might resist the treatment.

  Recruiting at 2 sites Phase 2 Sheba Medical Center · Ramat Gan, Israel and 1 other locations · NCT06206850

• Investigating the impact of sexual intercourse on embryo transfer outcomes

  This study is testing if having sex the night after a frozen embryo transfer helps improve the chances of pregnancy for women undergoing this procedure.

  Recruiting Sheba Medical Center · Ramat Gan · NCT06134609

• Using CPAP to protect lungs and heart during radiation for esophageal cancer

  This study tests if using a CPAP machine during radiation treatment can help protect the lungs and heart of people with esophageal cancer.

  Recruiting Sheba Medical Center · Ramat Gan · NCT06037902

• Using crizanlizumab alone or with nivolumab for treating advanced glioblastoma and melanoma with brain metastases

  This study is testing if a new treatment called crizanlizumab, alone or with another drug called nivolumab, can help people with advanced brain cancer from glioblastoma or melanoma that has spread to the brain.

  Recruiting Phase 2 Sheba Medical Center · Ramat Gan, Israel · NCT05909618

• Using the Medtronic 780G system for managing type 1 diabetes in children

  This study is trying to see how well the Medtronic 780G insulin delivery system works for managing type 1 diabetes in children and teens aged 7-18 over six months.

  Recruiting Sheba Medical Center · Ramat Gan, Please Select · NCT05908708

• CAR-T therapy targeting BCMA for multiple myeloma patients

  This study is testing a new CAR-T therapy for people with tough-to-treat multiple myeloma to see if it is safe and effective.

  Recruiting Phase 1/2 Sheba Medical Center · Ramat Gan · NCT05243212

• Combination of Pembrolizumab and Lenvatinib for Ovarian Cancer

  This study is testing a combination of two medications, pembrolizumab and lenvatinib, to see if they can help women with recurrent ovarian cancer that is sensitive to platinum-based treatments.

  Recruiting Phase 2 Sheba Medical Center · Ramat Gan · NCT04519151

• Registry for bariatric surgery quality control

  This study is setting up a registry to track the results and safety of bariatric surgery for people who are severely obese to help improve surgical practices.

  Recruiting Sheba Medical Center · Ramat Gan · NCT04040413

• Assessing eye function in patients with pseudotumor cerebri using a new pupillometry technique

  This study tests a new eye test to see if it can help find vision problems in people with pseudotumor cerebri compared to healthy individuals.

  Recruiting Sheba Medical Center · Tel HaShomer · NCT03304314

• Understanding how physical parameters affect ophthalmic lasers

  This study is trying to see how different physical factors affect the use of lasers in eye treatments to make them safer and more effective for patients.

  Recruiting Sheba Medical Center · Tel HaShomer · NCT02023073

• Improving quality of life after heart valve replacement

  This study looks at how people feel and do after getting a heart valve replacement to see if there are patterns that could help improve future treatments.

  Recruiting at 5 sites Sheba Medical Center · Jerusalem and 4 other locations · NCT02023060

• Evaluating pupil response to light in patients with retinal conditions

  This study is testing a new way to check vision by measuring how pupils respond to light in people with retinal conditions like glaucoma to see if it’s better than current methods.

  Recruiting Sheba Medical Center · Tel HaShomer · NCT02014389

Quick answers

How many clinical trials run by Sheba Medical Center are recruiting right now?

29, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in Israel. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 5, Phase 1/2: 2, Phase 4: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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