Using the Medtronic 780G system for managing type 1 diabetes in children
Official title: Title: Closed-loop Medtronic 780G System in Youth With Type 1 Diabetes: AWeSoMe Study Group Prospective Trial
Run by Sheba Medical Center · NCT05908708 · Data updated 2026-11-12
This study is trying to see how well the Medtronic 780G insulin delivery system works for managing type 1 diabetes in children and teens aged 7-18 over six months.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 1 Year to 21 Years |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | Sheba Medical Center Government |
| Locations | 1 site (Ramat Gan, Please Select) |
| Status | Recruiting |
| Started | June 1, 2023 |
| Main results expected | July 1, 2026 |
| Study ends | July 1, 2026 |
| Registry record updated | April 9, 2026 |
| Trial ID | NCT05908708 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children and youth aged 7-18 years diagnosed with type 1 diabetes who are starting the Medtronic 780G system.
✕Probably not a fit
Patients under the age of 1 year or those not using the 780G system will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to gather data on Israeli children and youth aged 7-18 years who are using the Medtronic 780G closed-loop insulin delivery system. It will assess glycemic control, psychosocial aspects, and various health parameters over a six-month period. Participants will be monitored at baseline, one month, three months, and six months after starting the system. The study involves multiple pediatric diabetes clinics in Israel and focuses on patients who have chosen to use the 780G system as part of their diabetes management.
Why it matters
Potential benefit: If successful, this study could lead to improved glycemic control and better psychosocial outcomes for children with type 1 diabetes.
How similar studies have gone: Other studies have shown positive outcomes with similar closed-loop insulin delivery systems, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Diagnosis of type 1 diabetes Diabetes duration ≥ 6 months Routine attendance at clinic visits Initiation of 780G system usage Exclusion Criteria: Children under the age of 1 year Children without 780G system
Where it's running
-
Sheba Medical Center
Ramat Gan, Please Select, Israel Recruiting
Study contacts
- Study coordinator: Noah Gruber, MD
- Email: noah.gruber@sheba.health.gov.il
- Phone: +972507181666
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Semaglutide on body composition in adults with type 1 diabetes and overweight/obesity
This study tests whether weekly semaglutide changes body composition in adults with type 1 diabetes who are overweight or obese, compared with a placebo over 24 weeks.
-
Next Generation Extended Wear Sensors in Type 1 and Type 2 Diabetes
This study tests a new extended wear sensor and algorithm in people with type 1 or type 2 diabetes to see how well it works across adults and children.
-
CGM-guided carb awareness education for adults with Type 1 diabetes
This study tests whether teaching mealtime insulin dosing using CGM data helps adults with Type 1 diabetes who don’t usually count carbs.
-
Two Different Therapeutic Distractions Used During Blood Draw for Children Aged 5–7
This study tests whether two distraction methods during blood sampling can reduce pain, fear, and anxiety in 5–7 year-olds compared with routine care.
-
Safety and effectiveness of GLP-1 receptor agonists and SGLT inhibitors added to insulin in adults with type 1 diabetes
This registry will see if adding GLP-1RA or SGLTi therapies to insulin helps adults with type 1 diabetes over one year.
-
Think-Find-Solve activities for insulin self-management in children with type 1 diabetes
A behavior-change activity book is tested with children aged 8–12 with type 1 diabetes and their parents to see if it improves daily insulin self-management.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.