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Clinical trials and research at Shanghai Chest Hospital

• 48Clinical trials
• 3Countries

Newest trials

All recruiting trials (48)

• Sacituzumab Govitecan plus Tislelizumab for advanced esophageal cancer

  This phase II study tests whether the cancer-fighting drug sacituzumab tirumotecan (SKB264) combined with tislelizumab can help adults with advanced esophageal squamous cell carcinoma that progressed after initial immunotherapy.

  Recruiting at 2 sites Phase 2 Shanghai Chest Hospital · Shanghai and 1 other locations · NCT07811752

• Femtosecond laser imaging with FastLung AI for intraoperative lung diagnosis

  This study tests whether labeling-free femtosecond laser imaging with FastLung AI can match the accuracy of standard frozen sections for diagnosing lung tumors during surgery.

  Recruiting at 4 sites Shanghai Chest Hospital · Shanghai, Shanghai Municipality and 4 other locations · NCT07681245

• Pre-Emptive Parecoxib for Pain During CT-Guided Lung Nodule Localization

  This study tests whether giving parecoxib sodium before a CT-guided needle localization of lung nodules can reduce pain for patients undergoing VATS.

  Recruiting Phase 4 Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT07675473

• Induction chemoimmunotherapy plus chemoradiotherapy and consolidation immunotherapy in unresectable locally advanced NSCLC

  This trial tests induction chemoimmunotherapy followed by chemoradiotherapy and consolidation immunotherapy in adults with unresectable stage III NSCLC to see if it can improve outcomes compared with the standard PACIFIC approach.

  Recruiting Phase 1/2 Shanghai Chest Hospital · Shanghai, Xuhui · NCT07632365

• Prospective cohort of SCLC patients receiving radiotherapy-based comprehensive treatment

  This project will collect detailed clinical, imaging, pathology, and molecular data from adults with limited-stage SCLC who receive radiotherapy with or without chemotherapy and immunotherapy to try to identify which radiotherapy timing, dose, and combinations work best.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT07565532

• Septum-guided segmentectomy for deep early-stage lung cancer

  This trial tests a precise septum-guided, lung-sparing surgery to remove small, deep early-stage non-small cell lung cancers in adults while preserving more healthy lung tissue.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT07564557

• Vebreltinib with Platinum Chemotherapy as First-line Treatment for MET-Overexpressing NSCLC

  This study tests whether adding vebreltinib to platinum-based chemotherapy can help adults with advanced NSCLC that overexpress MET and lack driver mutations respond to treatment as a first option.

  Recruiting Phase 2 Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT07549061

• Robotic-assisted sleeve lobectomy after neoadjuvant chemoimmunotherapy for stage IIB-III non-small cell lung cancer

  See how often robotic-assisted sleeve lobectomy after neoadjuvant chemoimmunotherapy succeeds and what makes the surgery harder for adults with stage IIB-III non-small cell lung cancer.

  Recruiting at 10 sites Shanghai Chest Hospital · Fuzhou, Fujian and 9 other locations · NCT07541521

• Tumor downstaging and robotic lung surgery after pre‑operative chemo‑immunotherapy for stage IIB–III NSCLC

  This project will see if tumor and lymph node shrinkage after pre‑surgery chemo‑immunotherapy leads to safer operations and quicker recoveries for people with stage IIB–III non‑small cell lung cancer who have robotic lung surgery.

  Recruiting at 10 sites Shanghai Chest Hospital · Fuzhou, Fujian and 9 other locations · NCT07528066

• Electroacupuncture plus dolasetron to prevent nausea and vomiting after thoracoscopic lung surgery

  This trial will test whether adding electroacupuncture to standard anti-nausea medicines (dolasetron and dexamethasone) reduces postoperative nausea and vomiting in high-risk adults undergoing video-assisted thoracoscopic lung surgery.

  Recruiting Shanghai Chest Hospital · Shanghai · NCT07515027

• Blood test using cfDNA fragment patterns to tell if a lung nodule is cancer

  This project will see if a blood test that analyzes cfDNA fragments can tell adults with CT-detected lung nodules whether the nodules are benign or malignant.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT07399210

• Surufatinib plus chemotherapy versus surufatinib alone for pulmonary neuroendocrine tumors

  This trial will test whether adding chemotherapy to surufatinib helps people with pulmonary neuroendocrine tumors get better tumor responses or live longer and whether the combination is safe.

  Recruiting Phase 2 Shanghai Chest Hospital · Hefei, Anhui and 3 other locations · NCT07357623

• Sleeve lobectomy after neoadjuvant therapy for non-small cell lung cancer

  This will see if minimally invasive sleeve lobectomy (VATS or RATS) works as well or better than open thoracotomy for adults with non-small cell lung cancer who received pre-surgery (neoadjuvant) treatment.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT07135856

• Optimized posterior wall ablation for persistent atrial fibrillation

  This study tests whether adding posterior wall ablation and electrogram-guided ablation to standard pulmonary vein isolation helps people with persistent atrial fibrillation who are having their first ablation.

  Recruiting Shanghai Chest Hospital · Shanghai · NCT07122336

• QL1706 with chemotherapy induction followed by immunotherapy consolidation in limited-stage SCLC after chemoradiotherapy

  This study tests if QL1706 given with chemotherapy induction can improve outcomes for adults with limited-stage small cell lung cancer after chemoradiation, with follow-up immunotherapy consolidation and biomarker analysis.

  Recruiting Phase 2 Shanghai Chest Hospital · Shanghai · NCT07091305

• Contrast-enhanced endobronchial ultrasound for lung lesions and chest lymph nodes

  This test checks whether adding a microbubble contrast agent to endobronchial ultrasound helps diagnose lung lesions and enlarged intrathoracic lymph nodes in adults who need EBUS-TBNA.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT07060378

• Osimertinib-based adaptive treatment guided by ctDNA EGFR mutation monitoring for advanced EGFR-mutant NSCLC

  This Phase 2 trial tests whether using blood ctDNA to guide when to continue or step down osimertinib (with or without chemotherapy) can keep cancer controlled while reducing treatment side effects for people with advanced EGFR-mutant non-small cell lung cancer who clear EGFR mutations from plasma after initial therapy

  Recruiting Phase 2 Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT07058519

• Bronchoscopic microwave ablation for lung tumors

  This study will test whether delivering microwave energy through a bronchoscope can safely treat small primary or metastatic lung tumors in adults who cannot or will not have surgery or radiation.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06969014

• Robotic-assisted bronchoscopy versus ultrathin bronchoscopy with virtual navigation for diagnosing peripheral lung nodules

  This trial will test whether robotic-assisted bronchoscopy works as well as ultrathin bronchoscopy with virtual bronchoscopic navigation to diagnose peripheral lung nodules in adults who need a non-surgical biopsy.

  Recruiting at 5 sites Shanghai Chest Hospital · Jinan, Shandong and 4 other locations · NCT06962436

• Comparing two methods for diagnosing lymph node issues

  This study is testing a new method for taking tissue samples from lymph nodes to see if it works better and is safer than the standard method for people who need a diagnosis.

  Recruiting Shanghai Chest Hospital · Shenyang, Liaoning and 2 other locations · NCT06913569

• Cryoablation versus thoracoscopic surgery for ground-glass lung nodules

  This trial will test whether cryoablation or minimally invasive thoracoscopic surgery works better and is safer for adults with 8–20 mm ground-glass lung nodules suspected to be early-stage cancer.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06848881

• DNA and RNA testing for treatment-resistant lung cancer

  This study is trying to see how many patients with advanced lung cancer are resistant to standard treatments because of hidden gene issues and how those with known gene problems respond to targeted therapies compared to those without.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06846762

• Investigating biomarkers for myocarditis in lung cancer patients treated with immune checkpoint inhibitors

  This study is trying to find specific blood markers that can help doctors understand and predict heart problems in lung cancer patients who are being treated with immune therapies.

  Recruiting Shanghai Chest Hospital · Shanghai · NCT06818149

• Exploring sugar chains in lung cancer immunotherapy response

  This study is testing if changes in sugar chains in the blood can help predict how well people with non-small cell lung cancer respond to immunotherapy treatments.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06730503

• Combining sintilimab with chemotherapy and radiotherapy for advanced esophageal cancer

  This study is testing if combining an immunotherapy drug called sintilimab with chemotherapy and radiation can help people with advanced esophageal cancer feel better and improve their treatment outcomes.

  Recruiting Phase 2 Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06709417

• Combination therapy for extensive-stage small cell lung cancer

  This study is testing a new combination of medications to see if it can help people with extensive-stage small cell lung cancer feel better and improve their treatment outcomes.

  Recruiting Phase 2 Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06698965

• Intrathecal treatment for lung cancer with leptomeningeal metastases

  This study is testing a new way to deliver two cancer drugs directly into the spine to see if it helps people with lung cancer that has spread to the brain and who haven't responded well to other treatments.

  Recruiting Phase 1 Shanghai Chest Hospital · Shanghai · NCT06663306

• Using tislelizumab and chemotherapy for lung cancer surgery

  This study is testing if combining a new drug called tislelizumab with chemotherapy can help people with a specific type of lung cancer respond better before surgery.

  Recruiting Phase 2 Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06659042

• Freezing small peripheral lung tumors through the chest versus through the airways

  This trial will test whether freezing small peripheral lung tumors through the chest or through the airways works better and is safer for adults with early-stage lung cancer who can't or won't have surgery.

  Recruiting Shanghai Chest Hospital · Guangzhou, Guangdong and 4 other locations · NCT06572540

• Comparing two methods of ablation for early-stage lung cancer

  This study is testing which of two different methods for treating early-stage lung cancer works better and is safer for patients.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06503744

• Improving patient outcomes after lung cancer surgery using a mobile platform

  This study is testing a mobile app to help lung cancer patients manage their recovery after surgery by tracking symptoms and improving communication with their doctors.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06483295

• Neoadjuvant therapy for resectable stage II-III lung cancer

  This study is testing if adding a type of radiation therapy to an immunotherapy drug and chemotherapy can help people with early-stage lung cancer have better surgery results.

  Recruiting Phase 3 Shanghai Chest Hospital · Shanghai · NCT06437977

• Neoadjuvant PD-1 blockade for elderly patients with esophageal cancer

  This study is testing a new treatment for older patients with esophageal cancer to see if it can help them have better surgery results and live longer.

  Recruiting Phase 2 Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06385730

• Predicting lymph node metastasis in non-small cell lung cancer using blood tests and imaging

  This study is testing if blood tests and imaging can help predict if non-small cell lung cancer has spread to lymph nodes in patients before surgery.

  Recruiting Shanghai Chest Hospital · Shanghai · NCT06358222

• Exploring the link between psychological distress and treatment outcomes in lung cancer patients

  This study looks at how stress and emotional struggles affect the success of cancer treatments in people with advanced lung cancer.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06218901

• Combining immunotherapy with chemoradiotherapy for advanced esophageal cancer

  This study is testing a new treatment that combines immunotherapy with chemotherapy and radiation to see if it helps people with advanced esophageal cancer live longer and complete their treatment better.

  Recruiting Phase 1/2 Shanghai Chest Hospital · Shanghai · NCT06173986

• Subsegmental versus segmental thermal vapor ablation for severe emphysema

  This trial tests whether treating smaller lung subsegments with bronchoscopic thermal vapor ablation works better and is as safe as treating whole segments for people with severe emphysema.

  Recruiting at 3 sites Shanghai Chest Hospital · Zhengzhou, Henan and 8 other locations · NCT06152107

• Combining Toripalimab with Cryoablation for Advanced Lung Cancer Treatment

  This study is testing if combining a new immune therapy called toripalimab with a freezing treatment can help people with advanced lung cancer who have had limited growth after their first treatment.

  Recruiting Phase 2 Shanghai Chest Hospital · Shanghai, Shanghai Municipality and 2 other locations · NCT06127303

• Combining Tislelizumab with Chemotherapy for Esophageal Cancer Treatment

  This study is testing if combining a new immune therapy called tislelizumab with chemotherapy can help people with esophageal cancer live longer and stay cancer-free after surgery.

  Recruiting Phase 2 Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06056336

• Combining radiotherapy with immunotherapy for advanced esophageal cancer

  This study is testing if adding low-dose and regular radiotherapy to standard immunotherapy and chemotherapy can help people with advanced esophageal cancer live longer without their disease getting worse.

  Recruiting at 2 sites Phase 2 Shanghai Chest Hospital · Shanghai and 1 other locations · NCT05978193

• Analysis and treatment options for small cell lung cancer

  This study looks at small cell lung cancer to see how its unique features can help doctors find better treatments and predict how well patients will respond to new therapies.

  Recruiting Shanghai Chest Hospital · Shanghai · NCT05945745

• Combining Toripalimab with Radiotherapy for Non-Small Cell Lung Cancer

  This study is testing if combining a new immune therapy with radiation can help people with early-stage non-small cell lung cancer do better after surgery compared to using chemotherapy.

  Recruiting Phase 2 Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT05798845

• Analysis of rare mutations in non-small cell lung cancer patients

  This study looks at rare genetic changes in people with non-small cell lung cancer to see if understanding these changes can lead to better treatment options.

  Recruiting at 2 sites Shanghai Chest Hospital · Shanghai, Shanghai Municipality and 1 other locations · NCT05701787

• Analysis and treatment options for thymic cancers

  This study is trying to find out how genetic changes in thymic cancers can help doctors create better, personalized treatments for patients.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT05667948

• Lung cancer screening using low-dose CT scans in high-risk individuals

  This study is testing if low-dose CT scans can help find lung cancer earlier in people aged 45 to 75 who are at high risk.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT05494021

• Combining Dacomitinib and Anlotinib for Advanced Lung Cancer Treatment

  This study is testing if combining two drugs, dacomitinib and anlotinib, can help people with advanced lung cancer that has a specific mutation feel better and improve their treatment results.

  Recruiting Phase 1/2 Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT05271916

• Analyzing Drug Resistance in Lung Cancer Immunotherapy

  This study is testing how certain genetic markers in patients with advanced lung cancer might affect their response to immunotherapy treatments.

  Recruiting Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT04977791

• Comparing surgery and radiation for early-stage esophageal cancer

  This study is testing whether surgery or radiation works better for people with early-stage esophageal cancer to help them live longer and have a better quality of life.

  Recruiting Phase 3 Shanghai Chest Hospital · Nanchang, Jiangxi and 5 other locations · NCT04135664

Quick answers

How many clinical trials run by Shanghai Chest Hospital are recruiting right now?

48, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in China (48 trials), France (2 trials), Italy (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 13, Phase 1/2: 3, Phase 3: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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