Exploring the link between psychological distress and treatment outcomes in lung cancer patients

the Association of Psychological Distress in Patients With Advanced Lung Cancer Treated With Immunotherapy or Targeted Therapy

Observational Shanghai Chest Hospital · NCT06218901

This study looks at how stress and emotional struggles affect the success of cancer treatments in people with advanced lung cancer.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years and up
SexAll
SponsorShanghai Chest Hospital Academic / other
Drugs / interventionsimmunotherapy
Locations1 site (Shanghai, Shanghai Municipality)
Trial IDNCT06218901 on ClinicalTrials.gov

What this trial studies

This observational study investigates how psychological distress affects the efficacy and survival of anti-tumor therapies, including immunotherapy and targeted therapy, in patients with advanced lung cancer. It aims to understand the multi-faceted nature of psychological distress and its impact on coping with cancer and treatment. By analyzing the associations between psychological stress and treatment outcomes, the study seeks to identify potential ways to improve patient care and therapeutic effectiveness.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older with a histologically confirmed diagnosis of lung cancer.

Not a fit: Patients who are unwilling to participate in the clinical trial will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment strategies that address psychological distress, enhancing the overall efficacy of cancer therapies for patients.

How similar studies have performed: While the approach of linking psychological distress to treatment outcomes is not novel, previous studies have shown varying degrees of success in understanding its impact on cancer therapies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Histologically proven diagnosis of lung cancer
* 18 years of age or older
* Ability to understand and the willingness to sign a written informed consent document

Exclusion Criteria:

* Not willing to participate in this clinical trial

Where this trial is running

Shanghai, Shanghai Municipality

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lung NeoplasmsPsychological DistressPrognosis FactorsLifestyle, HealthyIMMUNOTHERAPYTargeted Molecular Therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.