Lung cancer screening using low-dose CT scans in high-risk individuals

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of various lung cancer screening strategies, specifically focusing on low-dose computed tomography (LDCT) in high-risk individuals aged 45-75. It aims to validate previous findings that showed a significant increase in early-stage lung cancer detection through LDCT compared to usual care. The study involves recruiting 100,000 participants who will undergo baseline and two biennial LDCT screenings, with follow-up assessments for lung cancer incidence and mortality. Additionally, blood samples will be collected for future research purposes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Eligible participants were those aged 45-75 years, and with either of the following risk factors:

  1. history of cigarette smoking ≥ 20 pack-years, and, if former smokers, had quit within the previous 15 years;
  2. malignant tumors history in immediate family members;
  3. personal cancer history;
  4. professional exposure to carcinogens;
  5. long term exposure to second-hand smoke;
  6. long term exposure to cooking oil fumes.

Exclusion Criteria:

* Had a CT scan of chest within last 12 months
* History of any cancer within 5 years

Where it's running

• Shanghai Chest hospital
  Shanghai, Shanghai Municipality, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.