Analysis and treatment options for thymic cancers

Molecular Landscape Analysis and Treatment Options for Thymic Epithelial Tumors

Observational Shanghai Chest Hospital · NCT05667948

This study is trying to find out how genetic changes in thymic cancers can help doctors create better, personalized treatments for patients.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years and up
SexAll
SponsorShanghai Chest Hospital Academic / other
Drugs / interventionsradiation
Locations1 site (Shanghai, Shanghai Municipality)
Trial IDNCT05667948 on ClinicalTrials.gov

What this trial studies

This observational study focuses on thymic malignancies, which are the most common tumors found in the anterior mediastinum. It aims to create a patient registry to identify genetic alterations in thymic tumors, which could help in predicting responses to novel targeted therapies. By understanding these molecular changes, the study seeks to develop more effective treatment options for patients with thymic cancers. The research emphasizes the importance of individualized treatment approaches based on molecular diagnostics.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older with a histologically proven diagnosis of thymic malignancies.

Not a fit: Patients with thymic malignancies who are under 18 years of age or do not have a confirmed histological diagnosis may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more effective and personalized treatment options for patients with thymic malignancies.

How similar studies have performed: While there is ongoing research in the field of thymic malignancies, this study's specific focus on molecular alterations and individualized treatment is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Histologically proven diagnosis of thymic malignancies
* 18 years of age or older
* Ability to understand and the willingness to sign a written informed consent document

Where this trial is running

Shanghai, Shanghai Municipality

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Thymic Epithelial TumorThymic CarcinomaThymic Cancerthymic malignancythymomachemotherapytargeted therapyimmunotherapy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.