Sponsor or institution
Clinical trials and research at San Jose State University
As of November 12, 2026, Find a Trial lists 29 NIH-funded research projects at this institution, with $5.2 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 29NIH research projects
NIH-funded research (29)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Hormonal limits on heart cell division in mammalian hearts
This grant looks at why adult hearts can’t regrow after injury and explores how hormones, especially thyroid hormone, stop heart cells from dividing to help young hearts regenerate.
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How the cell’s environment affects p53 and PTEN stability and clumping
This project looks at how the inside of cancer cells might push p53 and PTEN to misfold and form clumps, which could drive cancer progression.
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Closed-loop Deep Brain Stimulation for Disrupting Abnormal Brain Signals in Alzheimer’s Disease
This grant funds research to test a smart, responsive brain stimulation approach to help people with Alzheimer’s-related brain changes feel fewer symptoms.
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Diet-Driven Muscle Stem Cell Activation in Fruit-Fly Models
A basic science project aims to understand how diet affects muscle stem cells in a model system and what this could mean for muscle repair and aging in people.
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Understanding Amyloid Fibril Formation in Diseases Using Space-Based Simulations
Researchers will use advanced computer models to study how tiny protein fibers that cause diseases like Alzheimer’s and type 2 diabetes start forming.
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High-Definition 3D Printing Tool for Microfluidics at SJSU
A high-definition 3D printer will help San Jose State University researchers and students quickly build microfluidic devices for biology and biomedical education.
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Caregiver language input during remote book-sharing to help toddlers with cleft lip/palate
This project looks at how the language and gestures used by caregivers during online book-sharing with toddlers who have cleft lip/palate might support the child’s speech and language development.
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Intracellular pH and Cancer Cell Behavior
A cancer-focused project looks at how higher inside-the-cell acidity (pHi) may drive cancer traits by changing key proteins and cell death pathways.
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How a pneumonia toxin damages the lung lining
This project looks at how a toxin made by Streptococcus pneumoniae damages the cells that line the lungs during pneumococcal infection to help people with pneumonia.
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How the front (N-terminal) region of the SIRT1 protein controls its activity
Researchers want to learn how a specific part of the SIRT1 protein changes its activity, which could matter for people with type 2 diabetes or Alzheimer's disease.
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How muscles sense stretch
This research looks at key proteins that let muscle sensors detect stretch to better understand movement and balance problems in conditions like aging, chemotherapy-related nerve damage, and certain genetic movement disorders.
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How Candida biofilms evolve to survive and resist drugs
Researchers are growing Candida glabrata biofilms over many generations to find how they change and become resistant to antifungal treatments, helping people who get fungal infections.
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Understanding How Amyloid Fibrils Form in Diseases Like Alzheimer's and Type 2 Diabetes
This project aims to uncover the mysterious process by which amyloid fibrils, linked to conditions such as Alzheimer's disease and type 2 diabetes, begin to form.
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Adaptive deep brain stimulation to reduce harmful brain rhythms
A computer-guided closed-loop deep brain stimulation approach aims to reduce harmful synchronized brain activity for people with Parkinson's disease and Alzheimer's-related brain rhythm problems.
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How hormones and nerve signals control heart muscle cell growth and renewal
This project looks at how hormone and nerve-related signals after birth influence whether heart muscle cells grow larger or keep dividing, aiming to help people who lose heart muscle after a heart attack.
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How higher acidity inside cells affects cancer behavior
This study is looking at how higher acidity inside cancer cells affects their growth and movement, focusing on a specific protein that might help us understand how these changes could lead to more aggressive cancer behavior, with the hope of finding new ways to treat cancer.
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Understanding how SIRT1 is regulated by its N-terminal region
This study is looking at how a specific part of the SIRT1 protein works and how different compounds, like resveratrol, can change its activity, which could help develop new treatments for conditions like Alzheimer's disease and diabetes.
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Understanding how a bacterial toxin damages lung cells during pneumonia
This study is looking at how a toxin from a bacteria called Streptococcus pneumoniae affects lung cells, with the hope of learning more about how pneumonia damages the lungs and finding better ways to treat it.
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Understanding how muscle sensors respond to stretching
This study is looking at how certain proteins help muscle sensors in our bodies detect stretching, which is important for knowing where our body is and how it moves, and it could help us understand issues with body awareness that some people face as they age or after certain treatments.
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Investigating red blood cell changes in chronic fatigue syndrome
This study is looking at how red blood cells work in people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) to see if there are any differences compared to healthy individuals, which could help improve diagnosis and treatment for the condition.
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Exploring how language affects mental health in young Asian American immigrants
This study looks at how speaking English and feeling connected to their culture affects the mental health of young Asian and Asian American adults who came to the U.S. as kids, especially during tough times like the COVID-19 pandemic.
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Understanding how amyloid fibrils form in diseases like Alzheimer's and diabetes
This study is looking at how certain proteins clump together in the early stages, which is important for understanding diseases like Alzheimer's and type 2 diabetes, and it aims to find new ways to help patients by figuring out how these clumps form in tight spaces.
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Understanding how Candida biofilms adapt to treatment challenges
This study is looking at how a type of fungus called Candida glabrata adapts to tough conditions, which can help us find better treatments for infections, especially for people with weakened immune systems.
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A new microscope for advanced biological imaging
This study is looking to get a new high-tech microscope to help scientists at San José State University see live cells better and faster, which will make their research on health and biology even more effective.
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Understanding how heart cells grow and divide in mammals.
This study looks at how heart muscle cells grow and divide differently in babies compared to adults, and it explores how certain hormones might help the heart heal better after an injury, which could lead to new ways to treat heart failure.
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How environmental changes affect mutations in viruses
This study looks at how quickly changes in the environment, like temperature, can affect the way RNA viruses, such as the bacteriophage ɸ6 Cystovirus, mutate and adapt, which could help us find better ways to treat viral infections.
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Using advanced brain stimulation to improve neural activity in Alzheimer's disease
This study is exploring a new way to use deep brain stimulation for people with Alzheimer's by creating a smart system that automatically adjusts the treatment based on how the brain is doing, which could lead to better results and less need for frequent doctor visits.
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Understanding how the nervous system affects blood pressure in people with autism
This study is looking into why people with Autism Spectrum Disorder often have higher blood pressure and heart problems, and it will measure how their nervous system reacts during exercise to help find ways to manage blood pressure better for them.
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Investigating how surface texture affects blood vessel healing in new materials
This study is looking at how the texture of certain materials used in blood vessel grafts can help them heal better in your body, aiming to make these grafts safer and more effective for patients needing them.
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