Understanding how the nervous system affects blood pressure in people with autism

The Role of Sympathetic Nervous System Activity on Blood Pressure Regulation in Individuals with Autism Spectrum Disorder

['FUNDING_OTHER'] · SAN JOSE STATE UNIVERSITY · NIH-10764239

This study is looking into why people with Autism Spectrum Disorder often have higher blood pressure and heart problems, and it will measure how their nervous system reacts during exercise to help find ways to manage blood pressure better for them.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorSAN JOSE STATE UNIVERSITY (nih funded)
Locations1 site (SAN JOSE, UNITED STATES)
Trial IDNIH-10764239 on ClinicalTrials.gov

What this research studies

This research investigates the reasons behind higher blood pressure and cardiovascular disease rates in individuals with Autism Spectrum Disorder (ASD). It focuses on measuring sympathetic nerve activity directly, which has not been done before in this population. By examining how the nervous system responds during exercise, the study aims to identify the mechanisms that lead to increased blood pressure. The findings could pave the way for future interventions to manage blood pressure in individuals with ASD.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Autism Spectrum Disorder who may experience hypertension or cardiovascular issues.

Not a fit: Patients without a diagnosis of Autism Spectrum Disorder or those who do not have hypertension may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for managing blood pressure and reducing cardiovascular risks in individuals with autism.

How similar studies have performed: While there has been limited research on this topic, the approach of directly measuring sympathetic nerve activity in ASD is novel and has not been extensively tested.

Where this research is happening

SAN JOSE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: cardiovascular disorder, Cardiovascular Diseases

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.