Investigating how surface texture affects blood vessel healing in new materials
Reactive Ion Plasma Treatment of Cardiovascular Biomaterials to Understand the Effect of Nanotopography on Endothelialization
['FUNDING_OTHER'] · SAN JOSE STATE UNIVERSITY · NIH-10671521
This study is looking at how the texture of certain materials used in blood vessel grafts can help them heal better in your body, aiming to make these grafts safer and more effective for patients needing them.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SAN JOSE STATE UNIVERSITY (nih funded) |
| Locations | 1 site (SAN JOSE, UNITED STATES) |
| Trial ID | NIH-10671521 on ClinicalTrials.gov |
What this research studies
This research explores how the surface texture of vascular graft materials influences the healing process of blood vessels. By using a technique called reactive ion plasma treatment, the study aims to improve a specific material known as polyvinyl alcohol (PVA) to enhance its compatibility with the body. The goal is to create vascular grafts that are less likely to fail due to blood clotting or tissue buildup, which are common issues with current synthetic grafts. Patients may benefit from improved graft materials that promote better healing and integration with their own blood vessels.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals requiring vascular grafts, particularly those with conditions affecting blood flow.
Not a fit: Patients who do not require vascular grafts or have contraindications for graft surgery may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective vascular grafts that reduce the risk of complications and improve patient outcomes.
How similar studies have performed: Previous research has shown promise in improving vascular graft materials through surface modifications, indicating potential for success in this approach.
Where this research is happening
SAN JOSE, UNITED STATES
- SAN JOSE STATE UNIVERSITY — SAN JOSE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JURNEY, PATRICK — SAN JOSE STATE UNIVERSITY
- Study coordinator: JURNEY, PATRICK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.