Sponsor or institution
Clinical trials and research at Rhode Island Hospital
As of November 12, 2026, Find a Trial lists 22 clinical trials run by Rhode Island Hospital that are recruiting, at sites in 2 countries (most in United States (22), Puerto Rico (2)). By phase: Early Phase 1 (1), Phase 2/3 (1), Phase 1/2 (1), Phase 4 (1). There are also 171 NIH-funded research projects at this institution, with $85.2 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 22Clinical trials
- 171NIH research projects
- 2Countries
Newest trials
All recruiting trials (22)
-
Personalized Addiction Treatment Enhancement for Opioid Use Disorder
A digital platform run by peer recovery supporters will be tested to help adults with opioid use disorder who are on buprenorphine or methadone stay in treatment and improve outcomes.
-
Connecting Loved Ones to Support and Empower Recovery
A web-based program called KulaMind-Recovery tests whether guided online training, one-on-one coaching, and a community forum help loved ones support someone with a substance use disorder.
-
Intraoperative Music Therapy for TAVR Patients
This study tests whether listening to relaxing music during a transcatheter aortic valve replacement can reduce anxiety for patients.
-
Suprainguinal fascia iliaca block with or without dexmedetomidine for hip replacement pain
This trial will test whether adding dexmedetomidine to ropivacaine in a suprainguinal fascia iliaca nerve block helps control pain and delay the first request for pain medication after elective hip replacement.
-
Video support for teens and families after a traumatic injury
This project tests short video interventions for hospitalized teens and their parents to see if they reduce PTSD symptoms and future substance use after a traumatic injury.
-
Peroneal nerve stimulation for restless legs during pregnancy
This pilot will test whether a wearable TOMAC peroneal nerve stimulator can reduce restless legs symptoms and improve sleep for pregnant people.
-
Adaptive family program to boost follow-up mental health care after an ED visit
This project will test a brief, family-based adaptive program to help youth ages 8–17 with suicidal or self-injurious behavior connect to and keep attending community mental health care after an emergency department visit.
-
Helping adolescent males talk with trusted adults about sexual health and HIV prevention
This project will try a program to help 14–17-year-old males who have sex with males talk with trusted adults, find a trusted adult if needed, and learn ways to protect their sexual health while keeping privacy.
-
SIESTA: A sleep hygiene program for urban Latino middle schoolers
This program tests whether a culturally tailored, school-based sleep hygiene intervention (SIESTA) helps urban Latino middle schoolers ages 11–13 sleep longer and improve sleep habits compared with a health education control.
-
Neurobehavioral Therapy for treating Functional Neurological Disorder
This study is testing whether Neurobehavioral Therapy can help adults with motor functional neurological disorder feel better when combined with regular medical care.
-
Program to prevent peer aggression and dating violence in preteens receiving mental health services
This study is testing a new program to see if it can help preteens in mental health treatment reduce bullying and dating violence by teaching them social skills and how to manage their emotions.
-
Testing a sleep intervention for expectant and new mothers
This study is testing a new sleep program for expectant and new mothers to see if it can help them get better sleep during and after pregnancy.
-
Using Irrisept Solution to Prevent Infections After Spine Surgery
This study is testing if using Irrisept instead of regular saline can help prevent infections after spine surgery for adults with different spinal conditions.
-
Testing higher doses of buprenorphine for treating opioid use disorder
This study tests if a higher daily dose of buprenorphine can help people with opioid use disorder, especially those who have used fentanyl, feel better and stay in treatment longer compared to the standard dose.
-
Program to improve asthma management in children in San Juan, Puerto Rico
This study is testing a new program to help children in San Juan, Puerto Rico, manage their asthma better and improve their quality of life.
-
Botulinum toxin injection for thumb arthritis pain
This study is testing if botulinum toxin injections can help relieve thumb arthritis pain for people who haven't found relief with other treatments.
-
A mobile game to help young people stick to their HIV prevention medication
This study tests a mobile game called Viral Combat to see if it helps young people aged 15-34 stick to their HIV prevention medication better than a different game.
-
Effects of a Low Glycemic Load Diet on Diabetes and Body Composition in Adults with Cystic Fibrosis
This study is testing if a low glycemic load diet can help adults with cystic fibrosis-related diabetes manage their blood sugar and improve their overall health.
-
Supplemental vitamin A and nicotinamide for kidney transplant recipients at high risk of skin cancer
This pilot will test whether taking oral nicotinamide and vitamin A is safe and doable for kidney transplant recipients who have had recent skin cancers.
-
Evaluating sepsis treatment methods in emergency departments
This study tests two different treatment plans for sepsis in emergency rooms to see which one helps patients survive and avoid breathing problems better.
-
Custom pillow improves sleep quality for rotator cuff injury patients
This study tests if using a special pillow can help people with rotator cuff injuries sleep better.
-
Using Treprostinil to Reduce Kidney Injury During Transplantation
This study is testing if a medication called treprostinil can help protect the kidneys of adults getting a transplant from deceased donors and improve their recovery.
NIH-funded research (newest 40 of 171)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
-
How often to treat schistosomiasis to protect the liver
A randomized trial will test different frequencies ofPraziquantel treatment to prevent liver damage in people aged 15–40 with schistosomiasis in Uganda.
-
Technology-assisted overdose response tools for Rhode Island communities
A Rhode Island hospital-led project will test easy-to-use, tech-enabled tools (like wall buttons, wearable sensors, and a mobile app) to help detect and respond to overdoses in real-world settings.
-
Mindfulness training to lower cardiovascular risk for moms and babies during pregnancy
A mindfulness program is being tested during pregnancy to help prevent high blood pressure and heart problems for mothers and their babies.
-
Point-of-care test to spot risk of liver scarring from Schistosoma japonicum
This project aims to develop a simple clinic test to find people with S. japonicum infection who are likely to develop worsening liver scarring so they can get treatment earlier.
-
Mobile phone-based screening for anemia in young children in western Kenya
A low-cost, phone-based screening approach helps identify anemia in young children in western Kenya so they can get timely care.
-
Role of lactate transporters in lung scarring
Aims to see if blocking lactate transporters can slow or stop scar-forming cells from thickening the lungs in people with fibrotic lung disease.
-
Understanding what leads to heavy drinking in bisexual and heterosexual women who have experienced sexual assault
This grant explores why heavy drinking happens at specific moments for bisexual and heterosexual women with sexual assault histories, with the goal of finding ways to help reduce risky drinking.
-
Emotion Regulation Help for Youth in Child Welfare to Prevent Substance Use
A tablet-based program helps early adolescents in the child welfare system learn emotion regulation skills to reduce future substance use.
-
DTX3L in Sepsis: Protecting the heart and metabolism with gene editing
Aims to understand how a muscle protein called DTX3L affects heart function and insulin resistance during severe infection (sepsis) and whether targeting it could help people with sepsis.
-
Pediatric Emergency Department Family Navigation to Connect Youth with Suicide and Self-Injury Care
A program helps families navigate emergency department visits for youth with suicide- or self-injury-related concerns to connect them with mental health care.
-
Understanding and reducing diagnostic errors in US emergency rooms
A big study using national data will look at how often misdiagnoses happen in US emergency departments and how those errors affect patients and costs.
-
Treating schistosomiasis-related liver scarring: a new approach for people ages 15–40
A large trial in Uganda will test different schedules of praziquantel to see if more frequent treatment can prevent liver scarring from schistosomiasis and improve outcomes for teens, young adults, and adults.
-
PR-AIR: A program to reduce pediatric asthma disparities in Puerto Rico
Aimed at Puerto Rican children with asthma, this project tests home and school–based strategies to reduce asthma burden in San Juan through community involvement and tailored implementation.
-
Police pathways to treatment and safety for people who use drugs
A study in two U.S. cities explores police-assisted diversion to connect people who use drugs with treatment and services instead of arrest.
-
HIV Testing in Emergency Rooms to Reach More People in Kenya and Beyond
A program will test if improving emergency department processes can help more people with HIV get tested, especially groups at higher risk.
-
SHE-OUD: a quick, private screen-and-help program for women in opioid treatment
A brief, computer-based screening and intervention is tested to help women with opioid use disorder who have experienced sexual violence and PTSD, aiming to improve their treatment outcomes.
-
Adolescents, Social Media, and Teen Mental Health
A study with teens ages 13-16 will look at how social media use relates to feelings of anxiety and depression over time.
-
Community Engaged Research Core for Opioid Use Disorder and Overdose
A program to support early-career researchers studying opioid use disorder and overdose by strengthening community engagement and research infrastructure.
-
Translational and Transformative Research for Opioid Addiction and Overdose
A translational research program in Rhode Island aims to speed new ideas for opioid addiction and overdose care from bench to practice, benefiting adults across the country.
-
Data and Methods Core for Opioids and Overdose Research
A centralized resource helps researchers study opioids and overdose by providing design, data management, biostatistics, and data-linking support.
-
Administrative Core for Opioids and Overdose COBRE
A grant that funds leadership and coordination to help researchers study opioid use disorder and overdose prevention.
-
COBRE Center on Opioids and Overdose (patient-facing summary)
A funded program at Rhode Island Hospital to support researchers studying why people become vulnerable to opioid misuse and overdose, and to develop better ways to prevent and treat them.
-
Mobile phone screening for anemia in young children in western Kenya
A low-cost, phone-based screening approach is tested to identify anemia in young children in western Kenya so they can get timely treatment.
-
Blocking HDAC6 to protect kidneys during cisplatin chemotherapy
Aimed at preventing kidney injury from cisplatin cancer treatment by blocking HDAC6, with the hope of keeping kidneys healthy during chemotherapy.
-
Rhode Island Child Clinical Trials Collaborative for Kids with ASD and Related Conditions
A pediatric clinical trials network in Rhode Island coordinates and conducts child-focused studies to improve care for autism and related health issues.
-
Mobile phone screening for anemia in young children in western Kenya
This project uses a mobile-phone tool to find anemia in young children in western Kenya so they can get follow-up testing and care.
-
Enhancing a Free Hematology/Oncology Drug Knowledgebase
A project to expand and improve HemOnc.org, a free online resource with detailed information about cancer drugs and regimens for clinicians and researchers.
-
Low-threshold hepatitis C treatment in jail to help people released back to the community
A patient-friendly plan to test a simple, quick hepatitis C treatment in jail for people who use drugs, with care that continues after release.
-
Novel antimalarial drugs that target PfGARP to treat severe malaria
A new class of drugs is being explored to treat severe malaria by targeting PfGARP, a parasite protein, with the aim of helping children in malaria-endemic regions.
-
Environmental enteric dysfunction and anemia in young children with gut infections
A study in young children with gut parasites will look at how gut problems may affect drug absorption and cause anemia.
-
Understanding lung problems after TB in teens
This project looks at why some teenagers who were treated for TB still have breathing problems and how to prevent or treat this later.
-
Ebola Virus Disease Treatment: adjunctive GI therapies to improve survival
A project using data from past Ebola outbreaks to see if common GI medicines like omeprazole, metronidazole, and albendazole could help reduce death rates.
-
Pharmacology Core to speed safer, smarter drug dosing for infectious diseases
A Pharmacology Core at Rhode Island Hospital will help turn early drug ideas into safer, more effective dosing for infectious diseases.
-
Administrative Core for Pathogens of Human Significance COBRE
A hospital-based program is creating a hub to mentor researchers and manage funds to tackle serious infections like tuberculosis, malaria, schistosomiasis, and Ebola, with a focus on improving care for children.
-
Pathogens of Human Significance: Translational COBRE Center
A COBRE center at Rhode Island Hospital aims to reduce illness and deaths from malaria, tuberculosis, schistosomiasis, and Ebola by supporting researchers and building translational pathways.
-
Understanding how to apply sepsis care guidelines in ICU patients with respiratory failure
A patient-friendly look at how hospitals can best use sepsis care bundles to save lives for people with breathing problems in the ICU.
-
Mobile phone screening for anemia in young children in western Kenya
Uses a mobile phone approach to find anemia in young children in western Kenya.
-
Autoantibodies and immune suppression in sepsis and ARDS
A human-focused study to understand how autoimmune antibodies develop during sepsis and ARDS and how they affect immune function and infections.
-
Pre-intubation checklist to make emergency breathing tube placement safer for injured children
Using a pre-intubation checklist and support tools to help emergency teams place breathing tubes more safely in children after traumatic injury.
-
Coronary blood vessel resilience through mitochondrial antioxidant therapy
Aims to see if boosting mitochondrial defenses in heart blood vessel cells helps them survive and grow during low-oxygen heart attacks, potentially aiding heart recovery.
Quick answers
How many clinical trials run by Rhode Island Hospital are recruiting right now?
22, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (22 trials), Puerto Rico (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Early Phase 1: 1, Phase 2/3: 1, Phase 1/2: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.