NIH-funded research R01 grant

PR-AIR: A program to reduce pediatric asthma disparities in Puerto Rico

Official title: Puerto Rico Asthma Integrated Response Program (PR-AIR)

Funded at Rhode Island Hospital · NIH-11418024 · Data updated 2026-11-12

Aimed at Puerto Rican children with asthma, this project tests home and school–based strategies to reduce asthma burden in San Juan through community involvement and tailored implementation.

More Asthma research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRhode Island Hospital
NIH-funded
Lab location1 site (Providence, United States)
Project startSeptember 15, 2022
Project endJuly 31, 2027
Funding year2026
Award (this year)$692,502
NIH project number5R01HL159701-05
Project IDNIH-11418024 on NIH RePORTER

Who could benefit from this research

Could help

Children with asthma living in San Juan, PR, and their families, plus school staff and healthcare providers engaged in their care.

Less likely to help

Families not in the participating 12 high-burden communities may not directly benefit during the study.

What this research studies

This funded project partners with families, schools, and healthcare providers in San Juan to adapt proven asthma interventions for Puerto Rico. It uses a phased approach, beginning with community input and interviews to tailor methods, followed by a hybrid effectiveness-implementation trial comparing virtual and in-person delivery. The study will roll out the program sequentially to 12 high-burden communities using a cluster-randomized stepped-wedge design. The goal is to improve asthma management and outcomes by improving home, school, and clinician communication and by identifying barriers and facilitators to real-world uptake. Participation would involve families, caregivers, school staff, and healthcare teams across participating communities.

Why it matters

Potential benefit: If successful, PR-AIR could reduce asthma symptoms and healthcare visits for Puerto Rican children through better home-school-clinic coordination.

How similar studies have gone: Previous similar implementation efforts in other communities show promise for improving management when interventions are adapted to local contexts.

Where this research is happening

  • Rhode Island Hospital
    Providence, United States
    Active

Researchers

  • Principal investigator: Koinis Mitchell, Daphne — Rhode Island Hospital
  • Study coordinator: Koinis Mitchell, Daphne

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.