Sponsor or institution
Clinical trials and research at North Carolina State University Raleigh
As of November 12, 2026, Find a Trial lists 228 NIH-funded research projects at this institution, with $115.3 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 228NIH research projects
NIH-funded research (newest 40 of 228)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Brewing anti-toxin drugs using probiotic yeast
A studying team will develop probiotic yeast–based anti-toxin drugs to help treat gut bacterial infections and reduce antibiotic-related complications.
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Small Ruminant Therapeutic Center to Speed Safe Drugs for Sheep and Goats
A pilot project at a university will help scientists and veterinarians speed up and improve how drugs are tested and approved for sheep and goats.
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Metabolic effects of PFAS exposure in the Cape Fear Basin (GenX Exposure Study)
This NIH grant studies how PFAS chemicals in drinking water may affect metabolism and weight-related health in adults and children living along the Cape Fear River.
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Understanding how Fe/2OG enzymes make pharmacophores like cyclopropane, aziridine, and isonitrile groups
A research project at a university aims to uncover how nonheme-iron enzymes create key drug-building rings and groups to help develop better biocatalysts and medicines.
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Hemostatic B-knob Microgels for Pediatric Bleeding
A kid-friendly hemostatic therapy using age-tuned microgels to stop dangerous bleeding after injury in children.
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How cyanotoxins may harm nerve cells in ALS
This grant studies how shared toxins from cyanobacteria might worsen nerve damage in people with ALS.
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Copper control tools to study brain health and diseases
A doctor-scientist team is making precise chemical tools to control copper in the body, with a focus on brain conditions like Alzheimer's disease.
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Transforming Elderly and Rare Cancers Through Smart Information Sharing in Trials
This grant develops new trial designs and data methods to make cancer trials more reliable and generalizable for elderly patients and rare cancers.
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Posttranscriptional Regulation of ozone-induced lung inflammation
This research explores how the body’s own regulators control harmful lung inflammation caused by ozone exposure, with potential implications for treating people with respiratory conditions.
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Pathway clues for how genes and environment interact in asthma and related diseases
This project looks at how variations in the AHR gene and related genes interact with everyday environmental exposures to influence diseases like asthma, using a large human cohort to map these interactions.
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Intravascular Ultrasound Tissue Ablation for Restenosis
A new catheter-based ultrasound approach aims to safely remove excess tissue inside stents to prevent repeat vessel narrowing after a stent procedure.
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Cultivation and Genomic Study of Orientia in the US
A patient-facing overview of a study to understand the bacteria Orientia that causes scrub typhus, how it grows in the US, and its genetic makeup.
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Trace metals and liver disease: how environmental exposure may shape liver health
This project looks at whether long-term exposure to metals in the environment is linked to worsening liver disease in people from the Southern U.S.
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Bile-salt helpers: how gut enzymes may limit C. difficile infection
A doctor-research team is studying gut bacteria enzymes that attach amino acids to bile acids to see if they can reduce C. difficile growth and disease.
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Monitoring antibiotic resistance in bacteria from retail meats and seafood
A North Carolina project will track how common drug-resistant bacteria from everyday foods like pork, chicken, beef, and seafood are, to protect public health.
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A Big Database that Links Chemicals, Genes, and Diseases to Help Cancer Patients
A public database collects and links information about chemicals, genes, and diseases to help researchers understand cancer and other environmentally influenced illnesses.
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Graft Remodeling and Joint Degeneration after ACL Reconstruction in the Growing Knee Joint
This grant focuses on how ACL reconstruction in growing kids and teens affects knee grafts and long-term joint health.
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Neurodevelopmental effects of flame retardant exposure (in humans/animals)
Flame retardants given during development may change brain development and social anxiety, with stronger effects seen in females, using animal models that mimic human social behavior.
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Imaging and data platform to map brain glial development
A new imaging and data platform will map glial development in the brain at subcellular detail to better understand diseases like Alexander disease and Alzheimer’s-related changes.
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Spine-hip exoskeletons with smart control to ease lower back pain
A team is testing a spine-hip soft exoskeleton with learning-based control to reduce strain and injury risk for workers who lift heavy loads.
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Synchronous Dyadic Monitoring of People and Dogs to Understand and Improve Animal-Assisted Interventions
A research project will test a wearable sensor system to track both a cancer patient and a therapy dog during animal-assisted programs to learn how their bodies respond together in real time.
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Antibiotic resistance tracking in bacteria from North Carolina meat and seafood
This project tracks whether bacteria found in retail meat and seafood in North Carolina are resistant to antibiotics, to help protect people who eat these foods.
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Toxic metals and liver disease risk in adults with diabetes
This grant explores how exposure to harmful metals may raise the risk of fatty liver disease in adults with type 2 diabetes or related metabolic problems.
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Switchable fluorescent tools for ultra-precise imaging of cell biology
A scientist at NC State is developing smart fluorophores that can switch on and off and work together with advanced imaging to study how molecules behave inside living cells.
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Personalized RL-powered Prosthetic Leg for Amputees
A new approach uses reinforcement learning to tailor powered leg prostheses to each patient, helping people with leg amputations walk more efficiently and comfortably.
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C/EBPβ and the skin’s immune alarms in autoimmune disease
A study in people and models to understand how skin cells decide to die when stressed or damaged, which may influence autoimmune diseases.
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Predicting harmful algal toxin risks in coastal waters and seafood
This project builds computer models to predict when and where algal toxins may contaminate coastal water and oysters so coastal communities and seafood consumers can stay safer.
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How algal microcystin mixtures may affect liver disease and cancer risk.
This project looks at whether mixtures of microcystin toxins from harmful algal blooms increase the chance of fatty liver disease and liver cancer for people living near affected waterways.
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Algal toxins in oysters and blue crabs in coastal North Carolina waters
This project looks at how algal poisons called microcystins get into oysters and blue crabs so people who eat local seafood can be safer.
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Community partnership to monitor harmful algal blooms
A program to help coastal residents, anglers, and boaters collect and share local data on harmful algal blooms so their health and environment are better protected.
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NC Coastal Algae, People, and Environment — tracking harmful algal toxins and health risks
This project looks at how harmful algal blooms and their toxins in North Carolina coastal waters might affect local people and the safety of seafood.
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Restoring daily balance with smarter powered ankle prostheses
Aims to improve balance and reduce falls for people with lower-limb amputations by making powered ankle prostheses smarter and easier to control.
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Quantitative Ultrasound for Lung Diseases in People
A new ultrasound approach to measure how bad heart- or fibrosis-related lung problems are, using real-time, noninvasive imaging in people.
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New methods to create high-performance aptamers for real-time sensing in the body
A new NIH-funded project will develop improved DNA-based aptamers that can sense small molecules inside the body and report their presence in real time.
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Posttranscriptional regulation of allergic inflammation
A small NIH-funded project aims to understand how a specific cellular regulator helps control allergic lung inflammation in people with asthma.
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Improving Microbiome Measurement with Better Computational Methods
A researcher team is developing better computer-based ways to measure and interpret the microbes living in the human body, aiming to help doctors understand health issues linked to the microbiome.
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Understanding How Iron-Dependent Enzymes Make Pharmacophores in Drugs
Researchers are studying how certain iron-loving enzymes make small, drug-like building blocks to help design better medicines.
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Epigenetic networks guiding endometrial function in fertility
A patient-focused look at how the uterus’ epigenetic switches may affect implantation and pregnancy maintenance in women facing infertility and recurrent pregnancy loss.
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Metformin’s effects on liver fat through the small intestine
A new NIH grant is exploring how metformin changes fat metabolism in the liver and whether the small intestine plays a key role, with potential implications for treating fatty liver disease.
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Oral mucosal vaccination using a new floss-based method
A new floss-based approach aims to teach the immune system through the mouth to help protect against infections like HIV and flu.
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