A Big Database that Links Chemicals, Genes, and Diseases to Help Cancer Patients
Official title: Comparative Toxicogenomics Database (CTD)
Funded at North Carolina State University Raleigh · NIH-11422610 · Data updated 2026-11-12
A public database collects and links information about chemicals, genes, and diseases to help researchers understand cancer and other environmentally influenced illnesses.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project start | September 1, 2021 |
| Project end | August 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $2,272,945 |
| NIH project number | 2U24ES033155-06 |
| Project ID | NIH-11422610 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals whose cancers or environmental exposures could be better understood through research that uses CTD-linked data and findings.
✕Less likely to help
Patients not directly involved in the data aspects of this database may not experience immediate benefits.
What this research studies
This project maintains and expands CTD, a public resource that curates chemical–gene–disease relationships and exposure data to help scientists interpret environmental factors in disease. By integrating diverse data and creating user-friendly tools, it supports research into how environmental exposures influence cancer and other health conditions. Patients may benefit indirectly as researchers use CTD to design better studies and identify potential targets for treatment and prevention. The effort combines literature curation with analytical and visualization tools to reveal complex connections between chemicals and health outcomes.
Why it matters
Potential benefit: If successful, the work could accelerate discovery of how environmental factors contribute to cancer and other diseases, guiding prevention and treatment strategies.
How similar studies have gone: Similar large-scale data curation efforts have led to meaningful insights, and CTD has a track record of contributing valuable connections for researchers.
Where this research is happening
-
North Carolina State University Raleigh
Raleigh, United States Active
Researchers
- Principal investigator: Mattingly, Carolyn J. — North Carolina State University Raleigh
- Study coordinator: Mattingly, Carolyn J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.