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Clinical trials and research at Nemours Children's Clinic

• 23Clinical trials
• 8NIH research projects
• 2Countries

Newest trials

All recruiting trials (23)

• Pacifier-Activated Lullaby to support oral feeding in preterm infants

  This study tests whether a pacifier-activated lullaby system helps preterm babies move from tube feeding to feeding by mouth.

  Recruiting Nemours Children's Clinic · Orlando, Florida · NCT07819734

• Toolkits to help providers deliver Diabetes Coaching to adolescents with Type 1 diabetes

  This study tests whether groups of implementation tools can help pediatric diabetes and psychology teams at a Delaware hospital deliver Diabetes Coaching to more families.

  Recruiting Nemours Children's Clinic · Wilmington, Delaware · NCT07766811

• Lidocaine During Surgery to See If It Lowers Opioid Use in Kids with Arm Fractures

  In children aged 3–18 having surgery for upper-extremity fractures, this study tests whether giving IV lidocaine during the operation reduces the amount of opioid pain medicine needed after surgery.

  Recruiting Phase 4 Nemours Children's Clinic · Wilmington, Delaware · NCT07552766

• Ultrasound to find elbow fractures in children

  This trial tests whether using bedside ultrasound instead of X-rays helps children who come to the ER with elbow pain.

  Recruiting Nemours Children's Clinic · Orlando, Florida · NCT07212036

• GLP-1 medication effects on reproductive hormones in obese teenage girls with PCOS

  We will test whether GLP-1 medications are linked to changes in reproductive hormones and menstrual cycles in obese adolescent girls with PCOS.

  Recruiting Nemours Children's Clinic · Jacksonville, Florida · NCT07169136

• Auryzon EAR 2.0 to shape cartilage for ear reconstruction

  This test will try the Auryzon EAR 2.0 device to shape rib cartilage and help surgeons build anatomically accurate ears for children and young adults (ages 5–20) with microtia or other ear deformities.

  Recruiting Nemours Children's Clinic · Orlando, Florida · NCT07154667

• Understanding how genetics affect bronchodilator response in children with bronchiolitis

  This study is testing how genetics might affect how well bronchodilator treatments work for young children with bronchiolitis.

  Recruiting Phase 3 Nemours Children's Clinic · Orlando, Florida · NCT06946264

• Improving Sleep, Weight, and Eating in Teens With Obesity

  This study tests whether a 16-week remote lifestyle and sleep program can help teens with overweight or obesity lose weight and improve sleep and eating habits.

  Recruiting Nemours Children's Clinic · Wilmington, Delaware · NCT06745570

• Evaluating vocal fold motion in children on noninvasive ventilation

  This study is testing if using ultrasound can safely check how well the vocal folds are moving in kids on noninvasive ventilation in the ICU compared to a standard method that might be riskier.

  Recruiting Nemours Children's Clinic · Queens, New York · NCT06406725

• Laser hair removal to prevent pilonidal disease from coming back in young people with darker skin

  This project will test whether laser hair removal of the buttock crease helps prevent pilonidal disease from returning in teens and young adults with darker skin tones.

  Recruiting Nemours Children's Clinic · Wilmington, Delaware · NCT06406621

• Comparing umbilical cord milking and early cord clamping for preterm infants

  This study is testing if milking the umbilical cord instead of clamping it right away can help save the lives of preterm babies born between 30 and 34 weeks who need immediate care.

  Recruiting at 3 sites Nemours Children's Clinic · Belagavi, Karnataka and 8 other locations · NCT06240715

• Transdisciplinary care for young adults with type 1 diabetes

  This study tests a new way of caring for young adults with type 1 diabetes to see if it helps them manage their health and well-being better as they move from pediatric to adult care.

  Recruiting at 2 sites Nemours Children's Clinic · Wilmington, Delaware and 1 other locations · NCT06172166

• An acceptance-based healthy lifestyle program for overweight adolescent girls

  This study is testing a new healthy lifestyle program that helps overweight girls aged 14-19 learn to manage their weight and improve their health compared to a regular health education class.

  Recruiting Nemours Children's Clinic · Philadelphia, Pennsylvania · NCT06147973

• Improving access to advanced diabetes technology for children with Type 1 Diabetes

  This study is testing if giving advanced diabetes technology to children and teens with Type 1 Diabetes from lower-income backgrounds can help them manage their condition better.

  Recruiting Nemours Children's Clinic · Jacksonville, Florida and 1 other locations · NCT05849753

• Improving digital health tools for treating bulimia and binge eating disorders

  This study is testing different ways to use digital tools alongside therapy to see which methods help people with bulimia and binge eating disorder the most.

  Recruiting Nemours Children's Clinic · Wilmington, Delaware · NCT05473013

• Helping young people with sickle cell disease make treatment decisions

  This study is testing a new way to help young people with sickle cell disease and their caregivers make better treatment decisions by using virtual reality alongside regular education materials.

  Recruiting Nemours Children's Clinic · Wilmington, Delaware · NCT05383911

• eHealth support for parents of children with cancer

  This study is testing a new online support program for parents of children with cancer to see if it can help them feel less stressed and more able to cope.

  Recruiting Nemours Children's Clinic · Los Angeles, California and 2 other locations · NCT05294302

• Non-invasive assessment of Morquio A syndrome

  This study is trying to find a simple way to check how Morquio A syndrome affects patients' bones and overall health, so we can better understand the disease and help improve treatments.

  Recruiting Nemours Children's Clinic · Wilmington, Delaware · NCT05284006

• Program to help families manage diabetes distress in children

  This study is testing a new program to help families of school-age children with Type 1 Diabetes manage stress related to the condition and see if it improves their health.

  Recruiting at 2 sites Nemours Children's Clinic · Jacksonville, Florida and 1 other locations · NCT05268250

• Impact of Body Composition on Feeding in Large for Gestational Age Infants

  This study is testing if a special feeding plan based on body composition can help Large for Gestational Age infants with feeding difficulties.

  Recruiting at 2 sites Nemours Children's Clinic · Orlando, Florida and 1 other locations · NCT04599010

• Registry for individuals with Rhizomelic Chondrodysplasia Punctata

  This study is collecting medical information from people with Rhizomelic Chondrodysplasia Punctata to see if it can help find ways to improve their health and quality of life.

  Recruiting Nemours Children's Clinic · Wilmington, Delaware · NCT04569162

• Registry for individuals with microcephalic primordial dwarfism

  This study is collecting information about people with microcephalic primordial dwarfism to better understand their conditions and improve their care.

  Recruiting Nemours Children's Clinic · Wilmington, Delaware · NCT04569149

• Evaluation of a new non-invasive respiratory monitor for children

  This study tests a new breathing monitor for kids to see if it works better than an older model by comparing how well it tracks their breathing.

  Recruiting Nemours Children's Clinic · Wilmington, Delaware · NCT02851043

NIH-funded research (8)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Brain changes in young children with new-onset Type 1 diabetes

  This study follows young children recently diagnosed with Type 1 diabetes to understand how the condition affects their brain and what factors might protect or increase risk for learning and behavior problems.

  NIH research Nemours Children's Clinic · Jacksonville, United States · NIH-11384687

• How new-onset type 1 diabetes affects the developing brain in young children

  This project follows children newly diagnosed with type 1 diabetes to track brain development, thinking skills, and blood sugar patterns over time.

  NIH research Nemours Children's Clinic · Jacksonville, United States · NIH-11168763

• Understanding how young adults adapt to and manage chronic pain

  This study is looking at how young people with ongoing pain can better handle their discomfort and thrive as they grow up, by exploring what helps them stay strong and healthy during this challenging time.

  NIH research Nemours Children's Clinic · Jacksonville, United States · NIH-11074138

• Impact of new onset type 1 diabetes on young children's brain health

  This study is looking at how starting type 1 diabetes might change the way children's brains develop from ages 4 to 10, and it’s for kids with diabetes and their families to help understand how managing blood sugar can affect thinking and feelings over time.

  NIH research Nemours Children's Clinic · Jacksonville, United States · NIH-10974088

• A program to help school-age children with diabetes and their families manage stress related to the condition.

  This study is testing a new program called Remedy to Diabetes Distress (R2D2) to help school-age kids with type 1 diabetes and their families manage the stress that comes with it, making it easier for everyone to take care of their health together.

  NIH research Nemours Children's Clinic · Jacksonville, United States · NIH-10896468

• Using home videos to help parents manage their children's fear of low blood sugar.

  This study is designed for parents of young kids with type 1 diabetes who worry a lot about low blood sugar; it offers a friendly video program that teaches helpful strategies to manage those fears and support better blood sugar control for their children.

  NIH research Nemours Children's Clinic · Jacksonville, United States · NIH-10598510

• Using behavioral economics to help teens with diabetes manage their insulin use

  This study is looking to help teenagers with type 1 diabetes manage their insulin better by using fun rewards to encourage them to take their insulin every day, making it easier for them to keep their blood sugar levels in check.

  NIH research Nemours Children's Clinic · Jacksonville, United States · NIH-10597657

• Improving asthma treatment adherence in young people using telehealth.

  This study is looking to help young people aged 14 to 30 with asthma stick to their medication by using video calls and handy tools to track their inhaler use, making it easier and more personal for them to manage their health over a year.

  NIH research Nemours Children's Clinic · Jacksonville, United States · NIH-10466763

Quick answers

How many clinical trials run by Nemours Children's Clinic are recruiting right now?

23, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (22 trials), India (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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