An acceptance-based healthy lifestyle program for overweight adolescent girls

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of an acceptance-based healthy lifestyle intervention compared to a traditional health education program for adolescent girls aged 14-19 who are overweight or obese. Participants will engage in a 6-month program that includes both in-person and remote group sessions, focusing on self-regulation skills, mindfulness, and adaptive responses to unhealthy cues. The study will assess various health metrics, including weight, body composition, and psychological factors, to determine the intervention's impact on weight loss and overall health. The trial specifically targets diverse populations, including those from racial and ethnic minority backgrounds.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Ages 14-19
* Gender identification as girl
* BMI percentile ≥ 85th percentile for sex-and-age

Exclusion Criteria:

* Experience of weight loss of ≥5% of body weight in the past 6 months for any reason except post-partum weight loss
* Having recently begun or changed the dosage of any medication known to affect appetite or body composition within the last 3 months
* Plans to move out of the area within the next year
* Active cancer or cancer requiring treatment in the past 2 years (except non-melanoma skin cancer)
* Active or chronic infections (e.g., HIV or TB)
* Active cardiovascular disease or event including hospitalization or therapeutic procedures for treatment of heart disease in the past 6 months
* Active kidney disease
* History of bariatric surgery
* Lung disease: chronic obstructive airway disease requiring use of oxygen (e.g., emphysema or chronic bronchitis)
* Diagnosed diabetes (type 1 or 2)
* Any condition prohibiting physical activity
* Diagnosis of an eating disorder
* Have a mental handicap or are currently experiencing other severe psychopathology that would limit their ability to engage in the treatment program (e.g., severe depression, active psychotic disorder)
* Recent or ongoing problem with drug abuse, alcohol abuse, or addiction
* Currently pregnant or less than 3 months post-partum
* Anticipation of a possible pregnancy in the next year
* Unwillingness to report possible or confirmed pregnancies promptly during the course of the trial

Where it's running

• Drexel University
  Philadelphia, Pennsylvania, United States Recruiting

Study contacts

• Principal investigator: Stephanie Manasse, PhD — Drexel University
• Study coordinator: Stephanie Manasse, PhD
• Email: smm522@drexel.edu
• Phone: 215-553-7157

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.