Impact of new onset type 1 diabetes on young children's brain health

Cognitive, structural and functional impact of new onset type 1 diabetes on the brain of young children: Understanding risks and protective factors

NIH-funded research Nemours Children's Clinic · NIH-10974088

This study is looking at how starting type 1 diabetes might change the way children's brains develop from ages 4 to 10, and it’s for kids with diabetes and their families to help understand how managing blood sugar can affect thinking and feelings over time.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionNemours Children's Clinic NIH-funded
Lab location1 site (Jacksonville, United States)
Project IDNIH-10974088 on NIH RePORTER

What this research studies

This research investigates how new onset type 1 diabetes affects the brain development of children aged 4 to 10 years. By using advanced brain imaging techniques and neurocognitive assessments, the study aims to identify changes in brain structure and function in children with diabetes compared to their healthy peers. The research will also explore the effects of blood glucose management on cognitive and psychosocial outcomes over time. This longitudinal study will include a diverse group of children to understand the broader implications of diabetes on brain health.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 4 to 10 years who have recently been diagnosed with type 1 diabetes.

Not a fit: Patients who are older than 10 years or those with diabetes for an extended period may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management strategies for cognitive and emotional challenges faced by children with type 1 diabetes.

How similar studies have performed: Previous research has shown significant impacts of diabetes on brain health in children, suggesting that this study's approach is built on established findings.

Where this research is happening

Jacksonville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.