The link between urine cadmium levels and bone health in older adults
Urine cadmium and risk of fracture and bone loss
This study is looking at how cadmium in urine might affect bone health and increase the risk of fractures in older adults, and it will track participants over 20 years to see how their bones change over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project ID | NIH-11182199 on NIH RePORTER |
What this research studies
This research investigates how levels of cadmium found in urine may affect bone health, particularly focusing on the risk of fractures and bone loss in older adults. By analyzing existing data from two major osteoporosis studies, the research aims to understand the long-term effects of cadmium exposure on bone density and overall skeletal health. Participants will be monitored over a period of up to 20 years to assess changes in bone mineral density and the incidence of fractures. The study utilizes urine cadmium as a biomarker to evaluate exposure levels and their potential impact on bone health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who may have been exposed to cadmium through diet or environmental factors.
Not a fit: Patients who are younger than 65 or those without any history of bone health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for osteoporosis and fractures in older adults.
How similar studies have performed: Previous studies have indicated a correlation between cadmium exposure and bone health, but this research aims to provide more definitive evidence through a large prospective approach.
Where this research is happening
Stony Brook, United States
- State University New York Stony Brook — Stony Brook, United States (Active)
Researchers
- Principal investigator: Meliker, Jaymie R — State University New York Stony Brook
- Study coordinator: Meliker, Jaymie R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.