Investigating the link between PFAS exposure and bone health in older adults
Serum PFAS and risk of fracture and bone loss
This study is looking at how certain chemicals called PFAS might affect bone health and increase the risk of fractures in older adults, and it will follow a diverse group of people for up to 20 years to see how these chemicals impact their bones over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Massachusetts Amherst NIH-funded |
| Lab location | 1 site (Hadley, United States) |
| Project ID | NIH-11142526 on NIH RePORTER |
What this research studies
This research examines how exposure to PFAS, a group of environmental chemicals, may affect bone health and increase the risk of fractures in older adults. By analyzing existing data and samples from large osteoporosis studies, the research aims to determine the relationship between serum PFAS levels and bone loss over time. The study will focus on diverse populations to ensure comprehensive findings and will follow participants for up to 20 years to assess long-term effects. This approach will help clarify the potential risks associated with PFAS exposure in aging individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those aged 65 and above, who may be at risk for osteoporosis and fractures.
Not a fit: Patients who are younger than 65 years old or those without any history of bone health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for osteoporosis and fractures in older adults.
How similar studies have performed: Previous research has indicated potential links between environmental toxins and bone health, but this specific investigation into PFAS is novel and aims to fill critical knowledge gaps.
Where this research is happening
Hadley, United States
- University of Massachusetts Amherst — Hadley, United States (Active)
Researchers
- Principal investigator: Reeves, Katherine Whitney — University of Massachusetts Amherst
- Study coordinator: Reeves, Katherine Whitney
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.