Southern California Center for Alcoholic Liver Disease and Cirrhosis (ALPD)
Official title: Southern California Research Center for ALPD and Cirrhosis
Funded at University of Southern California · NIH-11397370 · Data updated 2026-11-12
A national research center based in Southern California aims to advance understanding and treatment of alcoholic liver disease and cirrhosis by coordinating researchers, training students, and fostering collaborations.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | December 31, 1998 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $414,928 |
| NIH project number | 5P50AA011999-28 |
| Project ID | NIH-11397370 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not a direct patient-treatment study; however, it supports research efforts that may ultimately benefit individuals with alcoholic liver disease.
✕Less likely to help
Patients not directly involved in clinical trials or patient-facing activities may not benefit from this core alone.
What this research studies
This grant supports an administrative core that keeps the center organized, communicates updates among researchers, and manages budgets and meetings. It also helps develop new program ideas, promote collaborations, and grow the careers of graduate students, postdocs, and early‑career investigators. By coordinating training, outreach, and scientific meetings, the center builds a stronger network to study alcohol-related liver conditions. The focus is on facilitating high-quality research rather than conducting a single study itself.
Why it matters
Potential benefit: If successful, patients could benefit from faster translation of research findings into improved care for alcoholic liver disease and cirrhosis.
How similar studies have gone: Other centers with strong administrative cores have successfully accelerated collaboration and training, improving research output.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Tsukamoto, Hidekazu — University of Southern California
- Study coordinator: Tsukamoto, Hidekazu
Related research
Other NIH-funded projects on the same topics.
-
Statin therapy for people with compensated cirrhosis
A big, long-term study at a major university is looking at whether statins can help people with compensated cirrhosis live longer and feel better.
-
Liver Cirrhosis Network: Centers for Clinical Research
A multicenter study in people with cirrhosis from different causes (including HIV, NASH, and alcohol-related liver disease) to collect data and samples and test new ways to predict and monitor disease progression.
-
Outcomes in cirrhosis from different causes and the role of HIV and simvastatin
This study looks at how cirrhosis from alcohol, HIV, and other causes affects patients and whether simvastatin can influence outcomes.
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Liver Cirrhosis Network: Mayo Clinic's Clinical Research Center
A Mayo Clinic-led project will follow and help people with compensated cirrhosis, using data, imaging, and a big AI tool to predict when complications may happen and test whether a statin can improve outcomes.
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Understanding how risk factors affect progression of cirrhosis and response to statins in patients with cirrhosis
This project follows people with cirrhosis to see what factors speed up their liver disease and whether statin medicines help prevent worsening.
-
Cirrhosis Network study to understand mortality and therapies
A large, multi-center study in people with cirrhosis to find better ways to predict deaths and test the potential of statins to prevent complications like liver cancer and liver failure.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.