Smoking-cessation meds with a team approach for people with HIV (SMARTTT)
Official title: Smoking cessation Medication And Rewards using a Teamlet to Treat Tobacco use disorder (SMARTTT) among Persons with HIV: A multi-site hybrid type 2 effectiveness-implementation trial
Funded at Yale University · NIH-11169520 · Data updated 2026-11-12
A multi-site study tests a team-based plan using medication and rewards to help people with HIV quit smoking.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 16, 2026 |
| Project end | August 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $1,637,138 |
| NIH project number | 1R01AA032477-01 |
| Project ID | NIH-11169520 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with HIV who currently smoke and are willing to participate in a clinic-based cessation program.
✕Less likely to help
Individuals not interested in cessation medications or unable to participate in clinic-based teams may not benefit.
What this research studies
This project focuses on people living with HIV who smoke and aims to combine smoking-cessation medicines with contingencies that reward progress. It uses a teamlet model, where small teams work with clinicians to improve access to medications and support. The study will compare approaches in real clinic settings to see if the team-based method increases quit rates and adherence, while addressing health disparities. The plan blends patient choice, flexible delivery (in-person or remote), and practical strategies for implementation in HIV care clinics.
Why it matters
Potential benefit: If successful, patients with HIV could quit smoking more easily and improve heart, lung, and overall health.
How similar studies have gone: Previous work suggests team-based, contingency-managed approaches can improve quit rates in HIV care settings, but this study tests broader implementation.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Edelman, E. Jennifer — Yale University
- Study coordinator: Edelman, E. Jennifer
Related research
Other NIH-funded projects on the same topics.
-
Social stress and smoking: why disadvantaged young adults struggle to quit
This grant looks at how daily social stress affects if and when disadvantaged young adults who smoke can quit and stay quit.
-
I-STOP: a mobile health program to help people with HIV quit smoking
A smartphone-based program designed to help people with HIV quit smoking in a sustainable, affordable way.
-
Smoking cessation help for people with HIV in South Africa
A program is being tested to help people living with HIV in South Africa quit smoking in ways that fit low-resource clinics and show good value.
-
Mobile tools to understand how sleep affects quitting smoking
This project uses a smartphone to track sleep and smoking in lower-income adults trying to quit to find how sleep patterns relate to staying smoke-free.
-
Integrated approach to lung screening and quitting for African Americans
A multi-level program aims to boost LDCT lung cancer screening uptake and help African American smokers quit, with support from a comprehensive community-focused plan.
-
Peer-led smoking-cessation program for public housing residents
A peer-led program with eight group sessions plus nicotine replacement therapy is tested on adults living in public housing to help them quit smoking.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.