NIH-funded research U01 cooperative agreement

I-STOP: a mobile health program to help people with HIV quit smoking

Official title: Implementing Sustainable mobile health Technology to Optimize smoking cessation Program for people with HIV (I-STOP)

Funded at University of Oklahoma Hlth Sciences Ctr · NIH-11535367 · Data updated 2026-11-12

A smartphone-based program designed to help people with HIV quit smoking in a sustainable, affordable way.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Oklahoma Hlth Sciences Ctr
NIH-funded
Lab location1 site (Oklahoma City, United States)
Project startAugust 12, 2024
Project endJuly 31, 2029
Funding year2026
Award (this year)$111,521
NIH project number3U01CA294811-03S1
Project IDNIH-11535367 on NIH RePORTER

Who could benefit from this research

Could help

Adults living with HIV who smoke and receive care in diverse US settings, especially underserved or low-resource clinics.

Less likely to help

Patients who do not smoke or prefer not to use mobile health tools may see limited direct benefit.

What this research studies

This project aims to implement a scalable, automated mobile health smoking-cessation program tailored for people with HIV, using interactive and personalized app content. It builds on proven strategies like Ask-Advise-Connect to identify smokers, advise quit attempts, and connect patients to treatment. The goal is to make tobacco-cessation support available in diverse HIV care settings, including rural and underserved communities, and to study how to sustain these practices over time. The study will link patients who smoke to evidence-based cessation resources and track how well the program works in real-world clinics.

Why it matters

Potential benefit: If successful, the program could help more people with HIV quit smoking, improving cancer outcomes and overall health.

How similar studies have gone: Previous US studies showed that AAC-like approaches and mHealth tools can support cessation, and this work extends those findings to new clinical settings.

Where this research is happening

  • University of Oklahoma Hlth Sciences Ctr
    Oklahoma City, United States
    Active

Researchers

  • Principal investigator: Bui, Thanh C. — University of Oklahoma Hlth Sciences Ctr
  • Study coordinator: Bui, Thanh C.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.