Real-world use of quit aids in US adults
Official title: Real World Effectiveness of Naturalistic Use of Pharmacologic Smoking Cessation Aids in US Adults.
Funded at University of Nebraska Medical Center · NIH-11447909 · Data updated 2026-11-12
This project studies how well different quitting aids work in everyday life for adults in the United States who smoke.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project start | August 1, 2026 |
| Project end | July 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $948,630 |
| NIH project number | 1R01CA309463-01A1 |
| Project ID | NIH-11447909 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21 and older who smoke and are willing to be followed over time to report their quitting attempts and aid use.
✕Less likely to help
Individuals who do not smoke or who choose not to participate in follow-up data collection may not benefit.
What this research studies
Researchers will follow a nationally representative group of US adults who smoke to see how well various quitting aids perform outside of clinical trials, using data collected every two weeks. The study will look at medications like bupropion and other products, as well as nonmedicinal options, to understand what helps people quit in real life. Data come from the Understanding America Study, tracking people’s quit attempts, use of aids, and outcomes over time. The goal is to inform policy and practice about which aids actually support lasting cessation in diverse communities.
Why it matters
Potential benefit: If successful, findings could guide public health priorities and improve access to effective quitting aids for more people who smoke.
How similar studies have gone: Previous trials show efficacy of cessation aids under controlled conditions; real-world data on effectiveness across diverse populations are still needed.
Where this research is happening
-
University of Nebraska Medical Center
Omaha, United States Active
Researchers
- Principal investigator: Dai, Hongying Daisy — University of Nebraska Medical Center
- Study coordinator: Dai, Hongying Daisy
Related research
Other NIH-funded projects on the same topics.
-
Helping people with HIV/AIDS in South Africa quit smoking and reduce harm from tobacco use
This study is looking for ways to help people with HIV/AIDS in South Africa quit smoking by using a telehealth program that offers support through texting, comparing e-cigarettes and nicotine replacement options to see which works better for them.
-
Social stress and smoking: why disadvantaged young adults struggle to quit
This grant looks at how daily social stress affects if and when disadvantaged young adults who smoke can quit and stay quit.
-
I-STOP: a mobile health program to help people with HIV quit smoking
A smartphone-based program designed to help people with HIV quit smoking in a sustainable, affordable way.
-
Smoking cessation help for people with HIV in South Africa
A program is being tested to help people living with HIV in South Africa quit smoking in ways that fit low-resource clinics and show good value.
-
Mobile tools to understand how sleep affects quitting smoking
This project uses a smartphone to track sleep and smoking in lower-income adults trying to quit to find how sleep patterns relate to staying smoke-free.
-
Integrated approach to lung screening and quitting for African Americans
A multi-level program aims to boost LDCT lung cancer screening uptake and help African American smokers quit, with support from a comprehensive community-focused plan.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.