Racial and ethnic disparities in kidney disease progression and onset
Official title: Racial and ethnic disparities in kidney outcomes among people at risk for chronic kidney disease (CKD)
Funded at University of Virginia · NIH-11225497 · Data updated 2026-11-12
Aimed at understanding why Black adults with or at risk for chronic kidney disease experience different outcomes and onset ages compared with other groups.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project start | December 5, 2017 |
| Project end | April 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $776,121 |
| NIH project number | 2R01DK112008-05A1 |
| Project ID | NIH-11225497 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21 years and older, especially Black Americans or other at-risk racial/ethnic groups.
✕Less likely to help
Individuals without CKD risk factors or who do not belong to the studied populations may have limited direct benefit.
What this research studies
This project looks at how race and ethnicity influence kidney disease progression from the earliest stages through end-stage disease. It builds on prior findings that Black patients show faster progression to kidney failure but lower mortality after CKD onset, and that they develop CKD at younger ages. Researchers will analyze pre-CKD factors and how they contribute to later disparities, using data from adults 21 and older. The goal is to identify actionable points early in life or disease for reducing gaps in kidney health.
Why it matters
Potential benefit: findings could inform targeted prevention and early intervention strategies to reduce disparities in kidney disease outcomes.
How similar studies have gone: Prior work showed racial differences in CKD progression; this study extends to pre-CKD factors to address unanswered questions.
Where this research is happening
-
University of Virginia
Charlottesville, United States Active
Researchers
- Principal investigator: Yan, Guofen — University of Virginia
- Study coordinator: Yan, Guofen
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.