PFAS exposure and kidney disease risk in teens with type 2 diabetes

Who could benefit from this research

What this research studies

This project follows teens and young adults with type 2 diabetes to understand how exposure to PFAS chemicals may worsen kidney health. It uses existing groups of participants and detailed measurements to link PFAS in the body with kidney injury in the proximal tubules. The team will explore whether reducing reabsorption of PFAS in kidney tubules could lower DKD risk, aiming to identify practical prevention or treatment strategies. The study builds on strong preliminary data and collaborates with diverse youth cohorts to ensure findings are relevant to understudied populations.

Why it matters

Where this research is happening

• University of Southern California
  Los Angeles, United States Active

Researchers

• Principal investigator: Goodrich, Jesse Allen — University of Southern California
• Study coordinator: Goodrich, Jesse Allen

Related research

Other NIH-funded projects on the same topics.

• Understanding how PFAS chemicals affect kidney disease in young people with Type 2 diabetes

  This project looks at how common chemicals called PFAS might contribute to kidney problems in young people with Type 2 diabetes.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11190901

• Investigating the impact of PFAS on kidney disease in young people with type 2 diabetes

  This study is looking at how certain chemicals called PFAS might affect kidney health in young people with type 2 diabetes, helping to find out who might be at risk for kidney problems and how these chemicals could be involved.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11075249

• Investigating how PFAS exposure affects kidney health in youth with type 2 diabetes

  This study is looking at how certain harmful chemicals called PFAS affect kidney health in young people with type 2 diabetes, especially in Latinx and African American youth, to find ways to prevent and treat kidney problems.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-10942017

• Rapid, multi-drug initiation for people with CKD and type 2 diabetes

  A small study will try starting several key diabetes and kidney medicines at the same time in adults with CKD and type 2 diabetes to see if this fast plan is safe and helpful.

  NIH research Baylor Research Institute · Dallas, United States · NIH-11343746

• Improving heart- and kidney-protective treatment for people with type 2 diabetes and chronic kidney disease

  This project will help people with type 2 diabetes and chronic kidney disease get proven medicines that protect the heart and kidneys but are often missed.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11303260

• Improving heart and kidney treatment for patients with diabetes

  This study is looking into why people with type 2 diabetes and chronic kidney disease aren't getting the heart-protecting treatments they need, and it aims to find ways to make sure these important medications are prescribed more often.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11015914

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.