Investigating the impact of PFAS on kidney disease in young people with type 2 diabetes

PFAS and Diabetic Kidney Disease in Young Onset Type 2 Diabetes: Emerging Risk Factors and Underlying Mechanisms

NIH-funded research University of Southern California · NIH-11075249

This study is looking at how certain chemicals called PFAS might affect kidney health in young people with type 2 diabetes, helping to find out who might be at risk for kidney problems and how these chemicals could be involved.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Southern California NIH-funded
Lab location1 site (Los Angeles, UNITED STATES)
Project IDNIH-11075249 on NIH RePORTER

What this research studies

This research focuses on understanding how exposure to PFAS, a group of artificial chemicals, may contribute to diabetic kidney disease (DKD) in young individuals with type 2 diabetes. By analyzing existing health data and biological samples from a long-term study, researchers aim to identify youth at risk for DKD and explore the underlying mechanisms linking PFAS exposure to kidney function impairment. The study will measure levels of various PFAS and their potential effects on kidney health over time.

Who could benefit from this research

Good fit: Ideal candidates for this research are young individuals aged 12 to 20 who have been diagnosed with type 2 diabetes.

Not a fit: Patients who do not have type 2 diabetes or are outside the age range of 12 to 20 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better identification and management of kidney disease in young people with type 2 diabetes, ultimately improving their health outcomes.

How similar studies have performed: While the association between PFAS exposure and kidney disease is emerging, this specific approach to studying its effects in youth with type 2 diabetes is novel and has not been extensively tested.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions adult onset diabetesAdult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.