Investigating the impact of PFAS on kidney disease in young people with type 2 diabetes
Official title: PFAS and Diabetic Kidney Disease in Young Onset Type 2 Diabetes: Emerging Risk Factors and Underlying Mechanisms
Funded at University of Southern California · NIH-11075249 · Data updated 2026-11-12
This study is looking at how certain chemicals called PFAS might affect kidney health in young people with type 2 diabetes, helping to find out who might be at risk for kidney problems and how these chemicals could be involved.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | April 16, 2024 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $162,783 |
| NIH project number | 5K01ES036193-02 |
| Project ID | NIH-11075249 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are young individuals aged 12 to 20 who have been diagnosed with type 2 diabetes.
✕Less likely to help
Patients who do not have type 2 diabetes or are outside the age range of 12 to 20 may not benefit from this research.
What this research studies
This research focuses on understanding how exposure to PFAS, a group of artificial chemicals, may contribute to diabetic kidney disease (DKD) in young individuals with type 2 diabetes. By analyzing existing health data and biological samples from a long-term study, researchers aim to identify youth at risk for DKD and explore the underlying mechanisms linking PFAS exposure to kidney function impairment. The study will measure levels of various PFAS and their potential effects on kidney health over time.
Why it matters
Potential benefit: If successful, this research could lead to better identification and management of kidney disease in young people with type 2 diabetes, ultimately improving their health outcomes.
How similar studies have gone: While the association between PFAS exposure and kidney disease is emerging, this specific approach to studying its effects in youth with type 2 diabetes is novel and has not been extensively tested.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Goodrich, Jesse Allen — University of Southern California
- Study coordinator: Goodrich, Jesse Allen
Related research
Other NIH-funded projects on the same topics.
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PFAS exposure and kidney disease risk in teens with type 2 diabetes
Aging and kidney health study in youths with type 2 diabetes to see how a common chemical (PFAS) affects kidney risk and how to prevent or treat it.
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Understanding how PFAS chemicals affect kidney disease in young people with Type 2 diabetes
This project looks at how common chemicals called PFAS might contribute to kidney problems in young people with Type 2 diabetes.
-
Investigating how PFAS exposure affects kidney health in youth with type 2 diabetes
This study is looking at how certain harmful chemicals called PFAS affect kidney health in young people with type 2 diabetes, especially in Latinx and African American youth, to find ways to prevent and treat kidney problems.
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Rapid, multi-drug initiation for people with CKD and type 2 diabetes
A small study will try starting several key diabetes and kidney medicines at the same time in adults with CKD and type 2 diabetes to see if this fast plan is safe and helpful.
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This project will help people with type 2 diabetes and chronic kidney disease get proven medicines that protect the heart and kidneys but are often missed.
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Why some teens develop type 2 diabetes
This project looks at how puberty, obesity, and social or behavioral factors may cause some adolescents to develop type 2 diabetes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.