Investigating how PFAS exposure affects kidney health in youth with type 2 diabetes
Official title: PFAS Exposure and Diabetic Kidney Disease in Youth with Type 2 Diabetes: A Multi-Omic Approach for Prevention and Treatment
Funded at University of Southern California · NIH-10942017 · Data updated 2026-11-12
This study is looking at how certain harmful chemicals called PFAS affect kidney health in young people with type 2 diabetes, especially in Latinx and African American youth, to find ways to prevent and treat kidney problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | September 10, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $746,198 |
| NIH project number | 1R01DK140831-01 |
| Project ID | NIH-10942017 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are youth aged 12-20 years with type 2 diabetes, particularly those from Latinx or African American backgrounds.
✕Less likely to help
Patients who do not have type 2 diabetes or are outside the age range of 12-20 years may not benefit from this research.
What this research studies
This research focuses on understanding the impact of PFAS, a group of harmful chemicals, on kidney health in young individuals with type 2 diabetes. It aims to identify how these substances contribute to diabetic kidney disease, particularly in Latinx and African American youth who are disproportionately affected. The study will utilize a multi-omic approach, analyzing biological markers and pathways to uncover modifiable risk factors and potential therapeutic strategies. By examining two well-characterized cohorts, the research seeks to provide insights that could lead to better prevention and treatment options for diabetic kidney disease in adolescents.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for diabetic kidney disease in youth, potentially reducing the risk of early dialysis and death.
How similar studies have gone: This research is pioneering in its approach to linking PFAS exposure with diabetic kidney disease in youth, as similar studies have not been extensively conducted in this demographic.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Goodrich, Jesse Allen — University of Southern California
- Study coordinator: Goodrich, Jesse Allen
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.