Investigating how PFAS exposure affects kidney health in youth with type 2 diabetes
PFAS Exposure and Diabetic Kidney Disease in Youth with Type 2 Diabetes: A Multi-Omic Approach for Prevention and Treatment
This study is looking at how certain harmful chemicals called PFAS affect kidney health in young people with type 2 diabetes, especially in Latinx and African American youth, to find ways to prevent and treat kidney problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10942017 on NIH RePORTER |
What this research studies
This research focuses on understanding the impact of PFAS, a group of harmful chemicals, on kidney health in young individuals with type 2 diabetes. It aims to identify how these substances contribute to diabetic kidney disease, particularly in Latinx and African American youth who are disproportionately affected. The study will utilize a multi-omic approach, analyzing biological markers and pathways to uncover modifiable risk factors and potential therapeutic strategies. By examining two well-characterized cohorts, the research seeks to provide insights that could lead to better prevention and treatment options for diabetic kidney disease in adolescents.
Who could benefit from this research
Good fit: Ideal candidates for this research are youth aged 12-20 years with type 2 diabetes, particularly those from Latinx or African American backgrounds.
Not a fit: Patients who do not have type 2 diabetes or are outside the age range of 12-20 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for diabetic kidney disease in youth, potentially reducing the risk of early dialysis and death.
How similar studies have performed: This research is pioneering in its approach to linking PFAS exposure with diabetic kidney disease in youth, as similar studies have not been extensively conducted in this demographic.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Goodrich, Jesse Allen — University of Southern California
- Study coordinator: Goodrich, Jesse Allen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.