Improving HIV prevention and care for adolescents and young adults in Uganda

Implementation Science to Understand and Design Stakeholder Informed Innovative Interventions to Improve Adolescent and Youth HIV Prevention and Care Continuums in Rural and Urban Uganda

NIH-funded research Mu-Jhu Care · NIH-11395132

This project will offer long-acting injectable HIV prevention and youth-centered care approaches to help adolescents and young adults in Uganda start and stay on effective prevention and treatment.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMu-Jhu Care NIH-funded
Lab location1 site (Kampala, Uganda)
Project IDNIH-11395132 on NIH RePORTER

What this research studies

You and other young people (ages 15–24) will be screened using new methods to find who is at high risk for HIV. If you are HIV-negative and at risk, the project may offer long-acting injectable PrEP (cabotegravir) through community delivery to avoid daily pills. If you are living with HIV, you would be offered the SEARCH-Youth support package with life-stage tailored help to start and stay on treatment and reach viral suppression. The program is delivered in both rural and urban communities in Uganda and uses real-world delivery models while collecting health outcomes.

Who could benefit from this research

Good fit: Ideal candidates are adolescents and young adults (approximately 15–24 years old) in the study communities in Uganda who are either high-risk HIV-negative individuals eligible for PrEP or HIV-positive youth needing support to achieve viral suppression.

Not a fit: People outside the 15–24 age range, those not living in participating Ugandan communities, or individuals with medical contraindications to cabotegravir or who refuse injections are unlikely to benefit directly from this project.

Why it matters

Potential benefit: If successful, this work could expand access to effective long-acting PrEP and improve viral suppression among adolescents and young adults, lowering new infections and improving health.

How similar studies have performed: Clinical trials have shown cabotegravir injections prevent HIV effectively, but delivering long-acting PrEP and youth-tailored care in routine community settings is newer and still being refined.

Where this research is happening

Kampala, Uganda

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.