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Innovative HIV Prevention and Care Interventions for Adolescents and Young Adults in Uganda

Official title: Implementation Science to Understand and Design Stakeholder Informed Innovative Interventions to Improve Adolescent and Youth HIV Prevention and Care Continuums in Rural and Urban Uganda

Funded at Mu-Jhu Care · NIH-11399046 · Data updated 2026-11-12

A Ugandan study tests new ways to help teens and young adults (ages 15–24) prevent HIV and stay healthy if they are living with HIV, using community-based options and long-acting PrEP.

More HIV Prevention research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMu-Jhu Care
NIH-funded
Lab location1 site (Kampala, Uganda)
Project startSeptember 8, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$288,988
NIH project number5UG1HD113241-04
Project IDNIH-11399046 on NIH RePORTER

Who could benefit from this research

Could help

Young people aged 15–24 in Uganda at risk for HIV or living with HIV who may benefit from targeted prevention and care interventions.

Less likely to help

Youth outside Uganda or those not at elevated risk or not receiving HIV prevention or care services may not benefit from these interventions.

What this research studies

This project focuses on improving HIV prevention and care for Ugandan youth by testing practical, community-based delivery of a long-acting PrEP option and support interventions. It uses real-world implementation methods to see which strategies help high-risk youth start and stay on prevention and achieve viral suppression. Researchers will screen for HIV risk, apply MOH-approved delivery models, and use a hybrid design to measure both health outcomes and how well the interventions can be put into practice. The study draws on youth-focused clinical trial expertise to tailor interventions to life-stage needs and reduce barriers like pill burden and stigma.

Why it matters

Potential benefit: If successful, the project could increase PrEP uptake, improve adherence, and boost viral suppression among Ugandan youth, reducing HIV transmission and improving health outcomes.

How similar studies have gone: Previous youth-focused HIV prevention and care efforts show promise; this study extends those strategies with long-acting PrEP and implementation science approaches.

Where this research is happening

  • Mu-Jhu Care
    Kampala, Uganda     Active

Researchers

  • Principal investigator: Musoke, Philippa — Mu-Jhu Care
  • Study coordinator: Musoke, Philippa

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
View on NIH RePORTER ↗ Search related trials →
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.