NIH-funded research R01 grant

Brief alcohol help to improve PrEP use in Vietnam

Official title: A brief alcohol intervention to reduce alcohol use and improve PrEP outcomes: A randomized controlled trial.

Funded at Univ of North Carolina Chapel Hill · NIH-11402229 · Data updated 2026-11-12

A short, friendly program helps people starting or restarting PrEP in Vietnam to drink less and stick with PrEP to prevent HIV.

More Alcohol Use research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startSeptember 20, 2022
Project endJuly 31, 2027
Funding year2026
Award (this year)$488,629
NIH project number5R01AA030479-05
Project IDNIH-11402229 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults in Vietnam who are starting or restarting PrEP and report unhealthy alcohol use.

Less likely to help

Patients who do not use PrEP or do not have unhealthy alcohol use may not benefit.

What this research studies

This project tests a brief alcohol intervention based on Motivational Interviewing and Cognitive Behavioral Therapy to see if it helps people on PrEP in Vietnam take their pills more consistently and reduce risky drinking. It is designed as an effectiveness-implementation trial, comparing the brief intervention to usual care and looking at persistence with PrEP, adherence to the regimen, and drinking patterns. The study will also evaluate whether the program could be scaled up in clinics, including cost, feasibility, and acceptability. The work will be conducted at Hanoi Medical University with local participants who are starting or restarting PrEP.

Why it matters

Potential benefit: If successful, the program could help people on PrEP stay adherent and reduce alcohol-related risk, potentially lowering HIV infection risk.

How similar studies have gone: Previous work linked brief interventions to improved adherence in other health contexts; this study tests applicability to PrEP in Vietnam.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Go, Vivian F. — Univ of North Carolina Chapel Hill
  • Study coordinator: Go, Vivian F.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.