Reduce drinking to improve protection from HIV on PrEP
Official title: A brief alcohol intervention to reduce alcohol use and improve PrEP outcomes: A randomized controlled trial.
Funded at Univ of North Carolina Chapel Hill · NIH-11137738 · Data updated 2026-11-12
This project is trying a short counseling program to help people who drink alcohol while on PrEP drink less and stay on their PrEP medication.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | September 20, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $475,406 |
| NIH project number | 5R01AA030479-04 |
| Project ID | NIH-11137738 on NIH RePORTER |
Who could benefit from this research
✓Could help
People in Vietnam who are starting or restarting PrEP and report unhealthy alcohol use are ideal candidates for this project.
✕Less likely to help
People who do not drink alcohol, are not using PrEP, or who require specialized treatment for severe alcohol dependence may not receive benefit from this brief counseling approach.
What this research studies
If you join, you'll be randomly assigned to receive a brief counseling program based on motivational interviewing and cognitive behavioral skills or to get the clinic's usual care. The team will track your PrEP use, how well you stick to daily pills or event-driven dosing, and your drinking over time. The trial is being run at PrEP clinics in Vietnam, including Hanoi Medical University, and enrolls people starting or restarting PrEP who report unhealthy alcohol use. Researchers will also measure cost, feasibility, and whether clinics and patients find the counseling acceptable for wider use.
Why it matters
Potential benefit: If successful, the counseling could help people on PrEP drink less and maintain better protection against HIV.
How similar studies have gone: Brief alcohol interventions have improved adherence and viral suppression for people living with HIV on treatment, but using them specifically to support PrEP users is relatively new.
Where this research is happening
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Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Go, Vivian F. — Univ of North Carolina Chapel Hill
- Study coordinator: Go, Vivian F.
Related research
Other NIH-funded projects on the same topics.
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A brief alcohol support for PrEP users to boost HIV prevention
A short, friendly program helps people starting or restarting PrEP in Vietnam drink less and stick with PrEP to stay protected.
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Brief alcohol help to improve PrEP use in Vietnam
A short, friendly program helps people starting or restarting PrEP in Vietnam to drink less and stick with PrEP to prevent HIV.
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Helping people on PrEP reduce drinking and stay on HIV prevention
A short counseling program using motivational interviewing and CBT aims to help people on PrEP who drink at risky levels cut back and keep taking their HIV prevention medicine.
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Reducing alcohol use to improve HIV prevention outcomes for men who have sex with men in Vietnam
This study is looking at how a short program can help men who have sex with men in Vietnam drink less alcohol and stick to their HIV prevention medication, PrEP, by offering friendly support and guidance.
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A youth-focused, community-based program tests whether trained young peers can help more adolescents get HIV PrEP in Brazil.
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Peer-led PrEP delivery for youth in Brazil: a youth-focused PrEP access trial
This project tests whether trained youth peer workers can deliver PrEP in community settings to increase PrEP uptake among young people in Brazil.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.