A brief alcohol support for PrEP users to boost HIV prevention
Official title: A brief alcohol intervention to reduce alcohol use and improve PrEP outcomes: A randomized controlled trial.
Funded at Univ of North Carolina Chapel Hill · NIH-11574743 · Data updated 2026-11-12
A short, friendly program helps people starting or restarting PrEP in Vietnam drink less and stick with PrEP to stay protected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | September 20, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $43,494 |
| NIH project number | 3R01AA030479-05S1 |
| Project ID | NIH-11574743 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults initiating or re-initiating PrEP who report unhealthy alcohol use in Vietnam and are willing to participate.
✕Less likely to help
People who do not drink alcohol or do not use PrEP may not benefit.
What this research studies
This project tests a brief alcohol intervention, based on Motivational Interviewing and Cognitive Behavioral Therapy, to help people on PrEP in Vietnam reduce unhealthy drinking. It compares the brief intervention to standard care in a randomized trial, looking at whether participants stay on PrEP longer, take their meds more consistently, and use PrEP in a way that matches their risk. It will also examine changes in alcohol use, and how feasible and affordable it would be to scale up in clinics. The trial will take place at Hanoi Medical University and is designed to inform real-world adoption in PrEP programs.
Why it matters
Potential benefit: If successful, the program could help people on PrEP drink less and stay adherent, potentially improving HIV prevention.
How similar studies have gone: Previous alcohol interventions have improved adherence and health outcomes in related HIV care settings, but this exact PrEP-focused approach in Vietnam is being tested.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Go, Vivian F. — Univ of North Carolina Chapel Hill
- Study coordinator: Go, Vivian F.
Related research
Other NIH-funded projects on the same topics.
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Brief alcohol help to improve PrEP use in Vietnam
A short, friendly program helps people starting or restarting PrEP in Vietnam to drink less and stick with PrEP to prevent HIV.
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Helping people on PrEP reduce drinking and stay on HIV prevention
A short counseling program using motivational interviewing and CBT aims to help people on PrEP who drink at risky levels cut back and keep taking their HIV prevention medicine.
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Reduce drinking to improve protection from HIV on PrEP
This project is trying a short counseling program to help people who drink alcohol while on PrEP drink less and stay on their PrEP medication.
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Reducing alcohol use to improve HIV prevention outcomes for men who have sex with men in Vietnam
This study is looking at how a short program can help men who have sex with men in Vietnam drink less alcohol and stick to their HIV prevention medication, PrEP, by offering friendly support and guidance.
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Peer-led PrEP delivery for youth in Brazil: a community-based randomized trial
A youth-focused, community-based program tests whether trained young peers can help more adolescents get HIV PrEP in Brazil.
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Peer-led PrEP delivery for youth in Brazil: a youth-focused PrEP access trial
This project tests whether trained youth peer workers can deliver PrEP in community settings to increase PrEP uptake among young people in Brazil.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.