ALPD and Cirrhosis Research Center Pilot Projects for New Leaders
Official title: Southern California Research Center for ALPD and Cirrhosis
Funded at University of Southern California · NIH-11397372 · Data updated 2026-11-12
A USC center funds pilots led by young and established scientists to push forward understanding and treatment of alcoholic liver disease and cirrhosis.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | December 31, 1998 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $148,501 |
| NIH project number | 5P50AA011999-28 |
| Project ID | NIH-11397372 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with alcoholic liver disease or cirrhosis who may participate in future pilot studies or receive lessons from new research advances.
✕Less likely to help
Patients unrelated to ALPD or cirrhosis or those not participating in pilot projects may not directly benefit.
What this research studies
This grant supports a Pilot Project Core that helps emerging researchers start independent work related to alcoholic liver disease and cirrhosis. It enables senior postdocs and early-career investigators to develop new ideas with access to the center’s resources and collaborations. The program has a track record of launching new investigators who have gone on to major NIH or other funding and publications. It also fosters collaboration between junior researchers and experienced investigators to advance the field.
Why it matters
Potential benefit: If successful, the program could accelerate new therapies and better understanding for ALPD and cirrhosis, potentially benefiting patients with liver disease.
How similar studies have gone: Historically, pilot core programs have produced multiple NIH grants and publications, indicating potential for meaningful impact.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Tsukamoto, Hidekazu — University of Southern California
- Study coordinator: Tsukamoto, Hidekazu
Related research
Other NIH-funded projects on the same topics.
-
Statin therapy for people with compensated cirrhosis
A big, long-term study at a major university is looking at whether statins can help people with compensated cirrhosis live longer and feel better.
-
Liver Cirrhosis Network: Centers for Clinical Research
A multicenter study in people with cirrhosis from different causes (including HIV, NASH, and alcohol-related liver disease) to collect data and samples and test new ways to predict and monitor disease progression.
-
Outcomes in cirrhosis from different causes and the role of HIV and simvastatin
This study looks at how cirrhosis from alcohol, HIV, and other causes affects patients and whether simvastatin can influence outcomes.
-
Liver Cirrhosis Network: Mayo Clinic's Clinical Research Center
A Mayo Clinic-led project will follow and help people with compensated cirrhosis, using data, imaging, and a big AI tool to predict when complications may happen and test whether a statin can improve outcomes.
-
Understanding how risk factors affect progression of cirrhosis and response to statins in patients with cirrhosis
This project follows people with cirrhosis to see what factors speed up their liver disease and whether statin medicines help prevent worsening.
-
Cirrhosis Network study to understand mortality and therapies
A large, multi-center study in people with cirrhosis to find better ways to predict deaths and test the potential of statins to prevent complications like liver cancer and liver failure.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.