Condition

Transcatheter Aortic Valve Replacement (TAVR) clinical trials and research

• 10Clinical trials
• 7Countries

Newest Transcatheter Aortic Valve Replacement (TAVR) clinical trials

All recruiting trials (10)

• CHATEAU Registry: Real-world outcomes after TAVR

  This registry collects real-world data from adults who had TAVR between 2021 and 2025 to see how they do over time and how valve performance holds up.

  Recruiting Eunpyeong St. Mary's Hospital · Seoul · NCT07709858

• CHORDS Cerebral Protection During TAVR

  This study tests whether using the CHORDS Cerebral Protection System during TAVR reduces brain embolic events compared to the Sentinel system in adults with severe aortic stenosis.

  Recruiting at 14 sites Resonova (Shanghai) Medtech Limited · Bengbu, Anhui and 14 other locations · NCT07648693

• How the type of sedation affects recovery after TAVR

  This study will test whether three common sedation approaches (propofol, dexmedetomidine, or midazolam with fentanyl) change how people recover on the first day after transfemoral TAVR.

  Recruiting Phase 4 Endeavor Health · Glenview, Illinois · NCT07556523

• Using 4D Flow MRI to characterize left ventricular failure

  This project will test whether automated 4D Flow MRI analysis can measure left ventricular dysfunction in adults with severe aortic stenosis who are scheduled for TAVR.

  Recruiting at 2 sites IRCCS Policlinico S. Donato · San Donato Milanese and 1 other locations · NCT07455292

• Electrical acupoint stimulation to prevent low blood pressure during TAVR anesthesia

  We test whether high- versus low-frequency electrical stimulation at three acupoints before anesthesia can reduce drops in blood pressure in people aged 60 and older having TAVR.

  Recruiting Air Force Military Medical University, China · Xi'an, Shannxi · NCT07365345

• Tracking progression and consequences of heart valve disease

  This project will follow adults with moderate or worse valve disease to see if clinical tests and imaging can predict when their condition will get worse.

  Recruiting at 15 sites Second Affiliated Hospital, Zhejiang University, School of Medicine · Fuzhou, Fujian and 14 other locations · NCT07267117

• Using photon-counting CT instead of invasive angiography to check coronary arteries before TAVR

  This test will see if a newer photon-counting CT scan (PCD-CT) can safely replace invasive coronary angiography to look for coronary artery disease in adults having TAVR for severe aortic stenosis.

  Recruiting at 2 sites Medical University Innsbruck · Innsbruck and 1 other locations · NCT07107568

• Long-term outcomes with the SAPIEN 3 Ultra RESILIA heart valve in adults

  This study tests how the SAPIEN 3 Ultra RESILIA valve performs over 10 years in adults undergoing transfemoral TAVR for severe aortic valve disease.

  Recruiting Institut für Pharmakologie und Präventive Medizin · Bad Oeynhausen, North Rhine-Westphalia · NCT06953206

• Transfemoral VitaFlow Liberty treatment for pure aortic regurgitation

  This trial will test whether replacing the aortic valve through the leg with the VitaFlow Liberty valve plus usual medical care helps people aged 60 and older with moderate-to-severe or worse isolated aortic regurgitation.

  Recruiting at 4 sites Phase 4 Ruijin Hospital · Shanghai, Shanghai Municipality and 3 other locations · NCT06818084

• Using Ticagrelor or Aspirin for Patients After Aortic Valve Implantation

  This study tests whether Ticagrelor works better than Aspirin to prevent blood clots and complications in adults with severe aortic stenosis after they have a heart valve replacement.

  Recruiting Phase 4 Fundacin Biomedica Galicia Sur · Vigo, Pontevedra · NCT05283356

Related topics

Quick answers

How many Transcatheter Aortic Valve Replacement (TAVR) clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in China (4 trials), Spain (1 trial), Italy (1 trial), United States (1 trial), Austria (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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