Electrical acupoint stimulation to prevent low blood pressure during TAVR anesthesia
Official title: The Influence of Electrical Acupoint Stimulation at Different Frequencies on Hemodynamics During Anesthesia Induction in Patients Undergoing TAVR Surgery
Run by Air Force Military Medical University, China · NCT07365345 · Data updated 2026-11-12
We test whether high- versus low-frequency electrical stimulation at three acupoints before anesthesia can reduce drops in blood pressure in people aged 60 and older having TAVR.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 60 Years and up |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Air Force Military Medical University, China Academic / other |
| Locations | 1 site (Xi'an, Shannxi) |
| Status | Recruiting |
| Started | January 30, 2026 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | March 25, 2026 |
| Trial ID | NCT07365345 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients aged 60 or older who are scheduled for TAVR under general anesthesia with a BMI between 18 and 30 and without severe liver/kidney dysfunction, decompensated heart failure, active skin infection at stimulation sites, or implanted electrical devices.
✕Probably not a fit
Patients with hemodynamic instability, severe organ dysfunction, BMI outside 18–30, local skin damage or infection, or implanted electrophysiological devices are unlikely to benefit or will be excluded.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Patients scheduled for TAVR under general anesthesia receive electrical stimulation at the acupoints Neiguan, Jianshi, and Baihui within 30 minutes before induction. Participants are assigned to receive either high-frequency or low-frequency stimulation and blood pressure changes during the anesthesia induction period are recorded. The primary comparison is the magnitude and incidence of hypotension and the need for vasoactive drugs during induction. Safety exclusions include implanted electrical devices, severe organ dysfunction, extreme BMI, active skin infection at stimulation sites, or preexisting hemodynamic instability.
Why it matters
Potential benefit: If successful, this approach could reduce anesthesia-induced drops in blood pressure during TAVR and lower the need for vasopressors, improving safety at induction.
How similar studies have gone: Prior small perioperative acupuncture studies have suggested acupoint stimulation can reduce anesthesia-related hypotension, but frequency-specific comparisons are limited and this protocol is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * The age of the patients is 60 years or older; * Patients who are scheduled to undergo TAVR surgery under general anesthesia; Exclusion Criteria: * Body mass index less than 18 kg/m2 or greater than 30 kg/m2; * Hemodynamic instability (severe arrhythmia, decompensated heart failure); * Hypotension after admission requiring intervention with vasoactive drugs; * Severe liver or kidney dysfunction; * Those who are contraindicated for electrical stimulation, including those with local skin damage, infection, or having implanted electrophysiological devices in the body.
Where it's running
-
Xijing Hospital, Fourth Military Medical University
Xi'an, Shannxi, China Recruiting
Study contacts
- Study coordinator: Zhihong Lu
- Email: deerlu23@163.com
- Phone: 86-13891975018
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.