Condition

Aortic Regurgitation clinical trials and research

• 8Clinical trials
• 2Countries

Newest Aortic Regurgitation clinical trials

All recruiting trials (8)

• J-VALVE versus surgical aortic valve replacement for severe aortic regurgitation

  This study will test whether the J‑VALVE transfemoral valve works as well and is as safe as surgical aortic valve replacement in people aged 65 and older with severe native aortic regurgitation.

  Recruiting at 2 sites Second Affiliated Hospital, Zhejiang University, School of Medicine · Hefei, Anhui and 27 other locations · NCT07453407

• DELINEATE-Prospective: AI-assisted echocardiogram analysis for valve disease

  This project will test whether an AI system can automatically analyze echocardiograms to help doctors detect valve problems in adults who get heart ultrasounds.

  Recruiting Columbia University · New York, New York · NCT07197736

• Surgical implantation of a polymer prosthetic mitral or aortic valve

  This will test a surgically implanted polymer heart valve to see if it is safe and works well for adults who need mitral or aortic valve replacement.

  Recruiting Mitrassist Lifesciences Limited Co., Ltd. · Shanghai, Shanghai Municipality · NCT07097740

• Transfemoral VitaFlow Liberty treatment for pure aortic regurgitation

  This trial will test whether replacing the aortic valve through the leg with the VitaFlow Liberty valve plus usual medical care helps people aged 60 and older with moderate-to-severe or worse isolated aortic regurgitation.

  Recruiting at 4 sites Phase 4 Ruijin Hospital · Shanghai, Shanghai Municipality and 3 other locations · NCT06818084

• Identifying sex-specific biological markers in valvular heart disease

  This study is testing if special heart scans can help find different biological markers for men and women with aortic valve disease to improve treatment and recovery after surgery.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT06780241

• Surgery versus Trilogy transcatheter valve for treating aortic regurgitation

  This trial tests whether the Trilogy transcatheter heart valve works as well as surgical aortic valve replacement for people with significant native aortic regurgitation.

  Recruiting at 40 sites JenaValve Technology, Inc. · Burlingame, California and 39 other locations · NCT06608823

• Evaluating a new heart valve system for severe aortic regurgitation

  This study is testing a new heart valve system to see if it can safely help people with severe aortic regurgitation who can't have traditional surgery.

  Recruiting at 19 sites Peijia Medical Technology (Suzhou) Co., Ltd. · Beijing, Beijing Municipality and 18 other locations · NCT06101888

• Comparing imaging methods for heart valve disease assessment

  This study is testing whether a new 3D heart imaging method is better than the traditional 2D method for checking how serious heart valve problems are in people with conditions like aortic stenosis and mitral valve regurgitation.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT04126018

Related topics

Quick answers

How many Aortic Regurgitation clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (4 trials), China (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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