Condition

Stage III Pancreatic Cancer AJCC v8 clinical trials and research

• 13Clinical trials
• 2Countries

Newest Stage III Pancreatic Cancer AJCC v8 clinical trials

All recruiting trials (13)

• A tailored web program to boost exercise and healthy eating for pancreatic cancer patients before surgery

  This trial tests a personalized web portal called COMPASS to help adults with stage I–III pancreatic cancer who are receiving neoadjuvant chemotherapy to improve exercise and dietary habits.

  Recruiting OHSU Knight Cancer Institute · Portland, Oregon · NCT07651358

• Combo therapy with selumetinib and trastuzumab deruxtecan for advanced pancreatic cancer

  This phase 1/2 trial tests whether the combination of selumetinib and DS-8201a (trastuzumab deruxtecan) is safe and whether it can help people with unresectable or metastatic pancreatic ductal adenocarcinoma.

  Recruiting Phase 1/2 National Cancer Institute (NCI) · Pittsburgh, Pennsylvania · NCT07619521

• AB801 with chemotherapy and immunotherapy for cholangiocarcinoma and pancreatic cancer

  This phase 1 study tests whether AB801 can be given safely with chemotherapy and immunotherapy in adults with border-line resectable, locally advanced, or metastatic cholangiocarcinoma or pancreatic cancer.

  Recruiting Phase 1 Jonsson Comprehensive Cancer Center · Los Angeles, California · NCT07619313

• TR-002 (Nadofaragene Firadenovec) given by IV for adults with advanced unresectable or metastatic solid tumors and refractory metastatic pancreatic adenocarcinoma

  This Phase 1 trial tests whether weekly intravenous TR-002 is safe and what dose is best for adults with advanced unresectable or metastatic solid tumors or refractory metastatic pancreatic cancer.

  Recruiting Phase 1 University of California, Davis · Sacramento, California · NCT07189195

• OMO-103 for advanced or metastatic pancreatic ductal adenocarcinoma

  This trial tests an experimental IV drug called OMO-103 to see if it changes tumor cells in adults with locally advanced or metastatic pancreatic ductal adenocarcinoma.

  Recruiting Early Phase 1 OHSU Knight Cancer Institute · Portland, Oregon · NCT07089940

• Adding panitumumab to chemotherapy for unresectable or metastatic KRAS wild-type pancreatic cancer

  This trial will test whether giving the antibody panitumumab along with standard chemotherapy helps people with unresectable, locally advanced, or metastatic KRAS wild-type pancreatic cancer live longer.

  Recruiting at 272 sites Phase 3 SWOG Cancer Research Network · Anchorage, Alaska and 273 other locations · NCT06998940

• Higher-dose targeted radiation for locally advanced pancreatic cancer

  This tests whether giving a higher, precisely targeted dose of radiation after initial chemotherapy helps people with locally advanced unresectable pancreatic cancer live longer.

  Recruiting at 327 sites Phase 3 NRG Oncology · Gilbert, Arizona and 332 other locations · NCT06958328

• Using pemigatinib to treat advanced pancreatic cancer with FGFR genetic changes

  This study is testing if a new drug called pemigatinib can help adults with advanced pancreatic cancer that has specific genetic changes feel better and possibly live longer.

  Recruiting at 109 sites Phase 2 Ohio State University Comprehensive Cancer Center · Birmingham, Alabama and 108 other locations · NCT06906562

• Neoadjuvant chemotherapy for resectable pancreatic cancer

  This study is testing a combination of three chemotherapy drugs to see if it helps people with resectable pancreatic cancer get better before surgery.

  Recruiting Phase 2 Georgetown University · Washington D.C., District of Columbia and 1 other locations · NCT06423326

• CPI-613 combined with hydroxychloroquine and chemotherapy for advanced solid tumors

  This study is testing a new combination of treatments, including CPI-613 and hydroxychloroquine, to see if it can help people with advanced solid tumors that haven't improved with other chemotherapy.

  Recruiting Phase 2 Northwestern University · Chicago, Illinois · NCT05733000

• Testing a combination of two anti-cancer drugs for HER2-positive solid tumors

  This study is testing a combination of two cancer drugs to see if they can safely help people with advanced HER2-positive solid tumors.

  Recruiting at 15 sites Phase 1 National Cancer Institute (NCI) · Duarte, California and 17 other locations · NCT05372614

• Testing a new drug combination for advanced cancer and lymphoma

  This study is testing a new combination of two drugs to see if it can help people with advanced cancer and lymphoma feel better and live longer.

  Recruiting at 3 sites Phase 1/2 National Cancer Institute (NCI) · New Haven, Connecticut and 2 other locations · NCT05053971

• Targeted therapy for pancreatic cancer using new drugs

  This study is testing new targeted therapies for pancreatic cancer to see how well they work and if they are safe for patients at different stages of the disease.

  Recruiting Early Phase 1 OHSU Knight Cancer Institute · Portland, Oregon · NCT04005690

Related topics

Quick answers

How many Stage III Pancreatic Cancer AJCC v8 clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (13 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Phase 2: 3, Early Phase 1: 2, Phase 1/2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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