Condition

Locally Advanced Pancreatic Ductal Adenocarcinoma clinical trials and research

• 9Clinical trials
• 4Countries

Newest Locally Advanced Pancreatic Ductal Adenocarcinoma clinical trials

All recruiting trials (9)

• Samuraciclib given before surgery or chemotherapy for certain pancreatic cancers

  This study tests whether taking samuraciclib before standard treatment is safe and helps patients with localized pancreatic cancer.

  Recruiting Phase 1 University of Washington · Seattle, Washington · NCT07645651

• PULSAR personalized ultrafractionated adaptive proton radiotherapy combined with systemic therapy for pancreatic cancer

  This trial will test whether personalized PULSAR proton radiotherapy given after initial chemotherapy can improve local control for people with borderline resectable, locally advanced, or limited metastatic pancreatic cancer.

  Recruiting Phase 2 Samsung Medical Center · Seoul, Select Province/State · NCT07269626

• XER-001 (nasoduodenal amifostine) with SBRT for locally advanced pancreatic cancer

  This trial tests whether giving XER-001 through a nasoduodenal tube together with stereotactic body radiotherapy (SBRT) is safe and helpful for people with locally advanced pancreatic cancer.

  Recruiting at 5 sites Phase 1/2 Xerient Pharma · Duarte, California and 4 other locations · NCT07157033

• GnP plus serplulimab with stereotactic body radiation therapy for first-line locally advanced pancreatic cancer.

  This trial will test whether combining GnP chemotherapy, the immunotherapy serplulimab, and focused SBRT helps people aged 18–75 with untreated, locally advanced pancreatic ductal adenocarcinoma.

  Recruiting Phase 2 West China Hospital · Chengdu, Sichuan · NCT07101679

• OMO-103 for advanced or metastatic pancreatic ductal adenocarcinoma

  This trial tests an experimental IV drug called OMO-103 to see if it changes tumor cells in adults with locally advanced or metastatic pancreatic ductal adenocarcinoma.

  Recruiting Early Phase 1 OHSU Knight Cancer Institute · Portland, Oregon · NCT07089940

• Using advanced MRI to assess treatment response in pancreatic cancer

  This study is testing a new MRI technique to see if it can better predict how well treatment works for people with pancreatic cancer.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06600906

• Tumor DNA and protein testing to understand pancreatic cancer treatment response

  This trial will test whether measuring tumor DNA and proteins from people with resectable or locally advanced pancreatic ductal adenocarcinoma can be done quickly enough and provide information about how their cancer responds to standard chemotherapy.

  Recruiting British Columbia Cancer Agency · Vancouver, British Columbia · NCT06574620

• Combining zimberelimab and quemliclustat with chemotherapy for advanced pancreatic cancer

  This study is testing if a new combination of zimberelimab and quemliclustat with chemotherapy can help people with advanced pancreatic cancer live longer and have better treatment outcomes.

  Recruiting Phase 1/2 Jonsson Comprehensive Cancer Center · Los Angeles, California · NCT05688215

• Targeted therapy for pancreatic cancer using new drugs

  This study is testing new targeted therapies for pancreatic cancer to see how well they work and if they are safe for patients at different stages of the disease.

  Recruiting Early Phase 1 OHSU Knight Cancer Institute · Portland, Oregon · NCT04005690

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Quick answers

How many Locally Advanced Pancreatic Ductal Adenocarcinoma clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (6 trials), Canada (1 trial), South Korea (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 2, Phase 1/2: 2, Phase 2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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