Condition

Soft Tissue Sarcoma (STS) clinical trials and research

• 18Clinical trials
• 13Countries

Newest Soft Tissue Sarcoma (STS) clinical trials

All recruiting trials (18)

• Strasbourg pST soft tissue sarcoma care patterns and survival

  This study looks back at how closely soft tissue sarcoma care in Strasbourg followed international guidelines and whether that related to overall survival, comparing patient care from 2010-2016 to 2017-2024.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07864870

• Lifileucel (Tumor-infiltrating lymphocytes) for advanced soft tissue sarcoma

  This study tests lifileucel, a cell therapy made from a patient’s own tumor cells, in adults with unresectable or metastatic soft tissue sarcoma who have had prior treatments to see if it helps shrink tumors and improve outcomes.

  Recruiting at 2 sites Phase 2 Iovance Biotherapeutics, Inc. · Tampa, Florida and 1 other locations · NCT07741877

• AYA Sarcoma Survivors: Personalized Exercise Program Pilot

  This pilot tests a personalized 12-week exercise program for adolescents and young adults with sarcoma to see if a triage tool can connect them with the right rehabilitation and exercise services.

  Recruiting at 3 sites Dana-Farber Cancer Institute · Boston, Massachusetts and 2 other locations · NCT07662239

• Neoantigen Vaccine SarVac With Tumor-Specific Lymphocytes Plus PD-1 Blocker for Advanced Sarcoma

  This trial tests a personalized cancer vaccine called SarVac, given with a PD-1 blocker, and possibly tumor-specific lymphocytes, to see if it is safe and can help people with advanced soft tissue or bone sarcoma.

  Recruiting Phase 1 Sun Yat-sen University · Guangzhou, Guangdong · NCT07648069

• First-in-human imaging study of 68Ga-DFC413 and comparison with 68Ga-NNS309 in solid tumors

  This study tests a new radioactive imaging agent, 68Ga-DFC413, to see how it behaves in patients with several solid tumors and compares it to 68Ga-NNS309.

  Recruiting at 2 sites Phase 1 Novartis · Odense C and 1 other locations · NCT07630961

• Cryoablation plus anti-PD-1 therapy for advanced soft tissue sarcoma

  This study tests whether freezing tumors and giving camrelizumab can help people with advanced soft tissue sarcoma after standard treatments have failed.

  Recruiting Phase 2 Sun Yat-sen University · Guangzhou, Guangdong · NCT07602049

• Bexmarilimab with doxorubicin for metastatic soft-tissue sarcoma

  This study tests whether adding bexmarilimab to doxorubicin is safe and helps people with metastatic soft-tissue sarcoma.

  Recruiting at 5 sites Phase 1/2 MedSIR · Badalona and 10 other locations · NCT07460986

• Personalised neoadjuvant therapy planning for adults with high‑risk soft tissue sarcoma

  This project tests whether analyzing tumor tissue and clinical data can help guide neoadjuvant chemotherapy decisions for adults with high‑risk soft tissue sarcomas.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT07432932

• Dose‑escalated, short‑course proton radiation for inoperable soft tissue sarcoma

  This will try higher-dose, shorter-course proton radiation to see if it controls tumors better in adults with inoperable soft tissue sarcoma.

  Recruiting Phase 2 Oslo University Hospital · Bergen and 1 other locations · NCT07173972

• Cirtuvivint for selected advanced soft‑tissue sarcomas

  This trial will test whether the oral drug cirtuvivint can help control tumors in people aged 16–70 with certain advanced soft‑tissue sarcomas after prior treatment.

  Recruiting Phase 2 Asociación Europea y Latinoamericana SELNET para la Investigación en Sarcomas · Madrid, Madrid · NCT07032285

• Comparing two types of radiation therapy for soft tissue sarcoma

  This study is testing whether a new type of radiation therapy can work better than the standard treatment for people with soft tissue sarcoma that has a tumor size of at least 5 cm.

  Recruiting Shandong Cancer Hospital and Institute · Jinan, Shandong · NCT06980259

• Detecting double-positive (tumor marker/CD45+) cells in the blood of people with metastatic cancer

  This one-day study will test two blood-based methods to find double-positive tumor/CD45+ circulating cells in adults who are about to start treatment for various metastatic cancers.

  Recruiting Institut Claudius Regaud · Toulouse · NCT06967961

• Comparing wound management techniques after sarcoma surgery

  This study is testing two different ways to close surgical wounds after sarcoma surgery in the groin and thigh to see which method leads to fewer complications like infections and fluid buildup.

  Recruiting Universitätsklinikum Hamburg-Eppendorf · Hamburg, Free and Hanseatic City of Hamburg · NCT06889532

• NK cell therapy using umbilical cord blood for high-risk pediatric soft tissue sarcoma

  This study is testing if a new treatment using natural killer cells from umbilical cord blood can help children with high-risk soft tissue sarcoma feel better and improve their chances of recovery.

  Recruiting at 2 sites Sun Yat-sen University · Guangzhou, Guangdong and 1 other locations · NCT06848582

• Lung wash and tumor fluid markers for sarcoma lung metastases

  This study will test whether lung wash (bronchoalveolar lavage) and tumor fluid biomarkers can indicate how much metastatic soft tissue sarcoma is in the lungs for adults having lung surgery.

  Recruiting Phase 2 University Health Network, Toronto · Toronto, Ontario · NCT06815666

• Using MRI to predict tumor infiltration in soft tissue and bone cancers

  This study is testing if special MRI scans can help doctors better identify tumor spread in patients suspected of having soft tissue sarcoma or bone cancer.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna · NCT06774729

• Imaging study using two antibody fragments in patients with solid tumors

  This study is testing two special antibody fragments in people with solid tumors to see how well they target cancer cells and how they move through the body.

  Recruiting Early Phase 1 Var2 Pharmaceuticals · Groningen, Provincie Groningen · NCT06645808

• Evaluating GI-102 for advanced solid tumors with or without other cancer drugs

  This study is testing a new cancer treatment called GI-102, both on its own and with other cancer drugs, to see how safe it is and how well it works for people with advanced solid tumors.

  Recruiting at 11 sites Phase 1/2 GI Innovation, Inc. · Scottsdale, Arizona and 10 other locations · NCT05824975

Related topics

Quick answers

How many Soft Tissue Sarcoma (STS) clinical trials are recruiting right now?

18, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in China (4 trials), United States (3 trials), Spain (2 trials), France (2 trials), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 5, Phase 1/2: 2, Phase 1: 2, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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