Condition

Soft Tissue Sarcoma Adult clinical trials and research

• 9Clinical trials
• 7Countries

Newest Soft Tissue Sarcoma Adult clinical trials

All recruiting trials (9)

• Moderately Hypofractionated Neoadjuvant Radiotherapy for Soft Tissue Sarcoma of the Limbs or Trunk Wall

  This trial tests whether giving a shorter course of radiotherapy before surgery helps control soft tissue sarcoma in the limbs or trunk without waiting longer.

  Recruiting Phase 2 Centre Oscar Lambret · Lille · NCT07507773

• Personalised neoadjuvant therapy planning for adults with high‑risk soft tissue sarcoma

  This project tests whether analyzing tumor tissue and clinical data can help guide neoadjuvant chemotherapy decisions for adults with high‑risk soft tissue sarcomas.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT07432932

• Dose‑escalated, short‑course proton radiation for inoperable soft tissue sarcoma

  This will try higher-dose, shorter-course proton radiation to see if it controls tumors better in adults with inoperable soft tissue sarcoma.

  Recruiting Phase 2 Oslo University Hospital · Bergen and 1 other locations · NCT07173972

• Three-week preoperative proton versus X-ray radiotherapy for localized soft tissue sarcoma

  This trial tests whether selecting proton rather than standard X‑ray radiotherapy before surgery for adults with localized soft tissue sarcoma can lower long-term radiation side effects without increasing surgical complications.

  Recruiting Phase 2 Oslo University Hospital · Bergen and 3 other locations · NCT07169344

• Tiny, direct injections of PBA-0111 into solid tumors to see local immune and tumor responses

  This study will try tiny, localized injections of PBA-0111 into tumors of adults with head and neck cancer, selected soft-tissue sarcomas, or triple-negative breast cancer to see if it triggers immune activity and tumor cell killing in the tumor microenvironment.

  Recruiting Early Phase 1 Pure Biologics S.A. · Shreveport, Louisiana · NCT06700070

• Combining propranolol and pembrolizumab for advanced soft tissue sarcoma

  This study is testing a new combination of two medications, propranolol and pembrolizumab, to see if it can help people with advanced angiosarcoma or undifferentiated pleomorphic sarcoma live longer and feel better.

  Recruiting at 2 sites Phase 2 Herlev and Gentofte Hospital · Aarhus and 3 other locations · NCT05961761

• Combining pembrolizumab and cabozantinib for advanced sarcomas

  This study is testing if combining two treatments, pembrolizumab and cabozantinib, can help people with advanced types of sarcoma feel better and improve their condition.

  Recruiting at 6 sites Phase 2 Institut Bergonié · Bordeaux and 9 other locations · NCT05182164

• Combining Retifanlimab with chemotherapy for advanced soft tissue sarcoma

  This study is testing if adding Retifanlimab to chemotherapy can help people with advanced soft tissue sarcoma fight their cancer better than the usual treatments.

  Recruiting Phase 1/2 Memorial Sloan Kettering Cancer Center · New York, New York · NCT04577014

• Combined treatment for soft tissue sarcoma using radiation therapy and surgery

  This study is testing a new three-step treatment for people with soft tissue sarcoma that combines radiation therapy before and after surgery to see if it helps improve their outcomes.

  Recruiting N.N. Petrov National Medical Research Center of Oncology · Saint Petersburg · NCT04330456

Related topics

Quick answers

How many Soft Tissue Sarcoma Adult clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in Norway (3 trials), United States (2 trials), France (2 trials), Russia (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 5, Phase 1/2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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