Condition

Secondary Central Nervous System Lymphoma clinical trials and research

• 7Clinical trials
• 1Country

Newest Secondary Central Nervous System Lymphoma clinical trials

All recruiting trials (7)

• MB-CART19.1 cellular therapy for people with central nervous system lymphoma

  This will test whether MB-CART19.1 cellular therapy is safe and helps adults with relapsed or refractory primary or secondary central nervous system lymphoma.

  Recruiting at 7 sites Phase 1 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT07137494

• Epcoritamab plus ibrutinib for central nervous system lymphoma

  This trial tests whether combining epcoritamab and ibrutinib is safe and tolerable for adults with relapsed or refractory primary or secondary central nervous system lymphoma.

  Recruiting at 8 sites Phase 1 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 7 other locations · NCT07082868

• Glofitamab after obinutuzumab pre-treatment for central nervous system lymphoma

  This trial will test if giving glofitamab after a short obinutuzumab pre-treatment is safe and helpful for adults with primary or secondary central nervous system lymphoma.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06922604

• Combining zanubrutinib and pemetrexed for treating relapsed or refractory CNS lymphomas

  This study is testing if combining two medications, zanubrutinib and pemetrexed, can help people with relapsed or stubborn central nervous system lymphomas feel better and live longer.

  Recruiting Phase 2 Baptist Health South Florida · Miami, Florida · NCT05681195

• Combination treatment of Tafasitamab and Lenalidomide for relapsed CNS lymphoma

  This study is testing a combination of two drugs, Tafasitamab and Lenalidomide, to see if they can help people with relapsed central nervous system lymphoma feel better and improve their treatment outcomes.

  Recruiting Phase 1/2 University of California, San Francisco · San Francisco, California · NCT05351593

• Using acalabrutinib to prevent relapse in patients with large B-cell lymphoma

  This study is testing if the drug acalabrutinib can help prevent cancer from coming back in patients with large B-cell lymphoma who are at high risk after treatment.

  Recruiting at 2 sites Phase 1/2 Jonsson Comprehensive Cancer Center · Los Angeles, California and 2 other locations · NCT05256641

• Assessing cognitive effects of whole brain radiation therapy in blood cancer patients

  This study is testing how whole brain radiation therapy affects thinking and memory in blood cancer patients, while also looking at quality of life and brain changes over time.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT05011045

Related topics

Quick answers

How many Secondary Central Nervous System Lymphoma clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Phase 1/2: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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