Condition
CNS Lymphoma clinical trials and research
As of November 12, 2026, Find a Trial lists 7 CNS Lymphoma clinical trials that are recruiting, at sites in 4 countries (most in United States (4), China (1), United Kingdom (1)). By phase: Phase 1/2 (3), Phase 1 (2), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 7Clinical trials
- 4Countries
Newest CNS Lymphoma clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Treatment of relapsed CNS large B-cell lymphoma with Relma-cel and Tislelizumab | Phase 2 | Beijing and 5 other locations | Recruiting | Mar 14, 2025 |
| Zanubrutinib combined with chemotherapy for patients with secondary CNS lymphoma | Phase 1 | Miami, Florida | Recruiting | Dec 12, 2024 |
| T-Cell Therapy for Adults with Relapsed B-Cell Non-Hodgkin's Lymphoma | Phase 1/2 | Sacramento, California and 4 other locations | Recruiting | Apr 2, 2024 |
| Treatment of CNS lymphoma using targeted endoradiotherapy | Phase 1/2 | Munich, Bavaria and 1 other locations | Recruiting | Nov 15, 2023 |
| CLIMB: using scans and tissue biomarkers to learn more about primary CNS lymphoma | — | Sutton | Recruiting | Apr 25, 2023 |
| Combination treatment of Tafasitamab and Lenalidomide for relapsed CNS lymphoma | Phase 1/2 | San Francisco, California | Recruiting | Apr 28, 2022 |
| Testing a new CAR T cell therapy for adolescents and adults with relapsed B-cell Non-Hodgkin Lymphoma | Phase 1 | Aurora, Colorado | Recruiting | Oct 28, 2021 |
All recruiting trials (7)
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Treatment of relapsed CNS large B-cell lymphoma with Relma-cel and Tislelizumab
This study is testing a new treatment combining a cellular therapy and an immunotherapy for people with relapsed central nervous system large B-cell lymphoma to see if it helps them feel better and live longer.
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Zanubrutinib combined with chemotherapy for patients with secondary CNS lymphoma
This study is testing if a new combination of medications, including Zanubrutinib and chemotherapy, can help people with secondary Central Nervous System lymphoma feel better and improve their health.
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T-Cell Therapy for Adults with Relapsed B-Cell Non-Hodgkin's Lymphoma
This study is testing a new T-cell therapy to see if it can help adults with relapsed B-cell non-Hodgkin's lymphoma feel better.
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Treatment of CNS lymphoma using targeted endoradiotherapy
This study is testing a new treatment for patients with recurrent or hard-to-treat central nervous system lymphoma to see if it is safe and effective.
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CLIMB: using scans and tissue biomarkers to learn more about primary CNS lymphoma
This project will try to use brain scans and tumour tissue from adults with newly diagnosed primary CNS lymphoma to find markers that predict treatment response and time without disease progression.
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Combination treatment of Tafasitamab and Lenalidomide for relapsed CNS lymphoma
This study is testing a combination of two drugs, Tafasitamab and Lenalidomide, to see if they can help people with relapsed central nervous system lymphoma feel better and improve their treatment outcomes.
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Testing a new CAR T cell therapy for adolescents and adults with relapsed B-cell Non-Hodgkin Lymphoma
This study is testing a new CAR T cell therapy to see if it can help adolescents and adults with relapsed B-cell Non-Hodgkin Lymphoma feel better and improve their chances of recovery.
Related topics
Quick answers
How many CNS Lymphoma clinical trials are recruiting right now?
7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in United States (4 trials), China (1 trial), United Kingdom (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1/2: 3, Phase 1: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.