Condition

Sciatica clinical trials and research

• 11Clinical trials
• 7Countries

Newest Sciatica clinical trials

All recruiting trials (11)

• Steroid Injections for Back and Neck Pain: What Works Best

  This study tests different steroid injections and combinations to see what provides the best pain relief and function for adults with back or neck pain.

  Recruiting Phase 4 Wilderman Medical Clinic · Thornhill, Ontario · NCT07762170

• Somatosensory motor training with or without Kinesio tape for sciatica

  This trial tests whether adding Kinesio tape to somatosensory motor control training helps people with discogenic sciatica reduce pain and improve movement and balance.

  Recruiting Riphah International University · Sialkot · NCT07756905

• Three CT Signs of Nerve-Root Suffering in Low-Back Sciatica: How Often They Occur in Patients Referred for CT-Guided Nerve-Root Infiltration

  This study tests whether three specific CT signs align with the nerve root causing symptoms in adults with low-back sciatica who are scheduled for CT-guided nerve-root infiltration.

  Recruiting Centre Hospitalier Universitaire de Nice · Nice, Alpes Maritimes · NCT07690449

• Comparing tensioner vs slider neurodynamic techniques for sciatic nerve pain

  This trial tests whether tensioner or slider neurodynamic therapy is better at reducing pain and improving function for people with sciatica.

  Recruiting Ibadat International University, Islamabad · Rawalpindi, Punjab Province · NCT07632612

• Finnish comparison of microdiscectomy versus sham surgery for lumbar disc herniation

  This trial tests whether microdiscectomy provides better pain relief and recovery than a sham operation for adults with sciatica from a lumbar disc herniation who haven't improved after at least six weeks of non-surgical care.

  Recruiting Helsinki University Central Hospital · Helsinki · NCT07418944

• Single-session electrical nerve stimulation for sciatic-related leg pain

  A one-time Percutaneous Electrical Nerve Stimulation (PENS) treatment near the sciatic nerve is tested to see if it helps long-standing leg pain from low back issues.

  Recruiting Universidad Complutense de Madrid · Madrid, Madrid · NCT07377357

• PENS near the sciatic nerve plus therapeutic exercise for leg pain from sciatica

  This study tests whether a nearby nerve stimulation procedure combined with a structured exercise program can help people with long-lasting sciatica pain.

  Recruiting Universidad Complutense de Madrid · Madrid, Madrid · NCT07373808

• Safety of a single transforaminal C-1101 injection versus saline for chronic sciatica

  This will test whether a single transforaminal epidural injection of C-1101 is safe and well tolerated compared with sterile saline in adults with chronic sciatica who have not improved with conservative care.

  Recruiting at 5 sites Phase 1 Consano Bio · Fernandina Beach, Florida and 5 other locations · NCT07264270

• Move-MORE: Online mindfulness, gentle movement, and motivational coaching for lumbosacral radiculopathy

  This project tests whether an online program of mindfulness, gentle movement, and motivational interviewing can help adults with chronic lumbosacral radiculopathy (sciatica) reduce pain, improve function, and increase daily activity.

  Recruiting National University of Natural Medicine · Portland, Oregon · NCT07125027

• Effects of sensorimotor training with and without myofascial release for sciatica

  This study is testing whether adding myofascial release to sensorimotor training can help people with sciatica feel less pain and move better.

  Recruiting Riphah International University · Lahore, Punjab Province · NCT06696898

• Investigating how cannabis helps relieve pain

  This study is testing how vaporized cannabis helps relieve pain by looking at how it affects the brain while participants feel controlled heat.

  Recruiting Early Phase 1 University of California, San Diego · La Jolla, California · NCT04982965

Related topics

Quick answers

How many Sciatica clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (3 trials), Pakistan (3 trials), Spain (2 trials), Canada (1 trial), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 1: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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