Steroid Injections for Back and Neck Pain: What Works Best
Official title: Success Rates and Safety in Managing Spinal and Sacro-Iliac Pain: A Critical Analysis
Run by Wilderman Medical Clinic · NCT07762170 · Data updated 2026-11-12
This study tests different steroid injections and combinations to see what provides the best pain relief and function for adults with back or neck pain.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Wilderman Medical Clinic Academic / other |
| Locations | 1 site (Thornhill, Ontario) |
| Status | Recruiting |
| Started | July 30, 2026 |
| Main results expected | December 2029 |
| Study ends | March 2030 |
| Registry record updated | August 13, 2026 |
| Trial ID | NCT07762170 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 with lumbar, cervical, or thoracic pain due to stenosis, disc herniation, radiculopathy, or FBSS who are candidates for epidural, facet, or SIJ injections and can complete standardized pain and function measures.
✕Probably not a fit
Patients unlikely to benefit include those with recent spinal surgery within 3 months, cognitive impairments, or conditions that preclude safe epidural injections.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a single-center, phase 4 interventional study that combines retrospective and prospective data to compare various ultrasound-guided steroid injection protocols across cervical, thoracic, and lumbar regions. It examines epidural, facet joint, and sacroiliac injections, comparing different steroids, dosages, and whether a local anesthetic is used. The study uses a composite measure of pain relief over time and changes in function to identify which approaches yield the most benefit. Approximately 100 patients per part are included, with analyses that aim to clarify which spinal levels and injection techniques are most effective for specific pain etiologies. The trial is led by Wilderman Medical Clinic in Thornhill, Ontario, with a focus on safety and standardized documentation of outcomes.
Why it matters
Potential benefit: If successful, this work could help clinicians choose the most effective and safe injection strategies for spinal pain, potentially improving pain control and function for patients.
How similar studies have gone: Previous work has explored various steroid injection techniques, but this study combines retrospective and prospective data to compare multiple protocols within the same patients, which is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * \>18 years of age; * Diagnosis of lumbar, cervical, or thoracic pain with various etiologies; * Eligibility to receive steroid injections for back pain, including epidural, facet joints, or SIJ injections, or other injections (e.g., local anesthetics); * Being willing and able to provide NRS pain ratings and PROMIS functionality ratings before the intervention, and the same scores plus IPR, fIPR, and PGIC at various follow-up points after the intervention; * Provide written informed consent. Exclusion Criteria: * Diagnosis of dementia, Parkinson's disease or other cognitive impairments; * Congenital or acquired polyneuropathy; * Back surgery in the month before injection treatment or planned surgery in the subsequent 3 months; * Any clinically significant acute or chronic medical condition that in the judgment of Investigator may preclude injection in the epidural space or compromise patient safety, limit patient's ability to complete the study, and/or compromise the objectives of the study; * Participation in any other competing clinical study within 3 months prior to screening and during the study period.
Where it's running
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Wilderman Medical Clinic
Thornhill, Ontario, Canada Recruiting
Study contacts
- Principal investigator: Igor Wilderman, MD — Canadian Centre for Clinical Trials
- Study coordinator: Igor Wilderman, MD
- Email: iw@drwilderman.com
- Phone: 905-886-1212
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.