Clinical trial Recruiting at 1 site Phase 4 Interventional Ages 18 and up

Steroid Injections for Back and Neck Pain: What Works Best

Official title: Success Rates and Safety in Managing Spinal and Sacro-Iliac Pain: A Critical Analysis

Run by Wilderman Medical Clinic · NCT07762170 · Data updated 2026-11-12

This study tests different steroid injections and combinations to see what provides the best pain relief and function for adults with back or neck pain.

More Neck Pain trials

Quick facts

PhasePhase 4
Study typeInterventional
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorWilderman Medical Clinic
Academic / other
Locations1 site (Thornhill, Ontario)
StatusRecruiting
StartedJuly 30, 2026
Main results expectedDecember 2029
Study endsMarch 2030
Registry record updatedAugust 13, 2026
Trial IDNCT07762170 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults over 18 with lumbar, cervical, or thoracic pain due to stenosis, disc herniation, radiculopathy, or FBSS who are candidates for epidural, facet, or SIJ injections and can complete standardized pain and function measures.

Probably not a fit

Patients unlikely to benefit include those with recent spinal surgery within 3 months, cognitive impairments, or conditions that preclude safe epidural injections.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center, phase 4 interventional study that combines retrospective and prospective data to compare various ultrasound-guided steroid injection protocols across cervical, thoracic, and lumbar regions. It examines epidural, facet joint, and sacroiliac injections, comparing different steroids, dosages, and whether a local anesthetic is used. The study uses a composite measure of pain relief over time and changes in function to identify which approaches yield the most benefit. Approximately 100 patients per part are included, with analyses that aim to clarify which spinal levels and injection techniques are most effective for specific pain etiologies. The trial is led by Wilderman Medical Clinic in Thornhill, Ontario, with a focus on safety and standardized documentation of outcomes.

Why it matters

Potential benefit: If successful, this work could help clinicians choose the most effective and safe injection strategies for spinal pain, potentially improving pain control and function for patients.

How similar studies have gone: Previous work has explored various steroid injection techniques, but this study combines retrospective and prospective data to compare multiple protocols within the same patients, which is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* \>18 years of age;
* Diagnosis of lumbar, cervical, or thoracic pain with various etiologies;
* Eligibility to receive steroid injections for back pain, including epidural, facet joints, or SIJ injections, or other injections (e.g., local anesthetics);
* Being willing and able to provide NRS pain ratings and PROMIS functionality ratings before the intervention, and the same scores plus IPR, fIPR, and PGIC at various follow-up points after the intervention;
* Provide written informed consent.

Exclusion Criteria:

* Diagnosis of dementia, Parkinson's disease or other cognitive impairments;
* Congenital or acquired polyneuropathy;
* Back surgery in the month before injection treatment or planned surgery in the subsequent 3 months;
* Any clinically significant acute or chronic medical condition that in the judgment of Investigator may preclude injection in the epidural space or compromise patient safety, limit patient's ability to complete the study, and/or compromise the objectives of the study;
* Participation in any other competing clinical study within 3 months prior to screening and during the study period.

Where it's running

  • Wilderman Medical Clinic
    Thornhill, Ontario, Canada
    Recruiting

Study contacts

  • Principal investigator: Igor Wilderman, MD — Canadian Centre for Clinical Trials
  • Study coordinator: Igor Wilderman, MD
  • Email: iw@drwilderman.com
  • Phone: 905-886-1212

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.