Condition

Geographic Atrophy clinical trials and research

• 17Clinical trials
• 2NIH research projects
• 24Countries

Newest Geographic Atrophy clinical trials

All recruiting trials (17)

• See if STL303 helps adults with geographic atrophy from AMD

  This study tests STL303 versus placebo in people 60 and older who have geographic atrophy due to age-related macular degeneration to see if it is safe and can help their vision.

  Recruiting at 3 sites Phase 2 Sitala Bio LTD · Bakersfield, California and 55 other locations · NCT07606365

• C.001 for retinal degeneration: a first-in-human dose-escalation safety test

  A first-in-human study will test the safety and tolerability of a single subretinal injection of C.001 in adults with retinal diseases involving retinal pigment epithelium degeneration.

  Recruiting at 2 sites Phase 1 Cellio Therapeutics Inc · Beverly Hills, California and 2 other locations · NCT07594236

• Central microperimetry and radial OCT in geographic atrophy

  We will test whether central microperimetry and radial OCT scans can more accurately measure how geographic atrophy progresses toward the fovea in people with or at risk for GA from age-related macular degeneration.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07556406

• One-time intravitreal SAR446597 injection for geographic atrophy due to AMD

  This trial will try a single eye injection of SAR446597 to slow geographic atrophy in people 60 and older with AMD.

  Recruiting at 35 sites Phase 1/2 Sanofi · Peoria, Arizona and 34 other locations · NCT07215234

• Dapagliflozin (an SGLT2 inhibitor) for slowing geographic atrophy in dry AMD

  This trial will test whether taking dapagliflozin once daily can slow the growth of geographic atrophy in people aged 50 and older with dry age-related macular degeneration.

  Recruiting Phase 2 Washington University School of Medicine · St Louis, Missouri · NCT07174687

• Eye injections of ABBV-6628 for geographic atrophy from age-related macular degeneration

  This trial will test whether intravitreal ABBV-6628 is safe and how the drug moves through the body in adults aged 50 and older with geographic atrophy from AMD.

  Recruiting at 5 sites Phase 1/2 AbbVie · Carmel, Indiana and 4 other locations · NCT07160179

• Daily BRX011 pill for geographic atrophy due to AMD

  A daily oral medicine called BRX011 is being tested to see if it is safe and helps slow geographic atrophy in people with age-related macular degeneration.

  Recruiting at 5 sites Phase 1/2 Biojiva LLC · Gilbert, Arizona and 16 other locations · NCT07029945

• Assessing a vision test for patients with macular degeneration and Stargardt disease

  This study is testing a new vision test to see how well it works for people with macular degeneration and Stargardt disease compared to standard vision tests.

  Recruiting Nanoscope Therapeutics Inc. · Dallas, Texas · NCT06805474

• Long-term safety assessment of JNJ-81201887 for eye condition related to aging

  This study is testing the long-term safety of a new eye treatment for age-related vision loss in people who have already tried it before.

  Recruiting at 85 sites Phase 2/3 Janssen Research & Development, LLC · Tucson, Arizona and 103 other locations · NCT06635148

• Subretinal CPCB-RPE1 implant for advanced dry AMD with geographic atrophy

  This trial will try a surgical CPCB-RPE1 implant in one eye to see if it is safe and helps people aged 55–90 with advanced dry AMD and geographic atrophy that involves the fovea.

  Recruiting at 5 sites Phase 2 Regenerative Patch Technologies, LLC · Huntington Beach, California and 4 other locations · NCT06557460

• Evaluating a stem cell treatment for geographic atrophy from dry age-related macular degeneration.

  This study is testing a new stem cell treatment for people with geographic atrophy from dry age-related macular degeneration to see if it can help improve their vision.

  Recruiting at 3 sites Phase 1/2 Eyestem Research Pvt. Ltd. · Jālna, Maharashtra and 2 other locations · NCT06394232

• Monitoring progression of non-foveal age-related macular degeneration using artificial intelligence

  This study is testing how well artificial intelligence can help track the progression of a specific type of age-related macular degeneration in patients over two years.

  Recruiting at 6 sites Medical University of Vienna · Vienna and 6 other locations · NCT06351657

• Optimizing surgical delivery of OpRegen for geographic atrophy in AMD patients

  This study is testing a new surgical method to deliver OpRegen to see if it can help people with geographic atrophy from age-related macular degeneration improve their vision safely.

  Recruiting at 17 sites Phase 2 Genentech, Inc. · Beverly Hills, California and 16 other locations · NCT05626114

• New telescope implant for patients with late-stage age-related macular degeneration

  This study is testing a new small telescope implant to see if it can help older patients with severe vision loss from age-related macular degeneration see better after surgery.

  Recruiting at 10 sites VisionCare, Inc. · Loma Linda, California and 9 other locations · NCT05438732

• Understanding Age-Related Macular Degeneration and Its Progression

  This study looks at how age-related macular degeneration develops and progresses by comparing people with the condition to healthy individuals, using non-invasive tests and personal feedback.

  Recruiting Center for Eye Research Australia · East Melbourne, Victoria · NCT04739319

• Transplanting stem cells to treat vision loss from age-related macular degeneration

  This study is testing if transplanting special stem cells into the eyes of older adults with vision loss from age-related macular degeneration can help improve their eyesight.

  Recruiting Phase 1/2 National Institutes of Health Clinical Center (CC) · Baltimore, Maryland and 1 other locations · NCT04339764

• High-resolution imaging of the retina

  This study is testing a new way to take detailed pictures of the retina to help doctors better understand and treat eye diseases like Stargardt's and age-related macular degeneration in people aged 7 and older.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT01866371

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Role of immune cells in geographic atrophy and age-related macular degeneration

  A physician-scientist is training to understand how microglia interact with retinal cells to influence geographic atrophy in age-related macular degeneration.

  NIH research Duke University · Durham, United States · NIH-11437269

• Using advanced AI to predict vision loss in patients with age-related macular degeneration

  This study is working on using smart computer models to help predict when geographic atrophy, a serious eye condition related to aging, might start or get worse, so that patients at higher risk can get the care they need more often while keeping their personal information safe.

  NIH research University of North Carolina Charlotte · Charlotte, United States · NIH-10889689

Related topics

Quick answers

How many Geographic Atrophy clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 24 countries. The most sites are in United States (14 trials), Australia (5 trials), United Kingdom (4 trials), Switzerland (3 trials), Czechia (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 5, Phase 2: 4, Phase 1: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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